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Benign splenic lesions in BAP1-tumor predisposition syndrome: a case series
BAP1-Tumor Predisposition Syndrome (TPDS) is caused by germline variants in BAP1 and predisposes to solid tumors. After observation of a...
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A comparative study on ctDNA and tumor DNA mutations in lung cancer and benign cases with a high number of CTCs and CTECs
BackgroundLiquid biopsy provides a non-invasive approach that enables detecting circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs)...
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Benign Glioma
BenignBenign gliomaGliomas broadly refers to a heterogeneousHeterogeneous group of slow-growing glial tumors with low proliferative rates and a more...
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Benign tumors and non-melanoma skin cancers in patients with Fanconi anemia
Fanconi anemia (FA) is an inherited bone marrow failure syndrome (IBMFS) characterized by pathogenic variants in the FA/BRCA DNA repair pathway...
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Differentiation of benign and metastatic lymph nodes in soft tissue sarcoma
Lymph node metastasis (LNM) occurs in less than 5% of soft tissue sarcoma (STS) patients and indicates an aggressive course of disease. Suspicious...
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Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease
Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an...
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Benign and Malignant Tumors of the Pineal Region
PinealPineal region tumors fall into five broad categories: benign pineal region tumorsBenign Pineal Region Tumors, glial tumors, papillaryPapillary...
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An effective convolutional neural network for classification of benign and malignant breast and thyroid tumors from ultrasound images
Breast and thyroid cancers are the two most common cancers among women worldwide. The early clinical diagnosis of breast and thyroid cancers often...
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Tumor Microenvironment
In this chapter, we will learn that the tumor microenvironment is a stroma of normal cells supporting cancer cells. Tumors act like parasites that...
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Benign Spinal Tumors
BenignBenign spinal intraduralIntradural tumors are relatively rare and include intramedullaryIntramedullary tumors with a favorable...
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Aquaporins in Tumor
Recent researches have demonstrated that aquaporins (AQPs), including water-selective channels, aquaglyceroporins and superaquaporins, are generally...
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Construction of a Diagnostic Model for Distinguishing Benign or Malignant Bone Cancer by Mining miRNA Expression Data
Bone tumor is a kind of rare cancer, the location of which is mainly in bone tissue as well as cartilage tissue. Bone tumor is mainly classified into...
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Rate of benign histology after resection of suspected renal cell carcinoma: multicenter comparison between Korea and the United States
BackgroundIn the United States, the rate of benign histology among resected renal tumors suspected to be malignant is increasing. We evaluated the...
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Humoral immune response to tumor-associated antigen Ubiquilin 1 (UBQLN1) and its tumor-promoting potential in lung cancer
BackgroundThis study aims to investigate the expression of UBQLN1 in lung cancer (LC) tissue and the diagnostic capability of autoantibody to UBQLN1...
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Classification of benign and malignant parotid tumors based on CT images combined with stack generalization model
Parotid tumors are among the most prevalent tumors in otolaryngology, and malignant parotid tumors are one of the main causes of facial paralysis in...
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Serum lncRNA THRIL predicts benign and malignant pulmonary nodules and promotes the progression of pulmonary malignancies
BackgroundThis project aimed to research the significance of THRIL in the diagnosis of benign and malignant solitary pulmonary nodules (SPNs) and to...
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Differential diagnosis of benign and malignant patchy ground-glass opacity by thin-section computed tomography
BackgroundPrevious studies confirmed that ground-glass nodules (GGNs) with certain CT manifestations had a higher probability of malignancy. However,...
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Tumor Suppressor Genes
Tumor suppressors are the second major type of cancer genes. In contrast to oncogenes, tumor suppressor genes have to undergo loss of function to...
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Human parvovirus B19 infection in malignant and benign tissue specimens of different head and neck anatomical subsites
BackgroundThe role of human parvovirus B19 (B19V) infection in malignant and benign lesions such as head and neck squamous cell carcinomas (HNSCCs)...
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Benign and Malignant Tumors of the Pituitary Gland
Pituitary glandPituitary gland tumors represent approximately 10–15% of all brain tumorsBrain tumor and the most common neoplasmsNeoplasm of the...