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Toxische und essentielle Schwermetalle
Schwermetalle sind unter uneinheitlichen Definitionen zusammengefasste Metalle, deren Dichte oder Atommasse einen bestimmten Wert übersteigt....
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Thermosensitive nasal in situ gelling systems of rufinamide formulated using modified tamarind seed xyloglucan for direct nose-to-brain delivery: design, physical characterization, and in vivo evaluation
PurposeRufinamide is an anti-epileptic drug approved for use in children ≥ 4 years of age and in adults. It is marketed as Banzel in the USA. In...
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Early Clinical Trials
Studies in volunteers are most important in the research and development of a medicinal product or, as defined by the US Food and Drug Administration...
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Early Clinical Trials
Studies in volunteers are most important in the research and development of a medicinal product or, as defined by the US Food and Drug Administration...
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Solid Lipid Nanoparticles for the Management of Allergic Airway Diseases
The allergic airway diseases comprise both allergic rhinitis and asthma which are amongst the top three ailments of the twenty-first century...
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Prohibition and Restrictions in Regulatory Toxicology
The last century has seen huge advances in chemistry. It has been estimated that more than 300,000 substances are on the market. It is hardly...
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Prohibition and Restrictions in Regulatory Toxicology
The last century has seen huge advances in chemistry. It has been estimated that more than 300,000 substances are on the market. It is hardly...
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Historical Progression from Nerve Tissue-Based Rabies Vaccines to Recombinant Biologics for Humans and Companion Animals
Annually, vaccines against infectious agents prevent countless cases of human misery and death. One of the first vaccines that was developed and...
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A guide to vaccinology: from basic principles to new developments
Immunization is a cornerstone of public health policy and is demonstrably highly cost-effective when used to protect child health. Although it could...
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Topical Ophthalmic Dosage Form Development: Key Components and Critical Quality Attributes
General principles for the development of a topical ophthalmic dosage form intended for application to ocular structures are discussed. Topical...
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History of Rabies and Rabies Vaccines
Lyssaviruses continue to evolve and pose threats to humans, domestic animals, and wildlife. As a fatal disease of zoonotic importance, rabies is...
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Letter W
Waelsch’s disease (see Reiter’s syndrome Nongonococcal urethritis or Waelsch urethritis) is a part of now a familiar triad—namely, the conjunctiva of...
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Identifying Neural Progenitor Cells in the Adult Human Brain
The discovery, in 1998, that the adult human brain contains at least two populations of progenitor cells and that progenitor cells are upregulated in...
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Anti-coronavirus vaccines will not accelerate the transition of humanity to a non-pandemic period, but the pandemic will take fewer victims
The vaccination rate worldwide has reached enormous proportions, and it is likely that at least 75% of the world's population will be vaccinated. The...
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Sirtuins as molecular targets, mediators, and protective agents in metal-induced toxicity
Metal dyshomeostasis, and especially overexposure, is known to cause adverse health effects due to modulation of a variety of metabolic pathways. An...
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The Challenges with Canine Giardia
This chapter reviews the prevalence of Giardia and Giardia Assemblages in people and dogs and the risks that dogs may present as sources of human...
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The embodiment of the strategy of “using active chemicals as excipients” in compound preparation
Background“Using active chemicals as excipients” refers to a preparation strategy. It makes use of the drugs owning the special physical and chemical...
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Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a...
