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Position of Biphenyl Group Turning the Structure and Photophysical Property of D-π- π -A Prototype Fluorescent Material
Three novel D-π-π-A prototype compounds, namely, (E)-2-(3-([1,1'-biphenyl]-2-yl)-1-(9H-fluoren-2-yl)allylidene)malononitri-le (2-BAM),...
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Characterization of Prototype Gummy Formulations Provides Insight into Setting Quality Standards
Gummy formulations are considered suitable alternatives to traditional oral dosage forms like tablets and capsules due to their merits that include...
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Antiviral role of IFITM3 in prototype foamy virus infection
BackgroundFoamy viruses (FVs) are retroviruses with unique replication strategies that cause lifelong latent infections in their hosts. FVs can also...
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Instance-based learning with prototype reduction for real-time proportional myocontrol: a randomized user study demonstrating accuracy-preserving data reduction for prosthetic embedded systems
AbstractThis work presents the design, implementation and validation of learning techniques based on the kNN scheme for gesture detection in...
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Immunoglobulin and T cell receptor repertoire changes induced by a prototype vaccine against Chagas disease in naïve rhesus macaques
BackgroundA vaccine against Trypanosoma cruzi , the agent of Chagas disease, would be an excellent additional tool for disease control. A recombinant...
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A Prototype of a Myoelectric Upper-Limb Prosthesis Constructed Using Additive Technologies
A low-cost bionic hand prosthesis with myoelectric control is presented. The prosthesis was made from plastic by 3D printing. An algorithm for...
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Single-crystal Drying: Development of a Continuous Drying Prototype to Optimize Particle Flow and Residence Time Distribution
PurposeIn the pharmaceutical industry, there has been a growing interest in continuous manufacturing in recent years. Many efforts have been made to...
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Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas
BackgroundPrototype foamy virus (PFV) is nonpathogenic complex retroviruses that express a transcriptional transactivator Tas, which is essential for...
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Accuracy of a Low-Cost Continuous Subcutaneous Insulin Infusion Pump Prototype: In Vitro Study Using Combined Methodologies
Considering that infusion devices are safety-critical systems, the main goal of this paper is to evaluate the infusion accuracy and precision of a...
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Proof-of-concept and concurrent validity of a prototype headset to assess peak oxygen uptake without a face mask
ObjectivePortable gas exchange instruments allow the assessment of peak oxygen uptake (V̇O 2peak ) but are often bulky, expensive and require wearing...
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Jackdaws form categorical prototypes based on experience with category exemplars
Categorization represents one cognitive ability fundamental to animal behavior. Grou** of elements based on perceptual or semantic features helps...
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A modified live bat influenza A virus-based vaccine prototype provides full protection against HPAIV H5N1
Highly pathogenic avian influenza viruses (HPAIVs) of subtype H5 are a major threat for poultry holdings worldwide, here especially the zoonotic...
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Testing and evaluation of lower limb prosthesis prototypes in people with a transfemoral amputation: a sco** review on research protocols
BackgroundWhen develo** new lower limb prostheses, prototypes are tested to obtain insights into the performance. However, large variations between...
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Comparison of bivalent and monovalent SARS-CoV-2 variant vaccines: the phase 2 randomized open-label COVAIL trial
Vaccine protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection wanes over time, requiring updated boosters. In a...
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Steering-by-leaning facilitates intuitive movement control and improved efficiency in manual wheelchairs
BackgroundManual wheelchair propulsion is widely accepted to be biomechanically inefficient, with a high prevalence of shoulder pain and injuries...
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Vibration motor stimulation device in smart leggings that promotes motor performance in older people
Globally, accelerated aging is taking place alongside increased life expectancy of the population. This poses a challenge to maintaining autonomy and...
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Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation
BackgroundMeasurements of the amyloid-β (Aβ) 42/40 ratio in blood plasma may support the early diagnosis of Alzheimer’s disease and aid in the...
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Piezoelectric Transformer-Based High-Voltage Pulse Generator Using Wide-Bandgap Semiconductors for Medical Electroporation Therapy
In this paper, a new application of Piezoelectric Transformer (PT)-based power converters to generate high-voltage (HV) bipolar pulses for medical...
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Rapid detection of SARS-CoV-2 RNA in saliva via Cas13
Rapid nucleic acid testing is central to infectious disease surveillance. Here, we report an assay for rapid COVID-19 testing and its implementation...
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Blood and cerebrospinal fluid flow oscillations measured with real-time phase-contrast MRI: breathing mode matters
BackgroundCervical blood and cerebrospinal fluid (CSF) flow rates can be quantified with Phase-contrast (PC) MRI, which is routinely used for...
