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  1. Spectrofluorimetric Protocol for Estimation of Commonly Used Antispasmodic Drotaverine. Fluorescence Quenching Study

    A fast, simple, accurate, precise, and cheap fluorimetric protocol has been proposed for analysis of a phosphodiesterase-IV inhibitor, namely...

    Sayed M. Derayea, Nihad A. Mahmoud, ... Tamer Z. Attia in Journal of Fluorescence
    Article Open access 06 November 2023
  2. An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders

    Background

    Induced pluripotent stem cell-derived microglia (iMGL) represent an excellent tool in studying microglial function in health and disease....

    Marie-France Dorion, Diana Casas, ... Luke M. Healy in Molecular Neurodegeneration
    Article Open access 05 April 2024
  3. Elements of Clinical Trial Protocol Design

    Clinical trials are conducted for many reasons, including to determine whether a new drug is safe and effective for a therapeutic use. A clinical...
    Chapter 2023
  4. Randomized controlled phase III trial to investigate superiority of robot-assisted gastrectomy over laparoscopic gastrectomy for clinical stage T1-4aN0-3 gastric cancer patients (JCOG1907, MONA LISA study): a study protocol

    Background

    Laparoscopic gastrectomy (LG) is considered a standard treatment for clinical stage I gastric cancer. Nevertheless, LG has some drawbacks,...

    Rie Makuuchi, Masanori Terashima, ... Takaki Yoshikawa in BMC Cancer
    Article Open access 17 October 2023
  5. Process evaluation protocol plan for a home-based physical activity intervention versus educational intervention for persistent taxane-induced peripheral neuropathy (B-HAPI study): a randomized controlled trial

    Background

    Evaluation publications typically summarize the results of studies to demonstrate the effectiveness of an intervention, but little is...

    Samia Valeria Ozorio Dutra, Lauren Schwab, ... Constance Visovsky in BMC Cancer
    Article Open access 27 June 2024
  6. Protocol to Study West Nile Virus Infection in Brain Slices In Vitro

    Ex vivo slice cultures of the brain tissue can maintain the cytoarchitecture of the central nervous system (CNS), which allows a thorough...
    Parminder J. S. Vig in West Nile Virus
    Protocol 2023
  7. Priming constraint-induced movement therapy with intermittent theta burst stimulation to enhance upper extremity recovery in patients with stroke: protocol for a randomized controlled study

    Background

    The treatments based on motor control and motor learning principles have gained popularity in the last 20 years, as well as non-invasive...

    Esma Nur Kolbaşı, Burcu Ersoz Huseyinsinoglu, ... Aysun Soysal in Acta Neurologica Belgica
    Article 08 February 2024
  8. The effect of physical exercise during radiotherapy on physical performance in patients with head and neck cancer: a trial within cohorts study protocol, the vital study

    Background

    During the last decade, twelve studies have been published investigating physical exercise interventions (PEIs) in patients with head and...

    Yvette Kriellaars, Jorine Ariane Vermaire, ... Caroline Margina Speksnijder in BMC Cancer
    Article Open access 01 April 2024
  9. The Implementation of an Integrated Oral Care Protocol for Pediatric Cancer Patients: a Qualitative Study

    Aim

    In this study, we evaluated the impact of an integrated oral care protocol for pediatric patients undergoing antineoplastic treatment from the...

    Isabella Lima Arrais Ribeiro, Maria do Carmo Gullaci Guimarães Caccia-Bava, ... Ana Maria Gondim Valença in Journal of Cancer Education
    Article 27 August 2022
  10. HPV testing in Polish population-based cervical cancer screening programme (HIPPO project)—study protocol of a randomised healthcare policy trial

    Background

    An Organised Cervical Cancer Screening Programme (OCCSP) was started in Poland in 2006/2007. Each woman aged 25 to 59 is eligible for a...

    Patrycja Glinska, Katarzyna Komerska, ... Andrzej Nowakowski in BMC Cancer
    Article Open access 17 November 2023
  11. Protocol of the RACB study: a multicenter, single-arm, prospective study to evaluate the efficacy of resection of initially unresectable hepatocellular carcinoma with atezolizumab combined with bevacizumab

    Background

    Although the standard therapy for advanced-stage hepatocellular carcinoma (HCC) is systemic chemotherapy, the combination of atezolizumab...

    Masayuki Okuno, Takamichi Ishii, ... Etsuro Hatano in BMC Cancer
    Article Open access 21 August 2023
  12. Multidisciplinary treatment protocol for ischiatic, sacral, trochanteric or other pressure injuries in people with spinal cord injury: a retrospective cohort study

    Study design

    Retrospective cohort study Objectives: to describe the incidence and the associated risk factors of post-surgical complications and...

    Rossella Sgarzani, Elisa Maietti, ... Luca Negosanti in Spinal Cord
    Article 23 December 2022
  13. Personalised exercise rehabilitation in cancer survivorship: the percs triage and referral system study protocol

    Background

    To effectively embed exercise rehabilitation in cancer survivorship care, a co-ordinated system of acute and community exercise...

    Louise Brennan, Grainne Sheill, ... Emer M. Guinan in BMC Cancer
    Article Open access 23 April 2024
  14. Using antenatal care as a platform for malaria surveillance data collection: study protocol

    Background

    While many malaria-endemic countries have health management information systems that can measure and report malaria trends in a timely...

    Julie R. Gutman, Julia Nanteza Mwesigwa, ... Molly Robertson in Malaria Journal
    Article Open access 17 March 2023
  15. Vaginal CO2 laser therapy for genitourinary syndrome in breast cancer survivors—VagLaser study protocol: a randomized blinded, placebo-controlled trial

    Background

    Vaginal CO 2 laser therapy is a new treatment option for genitourinary syndrome of menopause. Its potential is particularly interesting in...

    Sine Jacobsen, Marianne Glavind-Kristensen, ... Pinar Bor in BMC Cancer
    Article Open access 29 November 2023
  16. The Protocol of Ultrasonic Backscatter Measurements of Musculoskeletal Properties

    This study aims to introduce the protocol for ultrasonic backscatter measurements of musculoskeletal properties based on a novel ultrasonic...

    Dongsheng Bi, Lingwei Shi, ... Dean Ta in Phenomics
    Article 27 September 2023
  17. Exploring long-term cancer survivors’ care experiences and unmet needs: protocol for a qualitative study

    Background

    The number of cancer survivors has increased in recent decades, and the majority of them suffer from sequelae of their disease and...

    Christian Speckemeier, K Maus, ... A Neumann in BMC Cancer
    Article Open access 01 July 2024
  18. An electrical stimulation intervention protocol to prevent disuse atrophy and muscle strength decline: an experimental study in rat

    Background

    Skeletal muscle is negatively impacted by conditions such as spaceflight or prolonged bed rest, resulting in a dramatic decline in muscle...

    Haiwang Shi, Fan Li, ... Rui Duan in Journal of NeuroEngineering and Rehabilitation
    Article Open access 29 June 2023
  19. Study protocol: fish oil supplement in prevention of oxaliplatin-induced peripheral neuropathy in adjuvant colorectal cancer patients – a randomized controlled trial. (OxaNeuro)

    Background

    Oxaliplatin-induced peripheral neuropathy (OIPN) in general and painful OIPN in particular is a debilitating late effect that severely...

    Nina Lykkegaard Gehr, Páll Karlsson, ... Lise Ventzel in BMC Cancer
    Article Open access 03 February 2024
  20. Preoperative chemoradiotherapy using tegafur/uracil, oral leucovorin, and irinotecan (TEGAFIRI) followed by oxaliplatin-based chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: the study protocol for a phase II trial

    Background

    Total neoadjuvant therapy (TNT) is a novel treatment strategy that is an alternative to preoperative chemoradiotherapy (CRT) for locally...

    Shinya Abe, Kazushige Kawai, ... Soichiro Ishihara in BMC Cancer
    Article Open access 17 May 2023
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