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Elucidation of how the Mir-23-27-24 cluster regulates development and aging
MicroRNAs (miRNAs) are pivotal regulators of gene expression and are involved in biological processes spanning from early developmental stages to the...
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Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis
BackgroundTo test the hypothesis that activated extracellular signal-regulated kinase (ERK) regulates P65-miR23a/27a/24 axis in gastric cancer (GC)...
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Regulation of Noncoding RNA by Nutraceuticals: Implication in Neurological Disorders and Cancer
Noncoding RNAs (ncRNAs) are RNAs transcribed from genes but are not translated. The ncRNAs such as lncRNAs and miRNAs play an important role in the... -
High-throughput sequencing identifies HIV-1-replication- and latency-related miRNAs in CD4+ T cell lines
MicroRNAs are potent gene expression regulators involved in regulating various biological processes, including host-pathogen interactions. In this...
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Cancer RNome: Evolution and Sustenance
Neoplastic transformation is the result of accumulation of numerous genetic and epigenetic alterations that convert a normal cell into a cancer cell... -
RUNX2 Transcriptional Regulation in Development and Disease
RUNX2, a member of the Runt family of transcription factors, plays important roles in embryonic development to promote osteogenesis and angiogenesis.... -
Implication of the miR-184 and miR-204 Competitive RNA Network in Control of Mouse Secondary Cataract
The high recurrence rate of secondary cataract (SC) is caused by the intrinsic differentiation activity of residual lens epithelial cells after...