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ClC-K Kidney Chloride Channels: From Structure to Pathology
The molecular basis of chloride transport varies all along the nephron depending on the tubular segments especially in the apical entry of the cell....
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Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium
Atopic dermatitis is a chronic inflammatory disorder with rising prevalence. The safety concerns over usually used steroids are driving the need for...
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Effect of Sodium Chloride, Sodium Nitrite and Sodium Nitrate on the Infectivity of Hepatitis E Virus
Hepatitis E virus (HEV) infection can cause acute and chronic hepatitis in humans. The zoonotic HEV genotype 3, which is highly prevalent in Europe,...
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Solution-Based Dosage Forms and Sterile Products
This chapter expands upon the concept of drug solubility and dissolution as it relates to dosage form design. Excipients utilized in solution-based...
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Efficacy of sodium bicarbonate ingestion strategies for protecting blinding
Sodium bicarbonate (NaHCO 3 ) is a widely researched ergogenic aid, but the optimal blinding strategy during randomised placebo-controlled trials is...
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The Development of Pathological Dependence after Intermittent Use of Sodium Glutamate, but Not Sucrose or Sodium Chloride Solutions
The possibility of development of dependence was studied during the intermittent consumption of sucrose, sodium chloride, and sodium glutamate...
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Light-Driven Sodium Pump as a Potential Tool for the Control of Seizures in Epilepsy
The marine flavobacterium Krokinobactereikastus light-driven sodium pump (KR2) generates an outward sodium ion current under 530 nm light...
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Evaluation of a wearable fabric-based sensor for accurate sodium determination in sweat during exercise
IntroductionNewly developed wearable fabric sensors (WFS) can increase the ease and accuracy of sweat sodium measurements by performing simultaneous...
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Lyotropic liquid crystalline nanoparticles for oral delivery: formulation and evaluation of sustained-released cromolyn sodium loaded cubosomes
PurposeCromolyn sodium, a so-called “mast cell stabilizer”, is well-known to prevent mast cells from triggering the immune response. However, the...
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The effects of sodium bicarbonate ingestion on swimming interval performance in trained competitive swimmers
The use of sodium bicarbonate (NaHCO 3 ) supplementation to improve repeated high-intensity performance is recommended; however, most swimming...
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Clues and new evidences in arterial hypertension: unmasking the role of the chloride anion
The present review will focus on the role of chloride anion in cardiovascular disease, with special emphasis in the development of hypertensive...
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Pharmacology of Compounds Targeting Cation–Chloride Cotransporter Physiology
Transporters of the solute carrier family 12 (SLC12) carry inorganic cations such as Na+ and/or K+ alongside Cl across the plasma membrane of cells....
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Physiological Functions of the Volume-Regulated Anion Channel VRAC/LRRC8 and the Proton-Activated Chloride Channel ASOR/TMEM206
Volume-regulated anion channels (VRACs) and the acid-sensitive outwardly rectifying anion channel (ASOR) mediate flux of chloride and small organic...
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The (in)dependency of blood and sweat sodium, chloride, potassium, ammonia, lactate and glucose concentrations during submaximal exercise
PurposeTo reduce the need for invasive and expensive measures of human biomarkers, sweat is becoming increasingly popular in use as an alternative to...
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Croscarmellose Sodium as Pelletization Aid in Extrusion-Spheronization
Only few excipients are known to be suitable as pelletization aids. In this study, the potential use of croscarmellose sodium (CCS) as pelletization...
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Mercury chloride alters heterochromatin domain organization and nucleolar activity in mouse liver
Mercury is a highly toxic element that induces severe alterations and a broad range of adverse effects on health. Its exposure is a global concern...
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Vitamin K2 protects against aluminium chloride-mediated neurodegeneration
Recent studies have shown that, coupled with other environmental factors, aluminium exposure may lead to neurodegeneration resulting in cognitive...
