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Mechanical power normalized to aerated lung predicts noninvasive ventilation failure and death and contributes to the benefits of proning in COVID-19 hypoxemic respiratory failure
BackgroundConcern exists that noninvasive ventilation (NIV) may promote ventilation-induced lung injury(VILI) and worsen outcome in acute hypoxemic...
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Robust airway microbiome signatures in acute respiratory failure and hospital-acquired pneumonia
Respiratory microbial dysbiosis is associated with acute respiratory distress syndrome (ARDS) and hospital-acquired pneumonia (HAP) in critically ill...
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Respiratory Syncytial Virus
Every year, millions of people are infected by the respiratory syncytial virus (RSV). Respiratory syncytial virus widely infects children as well as...
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HLA-B*07:02 and HLA-C*07:02 are associated with trimethoprim-sulfamethoxazole respiratory failure
We have identified an underrecognized severe adverse drug reaction (ADR) of trimethoprim-sulfamethoxazole (TMP-SMX) associated respiratory failure in...
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Predicting respiratory failure in patients infected by SARS-CoV-2 by admission sex-specific biomarkers
BackgroundSeveral biomarkers have been identified to predict the outcome of COVID-19 severity, but few data are available regarding sex differences...
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Synergistic Welfare of Synbiotic Nutraceuticals on Chronic Respiratory Diseases
The chapter titled “Synergistic Welfare of Synbiotic Nutraceuticals on Chronic Respiratory Diseases” explores the promising intersection of...
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Medicinal Mushrooms for Respiratory Health
Chronic respiratory disorders (CRDs) have been a key threat globally to the public health system. An estimated 545 million cases worldwide could...
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Relationship between perceived and neuromuscular fatigue in COPD patients with chronic respiratory failure with long-term oxygen therapy: a cross-sectional study
PurposeTo evaluate perceived fatigue (PF) and neuromuscular fatigue (NMF) in patients with COPD and chronic respiratory failure (CRF) on long-term...
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Description of pathogenic bacteria in patients with respiratory symptoms associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Colombia
Viral respiratory infections may predispose to co-infections with other pathogenic microorganisms. In this study, pathogenic respiratory bacteria...
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Stochastic Modelling of Respiratory System Elastance for Mechanically Ventilated Respiratory Failure Patients
While lung protective mechanical ventilation (MV) guidelines have been developed to avoid ventilator-induced lung injury (VILI), a one-size-fits-all ...
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Aquaporins in Respiratory System
Aquaporins (AQPs) are water channel proteins facilitating fluid transport in alveolar space, airway humidification, pleural fluid absorption, and...
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The relationship between use of SGLT2is and incidence of respiratory and infectious diseases and site-specific fractures: a meta-analysis based on 32 large RCTs
ObjectivesWe aimed to evaluate the relationship between use of sodium-glucose cotransporter-2 inhibitors (SGLT2is) and incidence of various...
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An implantable soft robotic ventilator augments inspiration in a pig model of respiratory insufficiency
Severe diaphragm dysfunction can lead to respiratory failure and to the need for permanent mechanical ventilation. Yet permanent tethering to a...
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A novel synonymous ABCA3 variant identified in a Chinese family with lethal neonatal respiratory failure
BackgroundLethal respiratory failure is primarily caused by a deficiency of pulmonary surfactant, and is the main cause of neonatal death among...
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Heat shock protein 27 in the pathogenesis of COVID-19 and non-COVID acute respiratory distress syndrome
Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure in intensive care units that has increased dramatically...
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Expanding the range of the respiratory infectome in Australian feedlot cattle with and without respiratory disease using metatranscriptomics
BackgroundBovine respiratory disease (BRD) is one of the most common diseases in intensively managed cattle, often resulting in high morbidity and...
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Peritoneal sepsis caused by Escherichia coli triggers brainstem inflammation and alters the function of sympatho-respiratory control circuits
BackgroundSepsis has a high mortality rate due to multiple organ failure. However, the influence of peripheral inflammation on brainstem autonomic...
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Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
BackgroundPatients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor...
