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In-depth metaproteomics analysis of tongue coating for gastric cancer: a multicenter diagnostic research study
BackgroundOur previous study revealed marked differences in tongue images between individuals with gastric cancer and those without gastric cancer....
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Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment...
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Deep Upscale U-Net for automatic tongue segmentation
AbstractIn a treatment or diagnosis related to oral health conditions such as oral cancer and oropharyngeal cancer, an investigation of tongue’s...
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Genetic Alterations and Microbial Dysbiosis Underlie Lymph Node Metastasis in Tongue Cancer
Oral cancer presents a significant clinical challenge due to the presence of hidden lymph node metastases, which greatly influence treatment...
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Inducible TgfbR1 and Pten deletion in a model of tongue carcinogenesis and chemoprevention
Head and neck squamous cell carcinoma (HNSCC) is a significant public health problem, with a need for novel approaches to chemoprevention and...
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Tertiary lymphoid structures associate with improved survival in early oral tongue cancer
BackgroundThe clinical significance of tertiary lymphoid structures (TLSs) is not well-documented in early oral tongue squamous cell carcinoma...
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Integrated bioinformatics analysis of SEMA3C in tongue squamous cell carcinoma using machine-learning strategies
Tongue squamous cell carcinoma (TSCC) is an aggressive oral cancer with a high incidence of metastasis and poor prognosis. We aim to identify and...
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Negative prognostic behaviour of PD-L1 expression in tongue and larynx squamous cell carcinoma and its significant predictive power in combination with PD-1 expression on TILs
BackgroundBiomarkers that can predict outcome will improve the efficacy of treatment for HNSCC patients. In this regard, we retrospectively evaluated...
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The prognostic role of single cell invasion and nuclear diameter in early oral tongue squamous cell carcinoma
BackgroundThe clinical significance of single cell invasion and large nuclear diameter is not well documented in early-stage oral tongue squamous...
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Single-Response Electronic Tongue and Machine Learning Enable the Multidetermination of Extracellular Vesicle Biomarkers for Cancer Diagnostics Without Recognition Elements
Platforms based on impedimetric electronic tongue (nonselective sensor) and machine learning are promising to bring disease screening biosensors into...
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Species composition and overall diversity are significantly correlated between the tongue coating and gastric fluid microbiomes in gastritis patients
BackgroundIn traditional Chinese medicine, it is believed that the “tongue coating is produced by fumigation of stomach gas”, and that tongue coating...
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Molecular Biomarkers of Oral Cancer
The number of cases of oral cancer and the number of deaths has been increasing in recent years. Since the oral cavity has an important role in...
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Targeting of 3D oral cancer spheroids by αVβ6 integrin using near-infrared peptide-conjugated IRDye 680
BackgroundIn the treatment of oral cavity cancer, margin status is one of the most critical prognostic factors. Positive margins are associated with...
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Risk of subsequent primary oral cancer in a cohort of 69,460 5-year survivors of childhood and adolescent cancer in Europe: the PanCareSurFup study
BackgroundSurvivors of childhood cancer are at risk of subsequent primary malignant neoplasms (SPNs), but the risk for rarer types of SPNs, such as...
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Molecular Landscape of Oral Cancer in Young Adults
AbstractOral cancer (OC) is the most common cancer of the head and neck. Tongue cancer (TC) is the most frequently diagnosed form of OC and is...
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The Microenvironment of Tongue Cancer
Cancer cells interact with and remodel the surrounding microenvironment. An increasing number of studies focus on tongue tumor microenvironment (TME)...
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Synbiotics in Buccal Cancer
Cancer is a lethal disorder with high clinical consequence which ultimately leads to death. Cancer of buccal cavity is coming under the 11th most...
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Oral cancer patients experience mechanical and chemical sensitivity at the site of the cancer
IntroductionOral cancer patients suffer severe chronic and mechanically-induced pain at the site of the cancer. Our clinical experience is that oral...
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Cancer Statistics: Geographical and Racial Disparities
Cancer leads to millions of morbidities and mortalities throughout the world, annually. There are well-established discrepancies in cancer incidence...