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Translating Cadaveric Injury Risk to Dummy Injury Risk at Iso-energy
Injury risk assessment based on cadaver data is essential for informing safety standards. The common ‘matched-pair’ method matches energy-based...
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Multi-risk factors joint prediction model for risk prediction of retinopathy of prematurity
PurposeRetinopathy of prematurity (ROP) is a retinal vascular proliferative disease common in low birth weight and premature infants and is one of...
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Prediction of esophageal cancer risk based on genetic variants and environmental risk factors in Chinese population
BackgroundResults regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are...
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Gene expression signature predicts radiation sensitivity in cell lines using the integral of dose–response curve
BackgroundAlthough substantial efforts have been made to build molecular biomarkers to predict radiation sensitivity, the ability to accurately...
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Novel Cell Quantification Method Using a Single Surrogate Calibration Curve Across Various Biological Samples
Quantitative polymerase chain reaction (qPCR) is generally used to quantify transplanted cell therapy products in biological samples. As the matrix...
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Risk Assessment and Risk-Benefit Assessment
The framework of risk analysis has become the principal procedure for dealing with food safety issues. Risk analysis consists of three components:...
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Fetal heart rate spectral analysis in raw signals and PRSA-derived curve: normal and pathological fetuses discrimination
AbstractCardiotocography (CTG) is the most common technique for electronic fetal monitoring and consists of the simultaneous recording of fetal heart...
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Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease
BackgroundThe presence of coronary plaques with high-risk characteristics is strongly associated with adverse cardiac events beyond the...
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Comparison of senhance and da vinci robotic radical prostatectomy: short-term outcomes, learning curve, and cost analysis
BackgroundThe Senhance® Robotic System is a new laparoscopy-based platform that has been increasingly used in radical prostatectomy (RP) procedures....
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Clinical Application of Polygenic Risk Score in IgA Nephropathy
Genome-wide association studies (GWASs) have identified 30 independent genetic variants associated with IgA nephropathy (IgAN). A genetic risk score...
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Relationship between self-reported sleep and cognitive function: a specification curve analysis
The relationship between self-reported sleep and cognitive function is complex; it is unclear whether self-reported sleep is a robust correlate of...
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Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
Bipolar disorder is a highly heritable and functionally impairing disease. The recognition and intervention of BD especially that characterized by...
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Development and validation of a prognostic model for assessing long COVID risk following Omicron wave—a large population-based cohort study
BackgroundLong coronavirus disease (COVID) after COVID-19 infection is continuously threatening the health of people all over the world. Early...
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Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women
BackgroundPrevious work in European ancestry populations has shown that adding a polygenic risk score (PRS) to breast cancer risk prediction models...
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Area under the curve of tacrolimus using microsampling devices: towards precision medicine in solid organ transplantation?
PurposeTherapeutic drug monitoring of tacrolimus using trough concentration (C min ) is mandatory to ensure drug efficacy and safety in solid organ...
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Seven-Single Nucleotide Polymorphism Polygenic Risk Score for Breast Cancer Risk Prediction in a Vietnamese Population
AbstractMultiple common variations discovered via genome-wide association studies (GWASs) were shown to have a minimal association with breast cancer...
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Construction of a Prognostic Risk Prediction Model Based on m6A-Associated Long Non-Coding RNAs in Cholangiocarcinoma
AbstractTo screen long non-coding RNAs (lncRNAs) associated with the N6-methyladenosine (m6A) gene and create a prognostic risk model for...
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On the use of receiver operating characteristic curve analysis to determine the most appropriate p value significance threshold
Backgroundp value is the most common statistic reported in scientific research articles. Choosing the conventional threshold of 0.05 commonly used...
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The Association Between Branched-Chain Amino Acid Concentrations and the Risk of Autism Spectrum Disorder in Preschool-Aged Children
Several studies have linked branched-chain amino acid (BCAA) metabolism disorders with autism spectrum disorder (ASD), but the results have been...
