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Regulatory Effects and Mechanisms of L-Theanine on Neurotransmitters via Liver–Brain Axis Under a High Protein Diet
Excessive protein intake causes liver and brain damage and neurotransmitter disorders, thereby inducing cognitive dysfunction. L-theanine can...
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Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression
AbstractChitinase-3-like 1 protein (CHI3L1) is a secreted glycoprotein, strongly correlated with fibrosis severity in chronic liver diseases...
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Ketogenic Diet and Drug-Resistant Epilepsy
The ketogenic diet is a high-fat, low-carbohydrate, and restricted protein diet that is used in children with drug-resistant epilepsy. Over the past...
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Influence of Ketogenic Diet on Diabetes
The effectiveness of limiting the intake of carbohydrates in obese individuals and people with diabetes is still subject to debate, even though...
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Underrated aspects of a true Mediterranean diet: understanding traditional features for worldwide application of a “Planeterranean” diet
Over the last decades, the Mediterranean diet gained enormous scientific, social, and commercial attention due to proven positive effects on health...
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Ketogenic Diet and Inflammation : Implications for Mood and Anxiety Disorders
The ketogenic diet, known as a low-carbohydrate, high-protein, and high-fat diet, drastically restrains the major source of energy for the body,...
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Differential bone metabolism and protein expression in mice fed a high-fat diet versus Daurian ground squirrels following natural pre-hibernation fattening
This study compared the effects on bone metabolism and morphology of pathological obesity induced by excessive fat intake in a non-hibernator (mice)...
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Ceftriaxone reverses diet-induced deficits in goal-directed control
RationaleObesity is associated with numerous health risks and ever-increasing rates are a significant global concern. However, despite weight loss...
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Very-low-calorie ketogenic diet vs hypocaloric balanced diet in the prevention of high-frequency episodic migraine: the EMIKETO randomized, controlled trial
BackgroundMigraine is the second world’s cause of disability. Among non-pharmacological treatments, nutritional intervention, particularly ketogenic...
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Calculating Diet-Induced Thermogenesis in Mice
Diet-induced thermogenesis (DIT) is the increase in energy expenditure (EE) associated with food intake. Increasing DIT may lead to weight loss, so...
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Effect of Diet Patterns in the Prevention of Alzheimer’s Disease
There are over 55 million people living with dementia worldwide. Alzheimer’s disease (AD) is the most common type of dementia and likely comprises up...
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Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium
BackgroundThe continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential...
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Deficiency of exchange protein directly activated by cAMP (EPAC)-1 in mice augments glucose intolerance, inflammation, and gut dysbiosis associated with Western diet
BackgroundGut microbiota (GM) dysregulation, known as dysbiosis, has been proposed as a crucial driver of obesity associated with “Western” diet (WD)...
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Effect of a Ketogenic Diet on Oxidative Posttranslational Protein Modifications and Brain Homogenate Denaturation in the Kindling Model of Epilepsy in Mice
This study focused on the ketogenic diet (KD) effects on oxidative posttranslational protein modification (PPM) as presumptive factors implicated in...
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Quercetin improved hepatic circadian rhythm dysfunction in middle-aged mice fed with vitamin D-deficient diet
We aimed to determine whether quercetin is capable of improving circadian rhythm and metabolism disorder under vitamin D-deficient condition....
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Can the ketogenic diet improve our dreams? Effect of very low-calorie ketogenic diet (VLCKD) on sleep quality
BackgroundObesity is a condition that is often associated with sleep disorders, including reduced sleep quality (SQ). Very low calorie ketogenic diet...
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Short-chain fatty acids: linking diet, the microbiome and immunity
The short-chain fatty acids (SCFAs) butyrate, propionate and acetate are microbial metabolites and their availability in the gut and other organs is...
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High salt diet induces cognitive impairment and is linked to the activation of IGF1R/mTOR/p70S6K signaling
A high-salt diet (HSD) has been associated with various health issues, including hypertension and cardiovascular diseases. However, recent studies...
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Ginkgolide C attenuated Western diet-induced non-alcoholic fatty liver disease via increasing AMPK activation
BackgroundNon-alcoholic steatohepatitis (NASH) is a metabolic dysregulation-related disorder that is generally characterized by lipid metabolism...
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Effect of omega-3 fatty acid diet on prostate cancer progression and cholesterol efflux in tumor-associated macrophages—dependence on GPR120
BackgroundPreclinical and clinical translational research supports the role of an ω-3 fatty acid diet for prostate cancer prevention and treatment....
