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Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
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Nucleus incertus projections to rat medial septum and entorhinal cortex: rare collateralization and septal-gating of temporal lobe theta rhythm activity
Nucleus incertus (NI) neurons in the pontine tegmentum give rise to ascending forebrain projections and express the neuropeptide relaxin-3 (RLN3)...
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Medial temporal lobe contributions to resting-state networks
The medial temporal lobe (MTL) is a set of interconnected brain regions that have been shown to play a central role in behavior as well as in...
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Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology
Tau neurofibrillary tangle (NFT) pathology in the medial temporal lobe (MTL) is closely linked to neurodegeneration, and is the early pathological...
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Structural Changes in the Brain in Patients with Temporal Lobe Epilepsy and Comorbid Depression
Objectives . To assess the morphological features of brain structures in patients with temporal lobe epilepsy and comorbid depression. Materials and...
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Downstream effects of polypathology on neurodegeneration of medial temporal lobe subregions
The medial temporal lobe (MTL) is a nidus for neurodegenerative pathologies and therefore an important region in which to study polypathology. We...
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Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy
Interneuron loss/dysfunction contributes to spontaneous recurrent seizures (SRS) in chronic temporal lobe epilepsy (TLE), and interneuron grafting...
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Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)
Synaptic vesicle glycoprotein-2 (SV2) is a family of proteins consisting of SV2A, SV2B, and SV2C. This protein family has attracted attention in...
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Characteristics of Resting State Functional Connectivity of the Brain in Patients with Lateralized Damage to the Mediobasal Areas of the Temporal Lobe (fMRI and EEG data)
Structural and functional support of executive functions, currently under active investigation, is largely associated with the prefrontal and...
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Anatomy of the Limbic System and Surgery for Medial Temporal Lesions
The limbic system is phylogenetically the oldest and functionally the most complex and least understood parts of the human brain [1]. The limbic...
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Phase-Amplitude Coupling and Phase Synchronization Between Medial Temporal, Frontal and Posterior Brain Regions Support Episodic Autobiographical Memory Recall
Episodic autobiographical memory (EAM) is a complex cognitive function that emerges from the coordination of specific and distant brain regions....
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Investigating the mechanism of antiepileptogenic effect of apigenin in kainate temporal lobe epilepsy: possible role of mTOR
Clarifying the underlying mechanisms of epileptogenesis is important in preventing the progression of chronic epilepsy. In epilepsy, the mTOR...
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How to Build Temporal Lobes
In this chapter we must create another sense organ; our half-formed brain can see and smell, but cannot hear, and relatedly has no language or...
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Non-invasive temporal interference electrical stimulation of the human hippocampus
Deep brain stimulation (DBS) via implanted electrodes is used worldwide to treat patients with severe neurological and psychiatric disorders....
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Visual Selective Attention P300 Source in Frontal-Parietal Lobe: ERP and fMRI Study
Visual selective attention can be achieved into bottom-up and top-down attention. Different selective attention tasks involve different attention...
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Spatial Distribution of Parvalbumin-Positive Fibers in the Mouse Brain and Their Alterations in Mouse Models of Temporal Lobe Epilepsy and Parkinson’s Disease
Parvalbumin interneurons belong to the major types of GABAergic interneurons. Although the distribution and pathological alterations of parvalbumin...
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The parietal lobe evolution and the emergence of material culture in the human genus
Traditional and new disciplines converge in suggesting that the parietal lobe underwent a considerable expansion during human evolution. Through the...
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Neurophysiological Aspects of Multiple Hippocampal Transection in Temporal Epilepsy
Objectives. To establish a correlation between intraoperative electrocorticography data and seizure monitoring after multiple hippocampal transection...
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A Comparison of Three Brain Atlases for Temporal Lobe Epilepsy Prediction
PurposeAn accurate and reliable brain atlas, as the role of navigation, should be effective and vital to differentiate the patients with temporal...
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The Glycolysis Inhibitor 2-Deoxy-d-Glucose Exerts Different Neuronal Effects at Circuit and Cellular Levels, Partially Reverses Behavioral Alterations and does not Prevent NADPH Diaphorase Activity Reduction in the Intrahippocampal Kainic Acid Model of Temporal Lobe Epilepsy
Temporal lobe epilepsy is the most drug-resistant type with the highest incidence among the other focal epilepsies. Metabolic manipulations are of...
