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Effect of different non-pharmacologic placebo treatments on migraine prevention: a network meta-analysis of randomized controlled trials
BackgroundPlacebo control plays an important role in evaluating the effectiveness of interventions. Specifying differential effects of various...
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Stress reduction strategies in breast cancer: review of pharmacologic and non-pharmacologic based strategies
Breast cancer is the most common cancer diagnosed in women. It is associated with multiple symptoms in both patients and caregivers, such as stress,...
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Management of Common Scabies
The management of common scabies infestation has pharmacologic and non-pharmacologic elements. Pharmacologic intervention consists of anti-parasitic...
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Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia
Cerebellar ataxias are a heterogenous group of degenerative disorders for which we currently lack effective and disease-modifying interventions. The...
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Pharmacological interventions for preventing atrial fibrillation after lung surgery: systematic review and meta-analysis
BackgroundPostoperative atrial fibrillation/flutter (POAF) is one of the most common cardiac complications after lung surgery. We aimed to assess the...
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High Altitude Sickness and Antioxidant Interventions
High altitude sickness (HAS) has been one of the important environmental challenges occurring as a result of the failure of the physiological...
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Efficacy and safety of different pharmacological interventions in the treatment of tardive dyskinesia: a systematic review and network meta-analysis
ObjectivesThe aim of this study is to indirectly compare and rank the different drugs that have been studied in randomized clinical trials (RCTs) in...
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Develo** dietary interventions as therapy for cancer
Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic alterations and degree of interaction with systemic...
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Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations
Heterozygous loss-of-function mutations in progranulin ( GRN ) cause frontotemporal dementia (FTD), a leading cause of early-onset dementia...
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Serotonin Transporter (SLC6A4) and FK506-Binding Protein 5 (FKBP5) Genotype and Methylation Relationships with Response to Meditation in Veterans with PTSD
Meditation-based interventions are novel and effective non-pharmacologic treatments for veterans with PTSD. We examined relationships between...
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Circadian rhythms: influence on physiology, pharmacology, and therapeutic interventions
Circadian rhythms are ubiquitous phenomena that recur daily in a self-sustaining, entrainable, and oscillatory manner, and orchestrate a wide range...
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Capparis spinosa improves non-alcoholic steatohepatitis through down-regulating SREBP-1c and a PPARα-independent pathway in high-fat diet-fed rats
ObjectiveNon-alcoholic steatohepatitis (NASH) has become a global medical problem. Currently, there is no approved pharmacologic treatment for this...
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Acupuncture Treatment for Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disease that costs a growing burden on patients, family members, healthcare systems, and society...
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Pharmacological and cell-based treatments to increase local skin flap viability in animal models
Local skin flaps are frequently employed for wound closure to address surgical, traumatic, congenital, or oncologic defects. (1) Despite their...
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To restrict or not to restrict? Practical considerations for optimizing dietary protein interactions on levodopa absorption in Parkinson’s disease
Administration of levodopa for Parkinson’s disease (PD) has remained the most effective therapy for symptom management despite being in use for over...
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Phosphodiesterase-5 (PDE-5) Inhibitors as Therapy for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury
Multiple phase III randomized controlled trials (RCTs) for pharmacologic interventions in traumatic brain injury (TBI) have failed despite promising...
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Therapeutic non-invasive brain treatments in Alzheimer’s disease: recent advances and challenges
Alzheimer’s disease (AD) is one of the major neurodegenerative diseases and the most common form of dementia. Characterized by the loss of learning,...
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Treatments that are perceived to be helpful for non-neuropathic pain after traumatic spinal cord injury: a multicenter cross-sectional survey
Study designCross-sectional survey.
ObjectivesThe objective of the study was to identify the treatments that people with traumatic spinal cord...
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Postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders after COVID-19 infection: a case series of 20 patients
ObjectiveTo describe clinical features, diagnostic findings, treatments, and outcomes in patients with new-onset postural orthostatic tachycardia...
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Cellular senescence and senolytics: the path to the clinic
Interlinked and fundamental aging processes appear to be a root-cause contributor to many disorders and diseases. One such process is cellular...
