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Circ-NUP98 Promotes Lung Adenocarcinoma Development Through Regulating CBX1 by miR-188-3p
Lung cancer has a high morbidity and mortality among malignant tumors, and lung adenocarcinoma (LUAD) is the main type of lung cancer. In recent...
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Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis
BackgroundCircular RNAs (circRNAs) are known to play a crucial role in a variety of malignancies. However, the precise role of circRNAs in cervical...
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Circular RNA circ_0008896 contributes to oxidized low-density lipoprotein-induced aortic endothelial cell injury via targeting miR-188-3p/NOD2 axis
We aimed to investigate the role and mechanism of circ_0008896 in Atherosclerosis (AS) by using oxidized low-density lipoprotein (ox-LDL)-induced...
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Circular RNA 0016142 Knockdown Induces Ferroptosis in Hepatocellular Carcinoma Cells via Modulation of the MicroRNA-188-3p/Glutathione Peroxidase 4 Axis
Hepatocellular carcinoma (HCC) has high incidence and mortality rates, and it is characterized by invasiveness, poor prognosis, and limited treatment...
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Identification of cellular microRNA miR-188-3p with broad-spectrum anti-influenza A virus activity
BackgroundInfluenza A virus (IAV) continues to pose serious threats to public health. The current prophylaxis and therapeutic interventions for IAV...
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Long non-coding RNA LINC00346 promotes pancreatic cancer growth and gemcitabine resistance by sponging miR-188-3p to derepress BRD4 expression
BackgroundLong non-coding RNA LINC00346 has been recently suggested as a prognostic marker in pancreatic cancer. However, its biological function in...
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RETRACTED ARTICLE: TMED3 promotes cell proliferation and motility in breast cancer and is negatively modulated by miR-188-3p
BackgroundThe role of TMED3 involved in cancers has been seldom described, let alone in breast cancer. To explore the clinicopathological...
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Retinoblastoma gene expression profiling based on bioinformatics analysis
BackgroundRetinoblastoma (RB) is frequently occurring malignant tumors that originate in the retina, and their exact cause and development mechanisms...
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Osteosarcoma in a ceRNET perspective
Osteosarcoma (OS) is the most prevalent and fatal type of bone tumor. It is characterized by great heterogeneity of genomic aberrations, mutated...
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Aerobic exercise improves cognitive impairment in mice with type 2 diabetes by regulating the MALAT1/miR-382-3p/BDNF signaling pathway in serum-exosomes
BackgroundIt has been documented that aerobic exercise (AE) has a positive effect on improving cognitive function in type 2 diabetes (T2DM) patients....
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The regulatory role of LncRNA HCG18 in various cancers
As a member of long non-coding RNAs (lncRNAs), LncRNA HLA complex group 18 (HCG18) has recently become the focus of cancer research. As outlined in...
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Exploring the oncogenic potential of circSOD2 in clear cell renal cell carcinoma: a novel positive feedback loop
BackgroundExisting studies have found that circular RNAs (circRNAs) act as sponges for micro RNAs (miRNAs) to control downstream genes. However, the...
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Targeting oncogenic microRNAs from the miR-371~373 and miR-302/367 clusters in malignant germ cell tumours causes growth inhibition through cell cycle disruption
BackgroundMiR-371~373 and miR-302/367 cluster over-expression occurs in all malignant germ cell tumours (GCTs), regardless of age (paediatric/adult),...
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MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers
Although, there is a high rate of good prognosis in early stage head and neck tumors, about half of these tumors are detected in advanced stages with...
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Role of m6A modification in regulating the PI3K/AKT signaling pathway in cancer
The phosphoinositide 3-kinase (PI3K)/AKT signaling pathway plays a crucial role in the pathogenesis of cancer. The dysregulation of this pathway has...
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A New Strategy for the Regulation of Neuroinflammation: Exosomes Derived from Mesenchymal Stem Cells
Neuroinflammation is an important pathogenesis of neurological diseases and causes a series of physiopathological changes, such as abnormal...
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Role of HOXA1-4 in the development of genetic and malignant diseases
The HOXA genes, belonging to the HOX family, encompass 11 members (HOXA1-11) and exert critical functions in early embryonic development, as well as...
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Therapeutic importance and diagnostic function of circRNAs in urological cancers: from metastasis to drug resistance
Circular RNAs (circRNAs) are a member of non-coding RNAs with no ability in encoding proteins and their aberrant dysregulation is observed in...
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Interplay of miR-542, miR-126, miR-143 and miR-26b with PI3K-Akt is a Diagnostic Signal and Putative Regulatory Target in HPV-Positive Cervical Cancer
Human papillomavirus accounts for 99.7% of all cervical cancer cases worldwide. The viral oncoproteins alter normal cell signaling and gene...
