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Temporal and spatial variability of dynamic microstate brain network in early Parkinson’s disease
Changes of brain network dynamics reveal variations in macroscopic neural activity patterns in behavioral and cognitive aspects. Quantification and...
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Impact of distinct cognitive domains on gait variability in individuals with mild cognitive impairment and dementia
BackgroundGait variability is a common feature in neurodegenerative diseases and has been linked to cognitive impairment. Despite this link, the...
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Comparative epigenetic and genetic spatial structure in Mediterranean mountain plants: a multispecies study
Changes in epigenetic states can allow individuals to cope with environmental changes. If such changes are heritable, this may lead to epigenetic...
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Inter-individual, hemispheric and sex variability of brain activations during numerosity processing
Numerosity perception is a fundamental and innate cognitive function shared by both humans and many animal species. Previous research has primarily...
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Response sub-additivity and variability quenching in visual cortex
Sub-additivity and variability are ubiquitous response motifs in the primary visual cortex (V1). Response sub-additivity enables the construction of...
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Exploring shared neural substrates underlying cognition and gait variability in adults without dementia
BackgroundHigh gait variability is associated with neurodegeneration and cognitive impairments and is predictive of cognitive impairment and...
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Impact of stretch on sarcomere length variability in isolated fully relaxed rat cardiac myocytes
The contractility of cardiac muscle is greatly affected by preload via the Frank-Starling mechanism (FSM). It is based on preload-dependent...
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Temporal and spatial goal-directed reaching in upper limb prosthesis users
Understanding the fundamental characteristics of prosthetic movement control is imperative in improving prosthesis design and training. This study...
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New Insights into the Neuropsychological Profile and Intellectual Quotient Variability in Joubert Syndrome Compared to Other Congenital Cerebellar Malformations
The neuropsychological characteristics of the cerebellar cognitive affective syndrome (CCAS) in congenital, non-progressive malformations of the...
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Variability in Hemispheric Functional Segregation Phenotypes: A Review and General Mechanistic Model
Many functions of the human brain are organized asymmetrically and are subject to strong population biases. Some tasks, like speaking and making...
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Within-Individual BOLD Signal Variability and its Implications for Task-Based Cognition: A Systematic Review
Within-individual blood oxygen level-dependent (BOLD) signal variability, intrinsic moment-to-moment signal fluctuations within a single individual...
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Single-Cell and Spatial Analysis of Emergent Organoid Platforms
Organoids have emerged as a promising advancement of the two-dimensional (2D) culture systems to improve studies in organogenesis, drug discovery,... -
Combined spatial and frequency encoding for electrotactile feedback of myoelectric signals
Electrotactile stimulation has been commonly used in human–machine interfaces to provide feedback to the user, thereby closing the control loop and...
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Decoding the tumor microenvironment with spatial technologies
Visualization of the cellular heterogeneity and spatial architecture of the tumor microenvironment (TME) is becoming increasingly important to...
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Spatial transcriptomics in development and disease
The proper functioning of diverse biological systems depends on the spatial organization of their cells, a critical factor for biological processes...
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Spatial genomic, biochemical and cellular mechanisms underlying meningioma heterogeneity and evolution
Intratumor heterogeneity underlies cancer evolution and treatment resistance, but targetable mechanisms driving intratumor heterogeneity are poorly...
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Local signal variability and functional connectivity: Sensitive measures of the excitation-inhibition ratio?
A novel network version of permutation entropy, the inverted joint permutation entropy (JPE inv ), holds potential as non-invasive biomarker of...
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Auditory, tactile, and multimodal noise reduce balance variability
Auditory and somatosensory white noise can stabilize standing balance. However, the differential effects of auditory and tactile noise stimulation on...
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Heart Rate Variability Components in Electromagnetic Hypersensitive Persons
Electromagnetic radiation hypersensitivity (EHS) has been recognized as a rare chronic condition potentially associated with various serious... -
Functional individual variability development of the neonatal brain
Individual variability in cognition and behavior results from the differences in brain structure and function that have already emerged before birth....