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Axicabtagene ciloleucel as second-line therapy in large B cell lymphoma ineligible for autologous stem cell transplantation: a phase 2 trial
Axicabtagene ciloleucel (axi-cel) demonstrated superior efficacy compared to standard of care as second-line therapy in patients with high-risk...
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Continuously improving outcome over time after second allogeneic stem cell transplantation in relapsed acute myeloid leukemia: an EBMT registry analysis of 1540 patients
Second allogeneic stem cell transplantation (alloSCT2) is among the most effective treatments for acute myeloid leukemia (AML) relapse after first...
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HLA in Transplantation
This chapter is about kidney and bone marrow transplantation, a therapy that is routinely used in our hospitals to correct a failure of different...
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Immunology of Transplantation and Malignancy
Successful transplantation requires a multitude of important steps: surgical asepsis, development of surgical techniques of vascular anastomosis,...
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Monoclonal Antibodies in Solid Organ Transplantation
In an attempt to target solid organ transplant immunosuppression, monoclonal antibodies directed against key steps in specific immunologic pathways...
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Effect of Hematopoietic Stem Cell Transplantation and Post-Transplantation Cyclophosphamide on the Microglia Phenotype in Rats with Experimental Allergic Encephalomyelitis
Microglia are the resident immune cells of the central nervous system, playing a role in the inflammatory process development and resolution,...
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Carotid artery transplantation of brain endothelial cells enhances neuroprotection and neurorepair in ischaemic stroke rats
Brain microvascular endothelial cells (BMECs), an important component of the neurovascular unit, can promote angiogenesis and synaptic formation in...
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Liver transplantation in metastatic colorectal cancer: are we ready for it?
Colorectal cancer (CRC) is a prevalent disease worldwide, with more than 50% of patients develo** metastases to the liver. Five-year overall...
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Uncommon Transplantation Sites: Transplantation of Islets and Islet Organoids in the Anterior Chamber of the Eye of Rodents and Monkeys
The anterior chamber of the eye is a highly vascularized and innervated location that is also particularly rich in oxygen and immune privileged. This...
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An International Survey of Allogeneic Hematopoietic Cell Transplantation for X-Linked Agammaglobulinemia
PurposeX-linked agammaglobulinemia (XLA) is an inborn error of immunity caused by variants in Bruton’s tyrosine kinase ( BTK ). XLA patients require...
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Mitochondrial Transportation, Transplantation, and Subsequent Immune Response in Alzheimer’s Disease: An Update
Alzheimer’s disease (AD) is a devastating neurodegenerative disease characterized by memory impairment and a progressive decline in cognitive...
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Possible role of lncRNAs in amelioration of Parkinson’s disease symptoms by transplantation of dopaminergic cells
Long non-coding RNAs (lncRNAs) are biomarkers for diagnosis and treatment of Parkinson’s disease (PD). Since dopaminergic cell transplantation is a...
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Changes in tuberculosis risk after transplantation in the setting of decreased community tuberculosis incidence: a national population-based study, 2008–2020
BackgroundTransplant recipients are immunocompromised and vulnerable to develo** tuberculosis. However, active tuberculosis incidence is rapidly...
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Novel technique for arterial reconstruction in simultaneous pancreas-kidney transplantation, a randomized clinical trial
IntroductionSimultaneous pancreas kidney (SPK) transplantation is an invaluable procedure to enhance the quality of life of insulin-dependent...
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KiT-GENIE, the French genetic biobank of kidney transplantation
KiT-GENIE is a monocentric DNA biobank set up to consolidate the very rich and homogeneous DIVAT French cohort of kidney donors and recipients (D/R)...
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Neurologic Status of Patients with Purine Nucleoside Phosphorylase Deficiency Before and After Hematopoetic Stem Cell Transplantation
BackgroundPurine nucleoside phosphorylase (PNP) deficiency is a rare autosomal recessive combined immunodeficiency. The phenotype is profound T cell...
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Complement Inhibition in Kidney Transplantation: Where Are We Now?
Kidney transplantation is a life-saving strategy for patients with end-stage renal disease. Although progress has been made in the field of...
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Real-world data of long-term survival in patients with T-cell lymphoma who underwent stem cell transplantation
This study aimed to identify the benefits of autologous-stem cell transplantation (auto-SCT) and allogeneic-SCT (allo-SCT) in patients with...
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Transplantation of Wnt5a-modified Bone Marrow Mesenchymal Stem Cells Promotes Recovery After Spinal Cord Injury via the PI3K/AKT Pathway
Spinal cord injury (SCI) is a severe neurological condition that can lead to paralysis or even death. This study explored the potential benefits of...
