Search
Search Results
-
Rehmannia glutinosa polysaccharides: a review on structure-activity relationship and biological activity
Rehmannia glutinosa has been used historically and is now listed in the 2020 Chinese Pharmacopoeia as a traditional Chinese medicine for nourishing...
-
Study on morphological and genetic diversity of Rehmannia glutinosa cultivated in Japan
It is said that Rehmannia glutinosa is grouped into two types, Akaya and Kaikei, in Japan. However, previous reports of genetic analysis of R....
-
Catalpol Mitigates Alzheimer's Disease Progression by Promoting the Expression of Neural Stem Cell Exosomes Released miR-138-5p
Alzheimer’s disease (Alzheimer’s disease, AD) is a neurodegenerative disease characterized by senile plaque deposition and neurofibrillary tangles....
-
Catalpol Alleviates Ischemic Stroke Through Promoting Angiogenesis and Facilitating Proliferation and Differentiation of Neural Stem Cells via the VEGF-A/KDR Pathway
Stroke is one of the leading causes of disability and death globally with a lack of effective therapeutic strategies. Catalpol is a bioactive...
-
Identification of rehmannia virus 1, a novel putative member of the genus Closterovirus, from Rehmannia glutinosa
Transcriptome sequencing analysis of a symptomatic Rehmannia glutinosa plant revealed a virome containing two known RNA viruses and one novel virus....
-
Catalpol Ameliorates Oxidative Stress and Neuroinflammation after Traumatic Brain Injury in Rats
Oxidative stress and neuroinflammation are deemed the prime causes of neurological damage after traumatic brain injury (TBI). Catalpol, an active...
-
The protective effects of Nin**’yoeito against liver steatosis/fibrosis in a non-alcoholic steatohepatitis model mouse
Non-alcoholic steatohepatitis (NASH) is a progressive fibrotic form of non-alcoholic fatty liver disease. Liver fibrosis leads to liver cancer and...
-
Catalpol improves impaired neurovascular unit in ischemic stroke rats via enhancing VEGF-PI3K/AKT and VEGF-MEK1/2/ERK1/2 signaling
Neurovascular unit (NVU) is organized multi-cellular and multi-component networks that are essential for brain health and brain homeostasis...
-
Anti-coronavirus and anti-pulmonary inflammation effects of iridoids, the common component from Chinese herbal medicines for the treatment of COVID-19
The practice of Chinese herbal medicines for the treatment of COVID-19 in China played an essential role for the control of mortality rate and...
-
-
Complete genome sequence of a novel closterovirus isolated from Dregea volubilis
The complete genome sequence of a putative novel closterovirus, tentatively named "Dregea volubilis closterovirus 1" (DvCV1, GenBank accession no....
-
Combined Catalpol and Tetramethylpyrazine Promote Axonal Plasticity in Alzheimer’s Disease by Inducing Astrocytes to Secrete Exosomes Carrying CDK5 mRNA and Regulating STAT3 Phosphorylation
Alzheimer’s disease (AD) is a common progressive degenerative disease of the central nervous system in aging populations. This study aimed to...
-
Drug-interaction between paclitaxel and gosha**kigan extract and its constituents
Paclitaxel, a standard chemotherapeutic agent for several types of cancer, including ovarian, breast, and non-small-cell lung cancer, causes...
-
Probing of plant transcriptomes reveals the hidden genetic diversity of the family Secoviridae
Secoviruses are single-stranded RNA viruses that infect plants. In the present study, we identified 61 putative novel secoviral genomes in various...
-
A study on the mechanism of Beclin-1 m6A modification mediated by catalpol in protection against neuronal injury and autophagy following cerebral ischemia
ObjectiveCatalpol (CAT) has various pharmacological activities and plays a protective role in cerebral ischemia. It has been reported that CAT played...
-
Oral administration of Rehmannia glutinosa extract for obesity treatment via adiposity and fatty acid binding protein expression in obese rats
We investigated the anti-obesity effect of Rehmannia glutinosa aqueous extract (RGE) in high fat diet (HFD) induced obese rats on the blood lipid...
-
Isolation and molecular characterization of a tomato brown rugose fruit virus mutant breaking the tobamovirus resistance found in wild Solanum species
A new tobamovirus named tomato brown rugose fruit virus (ToBRFV) overcomes the effect of the Tm-1 , Tm-2 , and Tm-2 2 resistance genes introgressed from...
-
-
Research progress on the mechanism of traditional Chinese medicine regulating intestinal microbiota to combat influenza a virus infection
Influenza A viruses (IAV) are a prevalent respiratory pathogen that can cause seasonal flu and global pandemics, posing a significant global public...
-
Alternative Therapies for Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect caused by many antineoplastic drugs. Currently, there are no FDA-approved...