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  1. Origin of thyrotropin-releasing hormone neurons that innervate the tuberomammillary nuclei

    Hypophysiotropic thyrotropin-releasing hormone (TRH) neurons function as metabolic sensors that regulate the thyroid axis and energy homeostasis....

    Edith Sánchez-Jaramillo, Gábor Wittmann, ... Ronald M. Lechan in Brain Structure and Function
    Article Open access 07 August 2022
  2. Cardiovascular and body weight regulation changes in transgenic mice overexpressing thyrotropin-releasing hormone (TRH)

    Thyrotropin-releasing hormone (TRH) plays several roles as a hormone/neuropeptide. Diencephalic TRH (dTRH) participates in the regulation of blood...

    María Silvina Landa, Silvia Inés García, ... Carlos José Pirola in Journal of Physiology and Biochemistry
    Article 11 September 2020
  3. Multifactorial Regulation of the Activity of Hypophysiotropic Thyrotropin-Releasing Hormone Neurons

    Hypophysiotropic neurons of the paraventricular nucleus of the hypothalamus that express thyrotropin-releasing hormone (TRH) control the synthesis...
    Patricia Joseph-Bravo, Lorraine Jaimes-Hoy, ... Jean-Louis Charli in Neuroanatomy of Neuroendocrine Systems
    Chapter 2021
  4. Thyrotropin-releasing hormone axonal varicosities appear to innervate dopaminergic neurons in the human hypothalamus

    Thyrotropin-releasing hormone (TRH) has a critical role in the central regulation of thyroid-stimulating hormone (TSH) from the anterior pituitary,...

    Bertalan Dudas, Istvan Merchenthaler in Brain Structure and Function
    Article 31 July 2020
  5. Tanycyte Regulation of Hypophysiotropic TRH Neurons

    Tanycytes lining the third ventricle are emerging as an integral component of the hypothalamic regulatory system. Their functions, including the...
    Ronald M. Lechan, Csaba Fekete in Glial-Neuronal Signaling in Neuroendocrine Systems
    Chapter 2021
  6. Rifaximin modulates TRH and TRH-like peptide expression throughout the brain and peripheral tissues of male rats

    Background

    The TRH/TRH-R1 receptor signaling pathway within the neurons of the dorsal vagal complex is an important mediator of the brain-gut axis....

    Albert Eugene Pekary, Albert Sattin in BMC Neuroscience
    Article Open access 21 February 2022
  7. Individual Features of the Hypothalamic—Pituitary—Thyroid Axis Functioning during Aging in Non-Human Primates

    Individual features of age-related changes in the function of the neuroendocrine systems are an important problem as the basic component of a...

    N. D. Goncharova, A. M. Ermolaeva, ... N. V. Timoshenko in Bulletin of Experimental Biology and Medicine
    Article 01 August 2023
  8. Pembrolizumab-induced secondary adrenal insufficiency due to adrenocorticotrophic hormone deficiency in a patient with non-small-cell lung carcinoma: a case report

    Background

    Pembrolizumab can cause immune-related adverse events such as adrenal insufficiency (AI). However, there is no consensus regarding...

    Tatsuhiro Fujimiya, Kanako Azuma, ... Hironori Takeuchi in Journal of Pharmaceutical Health Care and Sciences
    Article Open access 16 February 2024
  9. The Study of Biological Activity of a New Thieno[2,3-D]-Pyrimidine-Based Neutral Antagonist of Thyrotropin Receptor

    The development of low-molecular-weight antagonists of thyroid-stimulating hormone (TSH) receptor is a promising trend in the treatment of autoimmune...

    K. V. Derkach, E. A. Fokina, ... A. O. Shpakov in Bulletin of Experimental Biology and Medicine
    Article 01 April 2022
  10. Molecular evidence reveals thyrotropin intervention enhances the risk of develo** radioiodine-refractory differentiated thyroid carcinoma

    Radioiodine (RAI) is the mainstay of treatment for differentiated thyroid carcinoma (DTC) following total thyroidectomy. Nevertheless, about 5% of...

    Hilda Samimi, Vahid Haghpanah in Cancer Cell International
    Article Open access 03 February 2022
  11. Lactation and the Control of the Prolactin Secretion

    Prolactin is a polypeptide hormone secreted from the lactotrophs in the anterior pituitary gland. It is recognized as a pleiotropic hormone with...
    Raphael E. Szawka, Stephen J. Bunn, ... David R. Grattan in Neuroendocrine Regulation of Mammalian Pregnancy and Lactation
    Chapter 2024
  12. Hypothalamic-Pituitary-End-Organ Axes: Hormone Function in Female Patients with Major Depressive Disorder

    Classic hypothalamic-pituitary-end-organ feedback loops – the hypothalamic-pituitary-adrenal axis (HPAA), hypothalamic-pituitary-thyroidal axis...

    Yuncheng Zhu, **aohui Wu, ... Yiru Fang in Neuroscience Bulletin
    Article 28 April 2021
  13. Dynamics of Prolactin and Hormones of the Hypothalamic-Pituitary Thyroid Axis in Patients with Schizophrenia

    Abstract —In 70 examined patients, 34 with the first psychotic episode (FPE) and 36 with chronic schizophrenia (CS), we studied dynamics of the...

    L. N. Gorobets, A. V. Litvinov, V. S. Bulanov in Neurochemical Journal
    Article 01 March 2024
  14. Melanin-Concentrating Hormone, Neuropeptide E-I, and MCH Receptor 1

    Melanin-concentrating hormone (MCH) and neuropeptide E-I (NEI) are neuropeptides produced from the pro-melanin-concentrating hormone gene, which are...
    Giovanne B. Diniz, Jully Loyd C. Martins, ... Jackson C. Bittencourt in Neuroanatomy of Neuroendocrine Systems
    Chapter 2021
  15. Endocrine Disorders

    This chapter discusses the links between hormonal disorders and cerebellar symptoms. Cerebellar development depends on thyroid hormone (TH) which...
    Mario Manto, Christiane S. Hampe in Essentials of Cerebellum and Cerebellar Disorders
    Chapter 2023
  16. Cardiovascular Neuroendocrinology of Pregnancy

    Neuroendocrine hormones are released primarily from the anterior and posterior pituitary, under the influence of hypothalamic input, to maintain...
    Megan A. Opichka, M. Christine Livergood, ... Jennifer J. McIntosh in Cardiovascular Neuroendocrinology
    Chapter 2023
  17. Mechanisms of Homeostatically Regulated Behaviors

    Homeostasis is broadly defined as the maintenance of internal physiological conditions in the face of altered environmental conditions. Conditions...
    Joel K. Elmquist, Jeffrey M. Zigman, Clifford B. Saper in Neuroscience in the 21st Century
    Reference work entry 2022
  18. Endocrine Disorders

    Cerebellum is vulnerable to hormonal disturbances. The main endocrine disorders associated with cerebellar ataxia are thyroid diseases. Both...
    Reference work entry 2022
  19. A method for predicting drugs that can boost the efficacy of immune checkpoint blockade

    Combination therapy is a promising therapeutic strategy to enhance the efficacy of immune checkpoint blockade (ICB); however, predicting drugs for...

    Yun **a, **n Li, ... An-Yuan Guo in Nature Immunology
    Article 18 March 2024
  20. Lectures 9 and 10: Endocrine System & Hormones

    The Endocrine System consists the following organs: Hypothalamus, pituitary (anterior & posterior parts), pineal, thyroid, 4 parathyroids, thymus,...
    Chapter 2024
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