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Tuberculosis Vaccine: Past Experiences and Future Prospects
Vaccines are the best prophylactic measure that have eradicated several diseases like polio, measles, and small pox. Currently, efficient vaccines...
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Pulmonary non-tuberculous mycobacterial infections: current state and future management
Currently, there is a trend of increasing incidence in pulmonary non-tuberculous mycobacterial infections (PNTM) together with a decrease in...
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Non-small Cell Lung Cancer
Non-small cell lung cancer (NSCLC) is most common cause of cancer death in the world. Early detection, diagnosis and treatments are the essential...
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Cancer Immunotherapy: Friend or Foe of Mental Health?
Cancer morbidity with mental healthMental health problems is of utmost importance due to its considerable impact on mortality. Clinical trials...
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Immune Therapy
Lung cancer has long been considered an unsuitable target for immunotherapy due to its proposed immunoresistant properties. However, recent evidence...
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Lung Cancer: Diagnosis and Treatment Approach
Lung cancer is one of the most common causes of cancer death in the world. There are many risk factors for lung cancer including tobacco smoking,...
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Biological therapy of lung cancer
Bacillus Calmette Guerin (BCG) was the first biotherapy tested in lung cancer in the modern era. Early randomized trials suggested that various forms...
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Immunotherapeutical Potential of Mycobacterium Vaccae on M. Tuberculosis Infection in Mice
Tuberculosis remains the worldwide infectious disease. To identify the therapeutic potential of M. vaccae in treating tuberculosis, M. vaccae was...
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The hygiene hypothesis and affective and anxiety disorders
Chronic inflammatory disorders are increasing in prevalence in the developed countries. The hygiene hypothesis proposes that our changing microbial...
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Prostate Cancer Vaccines
Standard systemic treatment of prostate cancer today is comprised of antihormonal and cytostatic agents. Vaccine therapy of prostate cancer is...
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Clinical and immunological assessment of Mycobacterium vaccae (SRL172) with chemotherapy in patients with malignant mesothelioma
The objectives of this study were to determine the toxicity of intratumoural/intrapleural SRL172 in addition to intradermal SRL172 and standard...
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A randomized phase II study of SRL172 (Mycobacterium vaccae) combined with chemotherapy in patients with advanced inoperable non-small-cell lung cancer and mesothelioma
Mycobacterial preparations have been used with limited success against cancer apart from superficial bladder cancer. Recently, a therapeutic vaccine...
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The immunotherapy of prostate cancer
Advanced prostate cancer remains incurable with standard treatment options. Immunotherapy may be a realistic alternative given the growing evidence...
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Prospects for the Development of New Vaccine Adjuvants
This review focuses on the impact of various new adjuvant formulations on the efficacy of existing and new human vaccines.
Despite major advances in...