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Detection, Structure and Polymorphism of Nucleic Acids
Detection and characterization of DNA and RNA is needed in many areas, which include all branches of biology, medicine, environmental control and...
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The effect of FTO gene rs9939609 polymorphism on the association between colorectal cancer and different types of dietary fat intake: a case-control study
BackgroundColorectal cancer (CRC) is one of the most common cancers in the world. Some dietary factors such as fat intake have been identified as the...
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Polymorphism and varying selection within the MHC class I of four Anas species
Ducks (Anatidae) are often vectors for the spread of pathogens because of their long-distance migrations. These migrations also expose ducks to a...
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The negative effect of G1958A polymorphism on MTHFD1 protein stability and HCC growth
PurposeMethylenetetrahydrofolate dehydrogenase (MTHFD1), a key enzyme on the folate pathway, has been implicated in the tumor development of distinct...
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NPC1L1 rs217434 A > G as a Novel Single Nucleotide Polymorphism Related to Dyslipidemia in a Korean Population
A relationship between cholesterol levels and Niemann-Pick C1-Like 1 ( NPC1L1 ) polymorphisms in diverse populations was found in previous studies....
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Characterization and genetic diversity of MHC class II DRB genes in the Arabian camel (Camelus dromedarius)
This study investigated the MHC DRB genes in the Arabian camel ( Camelus dromedarius ). The results revealed the presence of — at least — two...
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Interaction between caveolin-1 polymorphism and dietary fat quality indexes on visceral adiposity index (VAI) and body adiposity index (BAI) among overweight and obese women: a cross-sectional study
Background and aimsCaveolin-1 (CAV-1) in adipocyte tissue and other body parts possesses numerous biological functions. In the present study, we...
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A significant association between CXCL10 -1447 A > G and IL18 -607 C > A gene polymorphism with human T-cell lymphotropic virus type 1 associated myelopathy/tropical spastic paraparesis (HAM-TSP), a case-control report from city of Mashhad, Iran
Human T-cell lymphotropic virus type 1 (HTLV-1) is the first isolated retrovirus from humans, and 2–3% of infected individuals suffer from HTLV-1...
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Patterns of evolution in MHC class II DQA and DQB exon 2 genes of Alpine mountain hares, Lepus timidus varronis, and sympatric and parapatric brown hares, L. europaeus, from Switzerland
In natural populations, hybridization is known to occur between a wide range of species. However, its evolutionary significance is less clear. Genes...
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Diabetes and Cardiovascular Disorder
Diabetes mellitus especially type 2 diabetes mellitus (T2DM) is becoming more common at an alarming rate, resulting in increased disability,...
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Association of Genetic Polymorphisms in Long Noncoding RNA HOTTIP with Risk of Idiopathic Recurrent Spontaneous Abortion
The clustered homeobox gene family known as the Hox family plays a fundamental role in the morphogenesis of the vertebrate’s embryo. A long noncoding...
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Global allele polymorphism indicates a high rate of allele genesis at a locus under balancing selection
When selection favours rare alleles over common ones (balancing selection in the form of negative frequency-dependent selection), a locus may...
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Pleiotropy, epistasis and the genetic architecture of quantitative traits
Pleiotropy (whereby one genetic polymorphism affects multiple traits) and epistasis (whereby non-linear interactions between genetic polymorphisms...
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Current advances in primate genomics: novel approaches for understanding evolution and disease
Primate genomics holds the key to understanding fundamental aspects of human evolution and disease. However, genetic diversity and functional...
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Individual copy number variation and extensive diversity between major MHC-DAB1 allelic lineages in the European bitterling
Polymorphism of the major histocompatibility complex (MHC), DAB1 gene was characterized for the first time in the European bitterling ( Rhodeus amarus )...
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Cannabinoids and Endocannabinoids
The intoxicating and medicinal properties of cannabis have been known since the human species domesticated the plant, at least 11,000 years before...
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Cannabinoids and Endocannabinoids
The intoxicating and medicinal properties of cannabis have been known since the human species domesticated the plant, at least 11,000 years before...
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Bona fide atypical scrapie faithfully reproduced for the first time in a rodent model
Atypical Scrapie, which is not linked to epidemics, is assumed to be an idiopathic spontaneous prion disease in small ruminants. Therefore, its...
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Intra-specific copy number variation of MHC class II genes in the Siamese fighting fish
Duplicates of genes for major histocompatibility complex (MHC) molecules can be subjected to selection independently and vary markedly in their...
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Blending, Hydrogenation , Fractionation and Interesterification Processing
The lipid industry is constantly researching and develo** techniques to improve the quality, stability, nutrition, and technological features of...