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Increased circulating Tfh to Tfr ratio in chronic renal allograft dysfunction: a pilot study
BackgroundT follicular helper (Tfh) cells play a control role in contribution of B cell differentiation and antibody production. T follicular...
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Rapamycin Controls Lymphoproliferation and Reverses T-Cell Responses in a Patient with a Novel STIM1 Loss-of-Function Deletion
PurposeDeficiency of stromal interaction molecule 1 (STIM1) results in combined immunodeficiency accompanied by extra-immunological findings like...
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Evaluation of Clinical and Immunological Alterations Associated with ICF Syndrome
PurposeImmunodeficiency with centromeric instability and facial anomalies (ICF) syndrome is a rare autosomal recessive combined immunodeficiency. The...
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PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine
Anti-programmed death-1 (anti-PD-1) immunotherapy reinvigorates CD8 T cell responses in patients with cancer but PD-1 is also expressed by other...
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Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases
T follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody...
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The link between circulating follicular helper T cells and autoimmunity
Follicular helper T (T FH ) cells provide help to B cells, supporting the formation of germinal centres that allow affinity maturation of antibody...
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Temporal correlations in modulated evoked responses in the visual cortical cells of the cat
We analysed evoked responses recorded from 97 cells in the visual cortex of 4 adult cats and 8 kittens, stimulated by a drifting sinusoidal grating....