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Using DeepLab v3 + -based semantic segmentation to evaluate platelet activation
This research used DeepLab v3 + -based semantic segmentation to automatically evaluate the platelet activation process and count the number of...
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Development of Inspired Therapeutics Pediatric VAD: Computational Analysis and Characterization of VAD V3
PurposePediatric heart failure patients remain in critical need of a dedicated mechanical circulatory support (MCS) solution as development efforts...
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Co-expression and clinical utility of AR-FL and AR splice variants AR-V3, AR-V7 and AR-V9 in prostate cancer
BackgroundAndrogen receptor (AR) splice variants (AR-Vs) have been discussed as a biomarker in prostate cancer (PC). However, some reports question...
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Metasequencing of V3-V4 Variable Regions of 16S rRNA Gene in Opportunistic Microbiota and Gut Biocenosis in Obese Adolescents
Opportunistic microorganisms in the gut biocenosis were studied in adolescents with normal body weight and obesity (patients consulted at the...
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Association of VNTR Polymorphism of the AS3MT Gene with the Risk of Schizophrenia
The AS3MT gene encodes arsenic(III) methyltransferase. VNTR polymorphism of the AS3MT gene is characteristic only for the human genome. It is...
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Somatotopic organization of the ventral nuclear group of the dorsal thalamus: deep brain stimulation for neuropathic pain reveals new insights into the facial homunculus
Deep Brain Stimulation (DBS) is an experimental treatment for medication-refractory neuropathic pain. The ventral posteromedial (VPM) and ventral...
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Prediction of treatment response in major depressive disorder using a hybrid of convolutional recurrent deep neural networks and effective connectivity based on EEG signal
In this study, we have developed a novel method based on deep learning and brain effective connectivity to classify responders and non-responders to...
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Effect of Entamoeba histolytica infection on gut microbial diversity and composition in diarrheal patients from New Delhi
During amoebiasis, colonization of the gut by Entamoeba histolytica can lead to alterations of the host microbiota. In this study, we have compared...
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Differences in neutralizing antibody sensitivities and envelope characteristics indicate distinct antigenic properties of Nigerian HIV-1 subtype G and CRF02_AG
The magnitude of the HIV-1 epidemic in Nigeria is second only to the subtype C epidemic in South Africa, yet the subtypes prevalent in Nigeria...
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In Silico Prediction of Pharmacokinetic Profile for Human Oral Drug Candidates Which Lack Clinical Pharmacokinetic Experiment Data
Backgrounds and ObjectivesIn silico methods which can generate high-quality physiologically based pharmacokinetic (PBPK) models for arbitrary drug...
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Activity in primate visual cortex is minimally driven by spontaneous movements
Organisms process sensory information in the context of their own moving bodies, an idea referred to as embodiment. This idea is important for...
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EEG-based schizophrenia detection using fusion of effective connectivity maps and convolutional neural networks with transfer learning
Schizophrenia (SZ) is a serious mental disorder that can mainly be distinguished by symptoms including delusions and hallucinations. This mental...
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Long-term safety and efficacy of open-label nabilone on sleep and pain in Parkinson´s Disease
The synthetic tetrahydrocannabinol-analog nabilone improved non-motor symptoms (NMS) in Parkinson’s disease (PD) patients in a placebo-controlled,...
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Alpha Diversity Indices as Indicators of the Variability of Gut Microbiota in Obese Adolescents of Different Ethnicities
We compared alpha diversity indices of the intestinal microbiota in adolescents with obesity and normal body weight, taking into account their...
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The Dual Role of HIV-1 gp120 V3 Loop-Induced Autophagy in the Survival and Apoptosis of the Primary Rat Hippocampal Neurons
HIV-1 gp120, an important subunit of the envelope spikes that decorate the surface of virions, is known to play a vital role in neuronal injury...
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Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice
Integrase-strand-transfer inhibitors (INSTIs) are known to rapidly reduce HIV-1 plasma viral load, replication cycles, and new viral integrations,...
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Convolutional neural network-based magnetic resonance image differentiation of filum terminale ependymomas from schwannomas
PurposePreoperative diagnosis of filum terminale ependymomas (FTEs) versus schwannomas is difficult but essential for surgical planning and...
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GeneXpert MTB/RIF Ultra performance to detect uncommon rpoB mutations in Mycobacterium tuberculosis
ObjectiveTo investigate the performance of GeneXpert MTB/RIF Ultra to accurately detect rifampicin resistance for less common rpoB mutations that...
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Effects of agricultural pesticides on the susceptibility and fitness of malaria vectors in rural south-eastern Tanzania
BackgroundAgricultural pesticides may exert strong selection pressures on malaria vectors during the aquatic life stages and may contribute to...
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Association of FTO Polymorphism with GDM: A Meta-Analysis and Trial Sequential Analysis
AbstractThe fat mass and obesity (FTO) gene is linked to lipid and carbohydrate metabolism, and insulin sensitivity is thought to play a role in the...
