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A study from structural insight to the antiamyloidogenic and antioxidant activities of flavonoids: scaffold for future therapeutics of Alzheimer’s disease
Neurotoxicity occurs in Alzheimer’s disease due to the formation of Amyloid-β peptide aggregates and damage caused by oxidative stress. Upon...
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RETRACTED ARTICLE:Flavonoids modulate multidrug resistance through wnt signaling in P-glycoprotein overexpressing cell lines
BackgroundWnt signaling has been linked with P-glycoprotein (P-gp) overexpression and which was mainly mediated by β-catenin nuclear translocation....
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Antithrombotic and antiplatelet effects of plant-derived compounds: a great utility potential for primary, secondary, and tertiary care in the framework of 3P medicine
Thromboembolism is the third leading vascular disease, with a high annual incidence of 1 to 2 cases per 1000 individuals within the general...
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Recent Advances in Computational Modeling of BACE1 Inhibitors as Anti-Alzheimer Agents
A growing number of people worldwide are being affected by aging-associated neurodegenerative illnesses, the most prevalent of which, Alzheimer’s, is...
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Antagonistic Herb-Drug Interactions
According to WHO drug strategy survey, majority of the population in both develo** and developed countries use herbal medicines leading to chances...
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Chemical Composition and Biological Uses of Crocus sativus L. (Saffron)
Crocus sativus L. (Iridaceae) is a stemless herb produced in Iran, Afghanistan, Turkey, Spain, Greece, and India. It is commonly known as saffron and...
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Kaempferia diterpenoids and flavonoids: an overview on phytochemistry, biosynthesis, synthesis, pharmacology, and pharmacokinetics
Kaempferia species have contained various crucial ethnobotanical features, and are being used as traditional folk medicines in some Southeast Asia....
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Blood and Urinary Flavonoids
Flavonoids are a large and complex group of phenolic compounds present in plant origin foods that may promote health and prevent diseases in humans....
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Blood and Urinary Flavonoids
Flavonoids are a large and complex group of phenolic compounds present in plant origin foods that may promote health and prevent diseases in humans....
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Isolation and evaluation of antiviral plant compounds against respiratory disease-causing viruses: a review
Influenza viruses are major concern worldwide due to their fast ability to spread, and causing the respiratory illness of varying severity. The rate...
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Inducibility of Foreign Compound Metabolic Enzymes
Induction of metabolic enzymes plays a significant role in the susceptibility of individuals to foreign compound - mediated toxicities. The family of...
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Phytochemicals and Their Role in Pharmaceuticals
Researchers and pharmacists are replacing synthetic chemicals with natural resources for drug manufacturing purposes. Plants produce secondary...
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Flavonoids: Health Benefits and Their Potential Use in Food Systems
In the mid-1980s, the term “functional foods” was introduced in Japan with the definition of processed foods comprising ingredients that assist or...
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Biomarkers of moderate alcohol intake and alcoholic beverages: a systematic literature review
The predominant source of alcohol in the diet is alcoholic beverages, including beer, wine, spirits and liquors, sweet wine, and ciders....
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A Systematic Review of Drug Metabolism Studies of Plants With Anticancer Properties: Approaches Applied and Limitations
Background and ObjectivesHepatic drug metabolism is a key influence on the efficacy and safety of medicines from both chemical and natural product...
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Pharmacokinetics and Pharmacodynamics of Polyphenols
Polyphenols possess numerous biological effects but have low oral bioavailability since they are extensively metabolized by phase 1 (CYP P450 family)...
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Aryl hydrocarbon receptor activation mediates kidney disease and renal cell carcinoma
The aryl hydrocarbon receptor (AhR) is a well-known ligand-activated cytoplasmic transcription factor that contributes to cellular responses against...
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Pharmacokinetics and Bioavailability Enhancement of Natural Products
Many natural products show promising activities in in vitro studies and preclinical in vivo studies, including cancer chemoprevention agents....
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The Artemisia Genus: Panacea to Several Maladies
The genus Artemisia belongs to the family Asteraceae which has now become the subject of great attraction because of its rich species diversity and...
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Biomarkers of food intake for Allium vegetables
Allium vegetables are widely consumed around the world and are known for their potential bioactive components improving human health. These effects...
