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Nanocarrier – Mediated Salinomycin Delivery Induces Apoptosis and Alters EMT Phenomenon in Prostate Adenocarcinoma
Salinomycin (Sal) has been recently discovered as a novel chemotherapeutic agent against various cancers including prostate cancer which is one of...
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Risk of colorectal adenocarcinoma in men receiving androgen deprivation therapy for prostate cancer; a nationwide cohort study
PurposeTo assess whether androgens play a role in explaining the sex related differences in the incidence of colorectal cancer (CRC).
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High GLUT1 membrane expression and low PSMA membrane expression in Ductal Adenocarcinoma and Intraductal Carcinoma of the prostate
BackgroundBoth Ductal Adenocarcinoma (DAC) and Intraductal Carcinoma (IDC) of the prostate are generally associated with aggressive clinical behavior...
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ORC6, a novel prognostic biomarker, correlates with T regulatory cell infiltration in prostate adenocarcinoma: a pan-cancer analysis
BackgroundThe origin recognition complex (ORC), a six-subunit DNA-binding complex, participates in DNA replication in cancer cells. Specifically in...
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Identification of Bone Metastatic and Prognostic Alternative Splicing Signatures in Prostate Adenocarcinoma
As the most common nonepithelial malignancy, prostate adenocarcinoma (PRAD) is the fifth chief cause of cancer mortality in men. Distant metastasis...
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Prostate Cancer
Prostate cancer is a highly prevalent cancer in older men. Its clinical course is extremely variable. Detection of prostate cancer has been improved...
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FASN multi-omic characterization reveals metabolic heterogeneity in pancreatic and prostate adenocarcinoma
BackgroundPancreatic ductal adenocarcinoma (PDAC) and prostate cancer (PCa) are among the most prevalent malignant tumors worldwide. There is now a...
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Health-related quality of life of metastatic prostate cancer patients treated with prostate Radiotherapy
BackgroundThe impact of prostate radiotherapy on patient-reported health-related quality of life (HRQoL) significantly influences the outcomes of...
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Prostate Cancer: Epidemiology, Etiology, Pathogenesis, and Risk Factors
Prostate cancer is today the most common cancer in men in developed countries. The very high incidence of prostate cancer in the developed world...
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Rare histological prostate cancer subtypes: Cancer-specific and other-cause mortality
BackgroundTo assess cancer-specific mortality (CSM) and other-cause mortality (OCM) rates in patients with rare histological prostate cancer subtypes.
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Basic Insights into Tumor Microenvironment in Prostate Cancer
Prostate cancer, a prominent malignancy impacting men worldwide, is characterized by a dynamic and intricate interplay between cancer cells and their...
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The novel transcriptomic signature of angiogenesis predicts clinical outcome, tumor microenvironment and treatment response for prostate adenocarcinoma
Angiogenesis plays the critical roles in promoting tumor progression, aggressiveness, and metastasis. Although few studies have revealed some...
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Tumor-antigens and immune landscapes identification for prostate adenocarcinoma mRNA vaccine
Prostate adenocarcinoma (PRAD) is a leading cause of death among men. Messenger ribonucleic acid (mRNA) vaccine presents an attractive approach to...
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Histopathological and Molecular Markers in the Assessment of Prostate Cancer Aggressivity
Prostate cancer (PCa) in most patients does not cause significant clinical symptoms, but high-risk disease, accounting for approximately 15% of PCa,...
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Stereotactic Radiotherapy in the Treatment of Prostate Cancer
Stereotactic body radiotherapy (SBRT) is a technologically sophisticated form of radiotherapy and well-established treatment option for patients with...
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Characterisation of cell lines derived from prostate cancer patients with localised disease
BackgroundProstate cancer is a broad-spectrum disease, spanning from indolent to a highly aggressive lethal malignancy. Prostate cancer cell lines...
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Rab3B enhances the stabilization of DDX6 to promote lung adenocarcinoma aggressiveness
BackgroundLiver kinase B1 ( LKB1 ) is frequently mutated in lung adenocarcinoma, and its loss contributes to tumor progression.
Methods ...
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Immunogenomic profiles associated with response to life-prolonging agents in prostate cancer
Prostate cancer is the most commonly diagnosed cancer but the management of advanced prostate cancer remains a therapeutic challenge, despite the...
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Inference of core needle biopsy whole slide images requiring definitive therapy for prostate cancer
BackgroundProstate cancer is often a slowly progressive indolent disease. Unnecessary treatments from overdiagnosis are a significant concern,...
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Current Pathophysiology, Treatment, and Future Perspective for Prostate Cancer
Prostate Cancer (PCa) is one of the most common types of cancer in Western countries Asia due to uncontrolled cell proliferation of the prostate...