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Showing 1-20 of 1,417 results
  1. Novel Mutation in the Moesin (MSN) Gene Leads to Immunodeficiency with Epstein–Barr Virus (EBV) Infection and Dermatomyositis-Like Symptoms

    Purpose

    Moesin (MSN) deficiency is a recently reported combined immunodeficiency, and few cases have been reported to date. We describe a Chinese...

    Bijun Sun, Luyao Liu, ... **qiao Sun in Journal of Clinical Immunology
    Article 26 June 2024
  2. The cell adhesion molecule TMIGD1 binds to moesin and regulates tubulin acetylation and cell migration

    Background

    The cell adhesion molecule transmembrane and immunoglobulin (Ig) domain containing1 (TMIGD1) is a novel tumor suppressor that plays...

    Nader Rahimi, Rachel X. Y. Ho, ... Catherine E. Costello in Journal of Biomedical Science
    Article Open access 09 September 2021
  3. CD44 cross-linking increases malignancy of breast cancer via upregulation of p-Moesin

    Background

    CD44 is highly expressed in most cancer cells and its cross-linking pattern is closely related to tumor migration and invasion. However,...

    Song Hu, **aoxing Shi, ... Feng Gao in Cancer Cell International
    Article Open access 23 November 2020
  4. Moesin is involved in microglial activation accompanying morphological changes and reorganization of the actin cytoskeleton

    Moesin is a member of the ezrin, radixin and moesin (ERM) proteins that are involved in the formation and/or maintenance of cortical actin...

    Tomonori Okazaki, Daichi Saito, ... Shinji Asano in The Journal of Physiological Sciences
    Article Open access 31 October 2020
  5. Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat brain partly via affecting membrane expression of ezrin/radixin/moesin proteins

    Breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) are co-located at blood–brain barrier (BBB) cells, preventing their substrates from...

    Tong Wu, Yun Sheng, ... Li Liu in Acta Pharmacologica Sinica
    Article 08 February 2021
  6. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer’s disease

    Background

    Proteomic characterization of microglia provides the most proximate assessment of functionally relevant molecular mechanisms of...

    Sruti Rayaprolu, Tianwen Gao, ... Srikant Rangaraju in Molecular Neurodegeneration
    Article Open access 07 May 2020
  7. The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome

    Amyloid plaques contain many proteins in addition to beta amyloid (Aβ). Previous studies examining plaque-associated proteins have shown these...

    Eleanor Drummond, Tomas Kavanagh, ... Thomas Wisniewski in Acta Neuropathologica Communications
    Article Open access 13 April 2022
  8. Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases

    Background

    Podoplanin (PDPN) is a mucin-type transmembrane glycoprotein specific to the lymphatic system. PDPN expression has been found in various...

    Justyna Sikorska, Damian Gaweł, ... Barbara Czarnocka in BMC Cancer
    Article Open access 17 January 2019
  9. Rhoj Is a Novel Target for Progression and Invasion of Glioblastoma by Impairing Cytoskeleton Dynamics

    Rho GTPase family members were identified as critical regulators of cell morphology, actin cytoskeleton organization, cell movement, and cell cycle...

    Mei Wang, ** **a in Neurotherapeutics
    Article 21 August 2020
  10. Internalization of NKCC2 is impaired in thick ascending limb of Henle in moesin knockout mice

    Moesin is expressed in several types of cells including epithelial and endothelial cells. Several groups reported that moesin plays important roles...

    Kotoku Kawaguchi, Ryo Hatano, ... Shinji Asano in Pflügers Archiv - European Journal of Physiology
    Article 15 March 2018
  11. The relationship and clinical significance of lactylation modification in digestive system tumors

    Lactylation, an emerging post-translational modification, plays a pivotal role in the initiation and progression of digestive system tumors. This...

    Gang Wang, **aosu Zou, ... Shenhong Qu in Cancer Cell International
    Article Open access 15 July 2024
  12. Guillain Barre Syndrome as a Complication of Infections Including COVID-19: a Review

    Purpose of Review

    The purpose was to analyze scientific findings on Guillain Barre Syndrome (GBS) related to COVID-19 and emphasize its relationship...

    Shruti V. Kurup, Pratiksha M. Patil, ... Mohan K. Kale in Current Pharmacology Reports
    Article 22 September 2023
  13. ERRα coordinates actin and focal adhesion dynamics

    Cell migration depends on the dynamic organisation of the actin cytoskeleton and assembly and disassembly of focal adhesions (FAs). However, the...

    Violaine Tribollet, Catherine Cerutti, ... Christelle Forcet in Cancer Gene Therapy
    Article 04 April 2022
  14. Aging Biomarker SMP30 into a New Phase of Vitamin C and Aging Research

    Proteomics has provided comprehensive information in terms of agingAging in general and, in particular, regarding age-associated molecules, including...
    Akihito Ishigami in Aging Mechanisms II
    Chapter 2022
  15. Highlighting the role of CD44 in cervical cancer progression: immunotherapy’s potential in inhibiting metastasis and chemoresistance

    Cervical cancer affects thousands of women globally with recurring high-risk HPV infections being at the centre of cervical pathology. Oncological...

    Cayleigh de Sousa, Carla Eksteen, ... Anna-Mart Engelbrecht in Immunologic Research
    Article Open access 31 May 2024
  16. Moesin expression by tumor cells is an unfavorable prognostic biomarker for oral cancer

    Background

    Moesin is a member of the ERM (ezrin, radixin and moesin) proteins that participate in cell migration and tumor invasion through...

    Francisco Bárbara Abreu Barros, Agnes Assao, ... Denise Tostes Oliveira in BMC Cancer
    Article Open access 08 January 2018
  17. The role of noble bumblebee (Bombus terrestris) queen glycosaminoglycan in aged rat and gene expression profile based on DNA microarray

    Glycosaminoglycans (GAGs) have been used to diminish the deleterious effects associated with aging by preventing the destruction of cartilage, bone,...

    Mi Young Ahn, Hyung Joo Yoon, ... Kun-Koo Park in Toxicological Research
    Article 26 October 2020
  18. Moesin

    Reference work entry 2018
  19. MSN (Moesin)

    Katharine A. Michie, Sophia C. Goodchild, Paul M. G. Curmi in Encyclopedia of Signaling Molecules
    Reference work entry 2018
  20. PTBP1 plays an important role in the development of gastric cancer

    Background

    Polypyrimidine tract binding protein 1 (PTBP1) has been found to play an important role in the occurrence and development of various...

    Zewen Chu, Miao Zhu, ... Yanqing Liu in Cancer Cell International
    Article Open access 05 September 2023
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