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Altered regional homogeneity following moxibustion in mild cognitive impairment
Moxibustion has a definite clinical effect in improving the cognitive condition in individuals with mild cognitive impairment (MCI), but its...
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Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease
Gut microbiome differences between people with Parkinson’s disease (PD) and control subjects without Parkinsonism are widely reported, but potential...
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Disrupted morphological brain network organization in subjective cognitive decline and mild cognitive impairment
We aim to investigate the alterations in gray matter for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) from the perspective...
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CSF neurochemical profile and cognitive changes in Parkinson’s disease with mild cognitive impairment
Pathophysiological substrate(s) and progression of Parkinson’s disease (PD) with mild cognitive impairment (PD-MCI) are still matter of debate....
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Estimating attrition in mild-to-moderate Alzheimer’s disease and mild cognitive impairment clinical trials
BackgroundParticipant retention is a key factor that affects clinical trial integrity. Trial protocols estimate attrition as a function of sample...
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Impact of distinct cognitive domains on gait variability in individuals with mild cognitive impairment and dementia
BackgroundGait variability is a common feature in neurodegenerative diseases and has been linked to cognitive impairment. Despite this link, the...
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Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia
BackgroundDisease-modifying treatments for Alzheimer’s disease highlight the need for early detection of cognitive decline. However, at present, most...
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Deep-learning-optimized microstate network analysis for early Parkinson’s disease with mild cognitive impairment
Graph-theory-based topological impairment of the whole-brain network has been verified to be one of the characteristics of mild cognitive impairment...
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The Role of Cognitive Reserve in Protecting Cerebellar Volumes of Older Adults with mild Cognitive Impairment
The present study aims to investigate the relationship between cerebellar volumes and cognitive reserve in individuals with Mild Cognitive Impairment...
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Uncovering heterogeneous cognitive trajectories in mild cognitive impairment: a data-driven approach
BackgroundGiven the complex and progressive nature of mild cognitive impairment (MCI), the ability to delineate and understand the heterogeneous...
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Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis
BackgroundHealth-related quality of life (HR-QoL) is an important outcome for patients and crucial for demonstrating the value of new treatments....
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Growth-Associated Protein 43 and Tensor-Based Morphometry Indices in Mild Cognitive Impairment
Growth-associated protein 43 (GAP-43) is found in the axonal terminal of neurons in the limbic system, which is affected in people with Alzheimer’s...
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Optimizing detection of Alzheimer’s disease in mild cognitive impairment: a 4-year biomarker study of mild behavioral impairment in ADNI and MEMENTO
BackgroundDisease-modifying drug use necessitates better Alzheimer disease (AD) detection. Mild cognitive impairment (MCI) leverages cognitive...
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Validation of the Slovenian version of the Montreal Cognitive Assessment Scale as a screening tool for the detection of mild cognitive impairment
ObjectiveThe Montreal cognitive assessment scale (MoCA) is commonly used for detecting individuals with mild cognitive impairment (MCI). The aim of...
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The criteria used to rule out mild cognitive impairment impact dementia incidence rates in subjective cognitive decline
BackgroundThe research criteria for subjective cognitive decline (SCD) exclude mild cognitive impairment (MCI), but do not stipulate the use of...
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High-density lipoprotein cholesterol is associated with lowered cognitive recovery among acute ischemic stroke patients with mild cognitive impairment
High-density lipoprotein (HDL) has been documented to be related to mild cognitive impairment (MCI) and dementia occurrence; however, the underlying...
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Neurophysiological markers in community-dwelling older adults with mild cognitive impairment: an EEG study
BackgroundNeurodegeneration and structural changes in the brain due to amyloid deposition have been observed even in individuals with mild cognitive...
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The age-specific comorbidity burden of mild cognitive impairment: a US claims database study
BackgroundIdentifying individuals with mild cognitive impairment (MCI) who are likely to progress to Alzheimer’s disease and related dementia...
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Assessment and Cognitive Training of Patients with Mild Cognitive Impairment Using Mobile Devices
Dementia has become one of the leading causes of disability in the elderly worldwide. Early detection and intervention through cognitive evaluation,... -
Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns
BackgroundAlzheimer’s disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of...