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Social Anhedonia: (f)MRI Studies
Anhedonia, particularly social anhedonia, is an important psychopathological symptom which plays a key role in the development of depression and...
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Anhedonia and Suicide
Suicide is a leading cause of death, and presently, there is no definitive clinical indicator of future suicide behaviors. Anhedonia, a...
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Anhedonia in Neurodegenerative Diseases
Neurodegenerative diseases are increasingly recognised to be an important cause of brain disorders, particularly in late age. Associated with a wide...
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Psychological Treatments for Anhedonia
Anhedonia, a loss of interest or pleasure in activities, is a transdiagnostic symptom that characterizes many individuals suffering from depression...
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Anhedonia in Schizophrenia
Anhedonia has long been considered a cardinal symptom of schizophrenia. This symptom is strongly associated with poor functional outcome, and limited...
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Anhedonia in Eating Disorders
Anhedonia is frequently observed among individuals with eating disorders (ED), though its relevance to ED pathology and clinical outcomes remain...
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Anhedonia in Anxiety Disorders
Humans, like other animals, are fundamentally motivated to pursue rewarding outcomes and avoid aversive ones. Anxiety disorders are conceptualized,...
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Anhedonia: Preclinical, Translational, and Clinical Integration
Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use...
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Circuit-Targeted Neuromodulation for Anhedonia
Despite the prevalence of anhedonia across multiple psychiatric disorders, its relevance to treatment selection and prognostication can be unclear...
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Pharmacological Treatments for Anhedonia
Anhedonia – the reduced ability to experience or respond to pleasure – is an important symptom domain for many psychiatric disorders. It is...
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Anhedonia in Nicotine Dependence
Prior findings indicate that trait anhedonia enhances the likelihood of becoming a tobacco smoker, and preliminary evidence suggests that smoking...
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Understanding Anhedonia from a Genomic Perspective
Anhedonia, or the decreased ability to experience pleasure, is a cardinal symptom of major depression that commonly occurs within other forms of...
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Developmental Trajectories of Anhedonia in Preclinical Models
This chapter discusses how the complex concept of anhedonia can be operationalized and studied in preclinical models. It provides information about...
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Anhedonia in Depression and Bipolar Disorder
Anhedonia is a hallmark feature of depression and is highly prevalent among individuals with mood disorders. The history and neurobiology of...
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Anhedonia in Depression: Neurobiological and Genetic Aspects
Anhedonia is a pathogenetically important clinical phenotype and a potential endophenotype for depressive symptoms with very high contributions from...
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Probabilistic Reinforcement Learning and Anhedonia
Despite the prominence of anhedonic symptoms associated with diverse neuropsychiatric conditions, there are currently no approved therapeutics...
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Anticipation: An Essential Feature of Anhedonia
The following essay addresses the evolution of the term “anhedonia” as a key construct in biological psychiatry, especially as it pertains to...
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Origins of Anhedonia in Childhood and Adolescence
Anhedonia reflects a reduced ability to engage in previously pleasurable activities and has been reported in children as young as 3 years of age. It...
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Pleasure, Reward Value, Prediction Error and Anhedonia
In order to develop effective treatments for anhedonia we need to understand its underlying neurobiological mechanisms. Anhedonia is conceptually...
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Clinical and Preclinical Assessments of Anhedonia in Psychiatric Disorders
Anhedonia is a prevalent symptom across many psychiatric disorders. The contemporary scope of anhedonia across various models includes interest,...