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Showing 1-20 of 3,826 results
  1. Altered regional homogeneity following moxibustion in mild cognitive impairment

    Moxibustion has a definite clinical effect in improving the cognitive condition in individuals with mild cognitive impairment (MCI), but its...

    Qing** Zhang, Lingyan Liang, ... Demao Deng in Brain Imaging and Behavior
    Article 12 December 2023
  2. Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease

    Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential...

    Velma T. E. Aho, Matthias Klee, ... Gelani Zelimkhanov in npj Parkinson's Disease
    Article Open access 06 April 2024
  3. Disrupted morphological brain network organization in subjective cognitive decline and mild cognitive impairment

    We aim to investigate the alterations in gray matter for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) from the perspective...

    Yuxin Chen, Lingyan Liang, ... Demao Deng in Brain Imaging and Behavior
    Article 26 December 2023
  4. CSF neurochemical profile and cognitive changes in Parkinson’s disease with mild cognitive impairment

    Pathophysiological substrate(s) and progression of Parkinson’s disease (PD) with mild cognitive impairment (PD-MCI) are still matter of debate....

    Federico Paolini Paoletti, Lorenzo Gaetani, ... Lucilla Parnetti in npj Parkinson's Disease
    Article Open access 24 April 2023
  5. Estimating attrition in mild-to-moderate Alzheimer’s disease and mild cognitive impairment clinical trials

    Background

    Participant retention is a key factor that affects clinical trial integrity. Trial protocols estimate attrition as a function of sample...

    Marina Ritchie, Daniel L. Gillen, Joshua D. Grill in Alzheimer's Research & Therapy
    Article Open access 21 November 2023
  6. Impact of distinct cognitive domains on gait variability in individuals with mild cognitive impairment and dementia

    Background

    Gait variability is a common feature in neurodegenerative diseases and has been linked to cognitive impairment. Despite this link, the...

    Edward Ofori, Ferdinand Delgado, ... Mark Gudesblatt in Experimental Brain Research
    Article 16 May 2024
  7. Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia

    Background

    Disease-modifying treatments for Alzheimer’s disease highlight the need for early detection of cognitive decline. However, at present, most...

    Ali Jannati, Claudio Toro-Serey, ... Alvaro Pascual-Leone in Alzheimer's Research & Therapy
    Article Open access 02 January 2024
  8. Deep-learning-optimized microstate network analysis for early Parkinson’s disease with mild cognitive impairment

    Graph-theory-based topological impairment of the whole-brain network has been verified to be one of the characteristics of mild cognitive impairment...

    Luxiao Zhang, **ao Shen, ... Chen Liu in Cognitive Neurodynamics
    Article 18 April 2024
  9. The Role of Cognitive Reserve in Protecting Cerebellar Volumes of Older Adults with mild Cognitive Impairment

    The present study aims to investigate the relationship between cerebellar volumes and cognitive reserve in individuals with Mild Cognitive Impairment...

    Maria Devita, Giulia Debiasi, ... Alessandra Coin in The Cerebellum
    Article Open access 19 April 2024
  10. Uncovering heterogeneous cognitive trajectories in mild cognitive impairment: a data-driven approach

    Background

    Given the complex and progressive nature of mild cognitive impairment (MCI), the ability to delineate and understand the heterogeneous...

    **wu Wang, Teng Ye, ... Jie Zhang in Alzheimer's Research & Therapy
    Article Open access 20 March 2023
  11. Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis

    Background

    Health-related quality of life (HR-QoL) is an important outcome for patients and crucial for demonstrating the value of new treatments....

    Sandar Aye, Vincent Bouteloup, ... Linus Jönsson in Alzheimer's Research & Therapy
    Article Open access 15 November 2023
  12. Growth-Associated Protein 43 and Tensor-Based Morphometry Indices in Mild Cognitive Impairment

    Growth-associated protein 43 (GAP-43) is found in the axonal terminal of neurons in the limbic system, which is affected in people with Alzheimer’s...

    Homa Seyedmirzaei, Amirhossein Salmannezhad, ... Sara Shaki Baher in Neuroinformatics
    Article 17 April 2024
  13. Optimizing detection of Alzheimer’s disease in mild cognitive impairment: a 4-year biomarker study of mild behavioral impairment in ADNI and MEMENTO

    Background

    Disease-modifying drug use necessitates better Alzheimer disease (AD) detection. Mild cognitive impairment (MCI) leverages cognitive...

    Zahinoor Ismail, Rebeca Leon, ... Eric E. Smith in Molecular Neurodegeneration
    Article Open access 29 July 2023
  14. Validation of the Slovenian version of the Montreal Cognitive Assessment Scale as a screening tool for the detection of mild cognitive impairment

    Objective

    The Montreal cognitive assessment scale (MoCA) is commonly used for detecting individuals with mild cognitive impairment (MCI). The aim of...

    Andreja Špeh, Irena Kalar, ... Milica Gregorič Kramberger in Acta Neurologica Belgica
    Article Open access 04 March 2024
  15. The criteria used to rule out mild cognitive impairment impact dementia incidence rates in subjective cognitive decline

    Background

    The research criteria for subjective cognitive decline (SCD) exclude mild cognitive impairment (MCI), but do not stipulate the use of...

    Tim Whitfield, Leonidas Chouliaras, ... Zuzana Walker in Alzheimer's Research & Therapy
    Article Open access 28 June 2024
  16. High-density lipoprotein cholesterol is associated with lowered cognitive recovery among acute ischemic stroke patients with mild cognitive impairment

    High-density lipoprotein (HDL) has been documented to be related to mild cognitive impairment (MCI) and dementia occurrence; however, the underlying...

    Rui Wang, Zhuomin Jiao, ... Jie Xu in Acta Neurologica Belgica
    Article 26 September 2023
  17. Neurophysiological markers in community-dwelling older adults with mild cognitive impairment: an EEG study

    Background

    Neurodegeneration and structural changes in the brain due to amyloid deposition have been observed even in individuals with mild cognitive...

    Osamu Katayama, Yaakov Stern, ... Hiroyuki Shimada in Alzheimer's Research & Therapy
    Article Open access 15 December 2023
  18. The age-specific comorbidity burden of mild cognitive impairment: a US claims database study

    Background

    Identifying individuals with mild cognitive impairment (MCI) who are likely to progress to Alzheimer’s disease and related dementia...

    Gang Li, Nicola Toschi, ... Harald Hampel in Alzheimer's Research & Therapy
    Article Open access 06 December 2023
  19. Assessment and Cognitive Training of Patients with Mild Cognitive Impairment Using Mobile Devices

    Dementia has become one of the leading causes of disability in the elderly worldwide. Early detection and intervention through cognitive evaluation,...
    Panagiota Giannopoulou, Spyridon Doukakis in Handbook of Computational Neurodegeneration
    Reference work entry 2023
  20. Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns

    Background

    Alzheimer’s disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of...

    Ondrej Lerch, Daniel Ferreira, ... Eric Westman in Alzheimer's Research & Therapy
    Article Open access 05 July 2024
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