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Adverse drug reactions associated with COVID-19 management
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) outbreak, which causes COVID-19, had a devastating impact on both...
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A highlight on carbamazepine-induced adverse drug reactions in Saudi Arabia: a retrospective medical records-based study
The link between human leukocyte antigen (HLA) alleles and carbamazepine-induced cutaneous, respiratory, and gastrointestinal adverse drug reactions...
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Influence of pharmacogenomic polymorphisms on allopurinol-induced cutaneous adverse drug reactions in Thai patients
BackgroundAllopurinol has been causing substantial morbidity and mortality particularly in Asian population by producing cutaneous adverse drug...
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The relationship between medication literacy and skin adverse reactions in non-small-cell lung cancer patients undergoing targeted EGFR-TKI therapy
BackgroundHigh medication literacy is the basis of rational medication application and is essential for the management of severe adverse drug...
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Avoidance of cutaneous adverse drug reactions induced by antiepileptic drugs based on pharmacogenomics
Pharmacogenomics (PGx) is a research area aimed at identifying genetic factors that are associated with drug responses, including drug efficacy,...
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Safety analysis of therapeutic drugs for breast cancer patients and construction of a predictive model for serious adverse drug reactions
ObjectivesTo explore the characteristics of the occurrence of antineoplastic drug adverse reactions (ADRs) in breast cancer and to utilize a...
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Adverse drug reactions of Rituximab in patients suffering from autoimmune neurological diseases
BackgroundRituximab, a chimeric human/mouse monoclonal antibody targeting CD-20 antigens, has been used recently for various rheumatological and...
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Pharmacovigilance of cutaneous adverse drug reactions in associations with drugs and medical conditions: a retrospective study of hospitalized patients
BackgroundCutaneous adverse drug reaction (CADR) is a common problem in clinical medication. This study aimed to investigate the correlation between...
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Cardiovascular Adverse Drug Reactions of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies for Migraine Prevention: An Analysis from the European Spontaneous Adverse Event Reporting System
IntroductionAnti-calcitonin gene-related peptide monoclonal antibodies (anti-CGRP-mAbs) have recently been approved for the prevention of migraine,...
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Drug Allergy and Cutaneous Adverse Reactions
Allergy or hypersensitivity to drugs often affects the skin and sometimes also mucosa. While immediate type reactions show a rather homogeneous...
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Development and application of Adverse drug reactions reports QUality Algorithm (AQUA-12) score: a single-centre quality improvement initiative
PurposeTo develop a reliable assessment tool to monitor the quality of adverse drug reaction (ADR) reports and evaluate its performance within a...
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Adverse drug reactions to chloroquine/hydroxychloroquine in combination with azithromycin in COVID-19 in-patients: data from intensive pharmacovigilance in Morocco, 2020
In Morocco, chloroquine/hydroxychloroquine + azithromycin have been used off-label for COVID-19 treatment. This study aimed to describe the...
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The Immunogenetics of Cutaneous Drug Reactions
Adverse drug reactions (ADRs) areAdverse drug reactions the cause of nearly three to six percent of inpatient admissions and are associated with high...
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Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
BackgroundThe management of uncontrolled severe asthma has greatly improved since the advent of novel biologic therapies. Up to August 2022, five...
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Efficacy of aluminum chloride in severe regorafenib-associated hand-foot skin reactions: a single-arm trial
BackgroundRegorafenib, a multikinase inhibitor, causes a high frequency of hand-foot skin reactions (HFSRs). The present study evaluated the efficacy...
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Chitosan-based drug delivery systems for skin atopic dermatitis: recent advancements and patent trends
Atopic dermatitis (AD) is a complex, relapsing inflammatory skin disease with a considerable social and economic burden globally. AD is primarily...
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Relationship of cytochrome P450 gene polymorphisms with blood concentrations of hydroxychloroquine and its metabolites and adverse drug reactions
BackgroundHydroxychloroquine (HCQ) is a cornerstone therapy for systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). This study aimed to...
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Analysis of differential gene immune infiltration and clinical characteristics of skin cutaneous melanoma based on systems biology and drug repositioning methods to identify drug candidates for skin cutaneous melanoma
Skin cutaneous melanoma (SKCM) has a low early detection rate and a high mortality rate. There are many problems such as side effects and drug...
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Macrolides in Chronic Skin Disorders
Macrolide antibiotics are widely used to treat infections of soft tissues and the respiratory tract due to their efficacy against Gram-negative and...
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Silymarin as a preventive or therapeutic measure for chemotherapy and radiotherapy-induced adverse reactions: a comprehensive review of preclinical and clinical data
PurposeThus far, silymarin has been examined in several studies for prevention or treatment of various chemotherapy or radiotherapy-induced adverse...
