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Elimination of Chromosomes as a Mechanism for the Formation of Diploid Plants in Diploid–Tetraploid Crosses in Maize (Zea mays L.)
AbstractOne of the main components of apomictic plant reproduction is the formation of unreduced embryo sacs (ESs). Heteroploid crosses, in which...
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Chromosome-scale and haplotype-resolved genome assembly of a tetraploid potato cultivar
Potato is the most widely produced tuber crop worldwide. However, reconstructing the four haplotypes of its autotetraploid genome remained an...
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Genetic Variability of Btr1 Genes in Tetraploid Wheat Species and Aegilops speltoides Tausch
AbstractThe Btr1 ( Brittle rachis 1 ) genes are involved in the control of important domestication-related trait—brittle rachis in wheat. In the...
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Parallel subgenome structure and divergent expression evolution of allo-tetraploid common carp and goldfish
How two subgenomes in allo-tetraploids adapt to coexistence and coordinate through structure and expression evolution requires extensive studies. In...
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On the Use of the Genetic Resources of Tetraploid Wheat Triticum aethiopicum for the Development of Purple-Grain Soft Wheat with a High Content of Anthocyanins
The work considers the results on the development of purple-grain soft wheat and the study of its genetic diversity. Triticum aethiopicum Jakubz. 2 n ...
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Protoplast-Based Method for Genome Editing in Tetraploid Potato
The cultivated potato is tetraploid with four probably equivalent loci for each gene. A potato variety is furthermore commonly genetically... -
Genome assemblies of 11 bamboo species highlight diversification induced by dynamic subgenome dominance
Polyploidy (genome duplication) is a pivotal force in evolution. However, the interactions between parental genomes in a polyploid nucleus,...
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Colchicine causes prenatal cell toxicity and increases tetraploid risk
BackgroundColchicine is a clinical medicine used for relief from gout and familial Mediterranean fever. Because of its toxic effects, intravenous...
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Post-therapeutic circulating tumor cell-associated white blood cell clusters predict poor survival in patients with advanced driver gene-negative non-small cell lung cancer
PurposeThis study aimed to investigate the clinical utility of diverse aneuploid circulating tumor cell (CTC) subtypes and particularly...
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Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling
BackgroundWhole genome doubling is a frequent event during cancer evolution and shapes the cancer genome due to the occurrence of chromosomal...
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Cytogeography of the Polyploid Complex Bassia prostrata s. l. (Chenopodiaceae) Based on Genome Size Analysis and PCR-RFLP cpDNA
AbstractThe cytogeography of the polyploid complex Bassia prostrata s. l. was studied by flow cytometry (FCM) on material from 39 populations in...
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Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns
Whole chromosome and arm-level copy number alterations occur at high frequencies in tumors, but their selective advantages, if any, are poorly...
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Reference genome assemblies reveal the origin and evolution of allohexaploid oat
Common oat ( Avena sativa ) is an important cereal crop serving as a valuable source of forage and human food. Although reference genomes of many...
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Polymorphism of Pinb-1 Gene Length in Aegilops biuncialis Vis.
AbstractPuroindolines (puroindoline a and puroindoline b) determine the texture of the wheat grain, which affects milling properties of the grain and...
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Karyotype Analysis and Systematic Relationship in the Iranian Astragalus L. (Fabaceae)
AbstractThe karyotype characteristics of 24 taxa of Iranian Astragalus genus from different geographic origins were studied and their relation with...
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RAD6 inhibition enhances paclitaxel sensitivity of triple negative breast cancer cells by aggravating mitotic spindle damage
BackgroundPaclitaxel (PTX), a first-line therapy for triple negative breast cancers (TNBC) induces anti-tumor activity by microtubule stabilization...
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Plant domestication shapes rhizosphere microbiome assembly and metabolic functions
BackgroundThe rhizosphere microbiome, which is shaped by host genotypes, root exudates, and plant domestication, is crucial for sustaining...
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Polyploidy Induction and Ploidy Level Determination in Annual and Perennial Diploid Medicago Species Using the Enumeration of Chloroplasts of Stomata Guard Cells
AbstractPrimary screening of original diploid species and induced autotetraploids after induction of single node cutting of three populations of...
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Ploidy Modification for Plant Breeding Using In Vitro Organogenesis: A Case in Eggplant
The use of antimitotic agents such as colchicine has been common to obtain polyploid organisms. However, this approach entails certain problems, from... -
Beyond Death: Unmasking the Intricacies of Apoptosis Escape
Apoptosis, or programmed cell death, maintains tissue homeostasis by eliminating damaged or unnecessary cells. However, cells can evade this process,...