Search
Search Results
-
Claudin18.2 as a potential therapeutic target for primary ovarian mucinous carcinomas and metastatic ovarian mucinous carcinomas from upper gastrointestinal primary tumours
BackgroundThe vast majority of ovarian mucinous carcinomas are metastatic tumours derived from nonovarian primary cancers, typically gastrointestinal...
-
Gene S-phase kinase associated protein 2 is a novel prognostic marker in human neoplasms
BackgroundNeoplasms are a series of diseases affecting human health. Prognostic and tumor status–related markers for various tumors should be...
-
Peripheral PD-1 and Tim-3 percentages are associated with primary sites and pathological types of peritoneal neoplasms
PurposeProgrammed death-1 (PD-1) and T cell immunoglobulin and mucin-domain-containing molecule 3(Tim-3) may be used as the biomarkers for the...
-
Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T
In recent decades, immune checkpoint blockade and chimeric antigen receptor T cell (CAR-T) therapy are two milestone achievements in clinical...
-
Hematologic toxicities of chemotherapy in breast and ovarian cancer patients carrying BRCA1/BRCA2 germline pathogenic variants. A single center experience and review of the literature
BRCA1 and BRCA2 play a central role in DNA repair and their germline pathogenic variants (g BRCA ) confer a high risk for develo** breast and ovarian...
-
CSGALNACT2 restricts ovarian cancer migration and invasion by modulating MAPK/ERK pathway through DUSP1
PurposeOvarian cancer is one of the leading causes of cancer-related death among women. CSGALNACT2 is a vital Golgi transferase and is related to a...
-
Specific expression profile of follicular fluid-derived exosomal microRNAs in patients with diminished ovarian reserve
BackgroundDiminished ovarian reserve (DOR) is defined as a reduction in ovarian reserve and oocyte quality. The pathophysiology of DOR has not been...
-
Increased FOXJ1 protein expression is associated with improved overall survival in high-grade serous ovarian carcinoma: an Ovarian Tumor Tissue Analysis Consortium Study
BackgroundRecently, we showed a >60% difference in 5-year survival for patients with tubo-ovarian high-grade serous carcinoma (HGSC) when stratified...
-
Immunotherapy in Ovarian Cancer
Despite advances in surgery and chemotherapy, ovarian cancer remains one of the most lethal malignancies. Hence, the implementation of novel...
-
Survival rate of ovarian cancer in Asian countries: a systematic review and meta-analysis
BackgroundOvarian cancer is amongst one of the most commonly occurring cancers affecting women, and the leading cause of gynecologic related cancer...
-
The genetic profile and molecular subtypes of human pseudomyxoma peritonei and appendiceal mucinous neoplasms: a systematic review
Pseudomyxoma peritonei (PMP) is a rare, progressive, slowly growing neoplastic condition which is poorly understood, with a 5-year progression-free...
-
Molecular Characterization of Single Circulating Tumor Cells in Breast and Ovarian Cancer
Epithelial ovarian cancer (EOC)Epithelial ovarian cancer (EOC) still has the highest mortality rate of all gynecological malignancies, diagnosed...
-
DNA Methylation of a Group of Long Non-Coding RNA Genes at Different Stages of Ovarian Cancer Dissemination
There are three types of metastases in ovarian cancer: lymphogenous, hematogenous, and peritoneal. Dissemination of the tumor in the peritoneum is...
-
Nanocargos designed with synthetic and natural polymers for ovarian cancer management
Ovarian cancer cells usually spread in the peritoneal region, and if chemotherapeutic drugs can be given in these regions with proximity, then the...
-
Tumor-associated fibrosis: a unique mechanism promoting ovarian cancer metastasis and peritoneal dissemination
Epithelial ovarian cancer (EOC) is often diagnosed in advanced stage with peritoneal dissemination. Recent studies indicate that aberrant...
-
Ovarian Cancer Biomarkers: Immunohistochemical Surrogates for Molecular Alterations
Outstanding advances over the last two decades have revolutionized ovarian cancer knowledge and therapy, moving toward a more personalized molecular...
-
SPP1 is a prognostic related biomarker and correlated with tumor-infiltrating immune cells in ovarian cancer
BackgroundSecreted phosphoprotein 1 (SPP1) plays a vital role in tumor progression of multiple cancer types However, it still awaits further...
-
Nanotechnology-Based Nucleic Acid Vaccines for Treatment of Ovarian Cancer
Anticancer vaccines represent a promising approach for effective treatment of cancer and along with recent advantages of nucleic acid-based vaccines...
-
UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
BackgroundEpithelial ovarian cancer (EOC) is a global health burden, with the poorest five-year survival rate of the gynecological malignancies due...
-
Harnessing preclinical models for the interrogation of ovarian cancer
Ovarian cancer (OC) is a heterogeneous malignancy with various etiology, histopathology, and biological feature. Despite accumulating understanding...
