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Revision of NMR assignment for Morin-3-O-glucoside and microbial production of Morin-2’-O-glucoside
Morin is a flavonol having 2’,4’-dihydroxy group on B-ring identified especially in Moraceae plants. While morin is widely known, its glycosides are...
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Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model
Cyanidin-3-O-glucoside (C3G) is a natural anthocyanin with antioxidant, anti-inflammatory, and antitumor properties. However, as the effects of C3G...
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Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway
BackgroundFerroptosis, which is characterized by lipid peroxidation and iron accumulation, is closely associated with the pathogenesis of acute renal...
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Lanceolanone A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activation
The MeOH extract of the flower heads of Coreopsis lanceolata L. (Asteraceae) exhibited aldose reductase (AR) inhibitory activity (IC 50 8.36 µg/mL)....
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Genetic engineering of novel yellow color african violet (Saintpaulia ionantha) produced by accumulation of Aureusidin 6-O-glucoside
BackgroundFlower color is one of the main characteristics of ornamental plants. Aurones are light yellow flavonoids produced in the petals of a...
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Cyanidin-3-O-Glucoside Regulates the M1/M2 Polarization of Microglia via PPARγ and Aβ42 Phagocytosis Through TREM2 in an Alzheimer’s Disease Model
Microglial polarization plays an essential role in the progression and regression of neurodegenerative disorders. Cyanidin-3- O -glucoside (C3G), a...
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Health benefits of cyanidin-3-glucoside as a potent modulator of Nrf2-mediated oxidative stress
Berries are natural sources of anthocyanins, especially cyanidin-3-glucoside (C3G), and exhibit significant antioxidant, antidiabetic,...
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Utility of the combination of hederagenin glucoside saponins and chromane hydrazone in the topical treatment of canine cutaneous leishmaniasis. An observational study
Canine cutaneous leishmaniasis (CCL) is an emerging zoonotic infection endemic in several countries of the world. Due to variable response to therapy...
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Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica
Two new compounds, thannilignan 9- O -β-glucoside ( 1 ) and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative ( 2 ), and seven known compounds were...
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Panaxindole, a novel indole alkaloid N-glucoside from the leaves of Panax vietnamensis Ha et Grushv. (Vietnamese ginseng)
Vietnamese ginseng ( Panax vietnamensis Ha and Grushv., Araliaceae) is indigenous in the central highlands of Vietnam and the southernmost...
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Metabolite profiling of Drynariae Rhizoma using 1H NMR and HPLC coupled with multivariate statistical analysis
Drynariae Rhizoma has been used to treat bone diseases and kidney deficiency in traditional medicine. Recently its aqueous extract was reported to...
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In silico studies on the phytochemical components of Lagenaria siceraria targeting aromatase receptors against breast cancer
In India, breast cancer is the most common cause of mortality for women and has the potential to spread to other body organs. As a transcription...
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Naturally occurring small molecules with dual effect upon inflammatory signaling pathways and endoplasmic reticulum stress response
The endoplasmic reticulum (ER) is determinant to maintain cellular proteostasis. Upon unresolved ER stress, this organelle activates the unfolded...
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Investigation of age-related differences in toxicokinetic processes of deoxynivalenol and deoxynivalenol-3-glucoside in weaned piglets
Age-related differences in toxicokinetic processes of deoxynivalenol (DON) and deoxynivalenol-3-glucoside (DON3G) were studied. DON3G [55.7 µg/kg...
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Apoptotic and antimetastatic effect of cucurbitacins in cancer: recent trends and advancement
The Cucurbitaceae family produces a class of secondary metabolites known as cucurbitacins. The eight cucurbitacin subunits are cucurbitacin B, D, E,...
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Flavonoid as possible therapeutic targets against COVID-19: a sco** review of in silico studies
ObjectivesThis sco** review aims to present flavonoid compounds’ promising effects and possible mechanisms of action on potential therapeutic...
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Anthraquinones from Rhubarb as Potential Inhibitors of Trimethylamine (TMA)-Lyase for Alzheimer’s disease
AbstractAlzheimer’s disease (AD) is a common neurodegenerative disease with severe deficits in memory and cognition that seriously affects the...
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Unilateral intranigral administration of β-sitosterol β-D-glucoside triggers pathological α-synuclein spreading and bilateral nigrostriatal dopaminergic neurodegeneration in the rat
The spreading and accumulation of α-synuclein and dopaminergic neurodegeneration, two hallmarks of Parkinson’s disease (PD), have been faithfully...
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Matricaria chamomilla L.
Matricaria chamomilla is an annual plant and its stem is glabrous, branched, erect, and smooth and it is a well-known medical plant extensively...