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Structure–Function of TMEM16 Ion Channels and Lipid Scramblases
The TMEM16 protein family comprises two novel classes of structurally conserved but functionally distinct membrane transporters that function as...
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Proprioceptive thalamus receiving forelimb and neck muscle spindle inputs via the external cuneate nucleus in the rat
Proprioceptive signals from body muscles have historically been considered to project to the rostrodorsal shell of the ventrobasal thalamic complex...
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Function and Regulation of the Calcium-Activated Chloride Channel Anoctamin 1 (TMEM16A)
Various human tissues express the calcium-activated chloride channel Anoctamin 1 (ANO1), also known as TMEM16A. ANO1 allows the passive chloride flux...
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A comparative study of human betacoronavirus spike proteins: structure, function and therapeutics
Coronaviruses are the paradigm of emerging 21 st century zoonotic viruses, triggering numerous outbreaks and a severe global health crisis. The...
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Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China
ObjectiveThis study summarizes and compares clinical and laboratory characteristics of 34 patients admitted to the intensive care unit (ICU) for...
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Possible aerosol transmission of COVID-19 and special precautions in dentistry
Since its emergence in December 2019, corona virus disease 2019 (COVID-19) has impacted several countries, affecting more than 90 thousand patients...
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Weathering the storm: COVID-19 infection in patients with hematological malignancies
The Coronavirus disease 2019 (COVID-19) is an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)....
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An overview of COVID-19
Pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection emerged in Wuhan City, Hubei Province, China in December...
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Angiotensin II-derived reactive oxygen species underpinning the processing of the cardiovascular reflexes in the medulla oblongata
The brainstem is a major site in the central nervous system involved in the processing of the cardiovascular reflexes such as the baroreflex and the...
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Inhibitory activities of microalgal extracts against Epstein-Barr virus DNA release from lymphoblastoid cells
This study aimed to assess the inhibitory activities of methanol extracts from the microalgae Ankistrodesmus convolutus , Synechococcus elongatus , and S...
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Wolbachia modification of sperm does not always require residence within develo** sperm
Wolbachia are maternally inherited intracellular bacteria known to manipulate the reproduction of their arthropod hosts. Wolbachia commonly affect...
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Deep brain stimulation in Tourette’s syndrome
Tourette’s Syndrome (TS) is a neuropsychiatric disorder characterized by motor and vocal tics, often associated with behavioral disorders. Symptoms...
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Strategy for AIDS prevention and treatment
HIV/AIDS has been circulating in China for over 25 year. While making progress and achievements on HIV/AIDS prevention, there still are great...
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Integrin activation and viral infection
Integrins are members of a ubiquitous membrane receptor family which includes 18 different α subunits and 8 β subunits forming more than 20 α/β...
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AIDS research and its role in China’s AIDS prevention and control policies
By the end of 2005, the estimated number of HIV infected people in China was 650,000. The seriousness of the epidemic calls for effective control...
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A general introduction of HIV/AIDS treatment with Traditional Chinese Medicine in China
This paper gives a general introduction of HIV/AIDS treatment with Traditional Chinese Medicine (TCM) in China during the past 20 years. Although the...
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Establishment of AIDS animal model with SIVmac239 infected Chinese rhesus monkey
In the present research, two Chinese rhesus monkeys were inoculated intravenously with 5000 TCID 50 of SIVmac239. The changes in the numbers of CD4 + T...
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HIV vaccine-challenges and opportunities
The need for an efficacious HIV/AIDS vaccine remains the highest priority of the world HIV/AIDS agenda. The generation of an efficacious HIV/AIDS...
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Frequency and absolute number of FoxP3+ regulatory T cells correlate with disease progression of chronic HIV-1 infection
CD4 + CD25 + Regulatory T cells (Treg) have been found to down-regulate immune activation in HIV-1 infection. However, whether the depletion of Treg...