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Pro-resolving and anti-inflammatory effects of resolvins and protectins in rheumatoid arthritis
Rheumatoid arthritis (RA) is typified by persistent joint inflammation, which leads to the deterioration of bone and cartilage and a reduction in...
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The Ratio of Omega-6/Omega-3 Fatty Acid: Implications and Application as a Marker to Diabetes
Omega-3 and omega-6 groups of polyunsaturated fatty acids (PUFA) are non-interconvertible and metabolically and functionally different, with key...
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Resolution medicine in cancer, infection, pain and inflammation: are we on track to address the next Pandemic?
Uncontrolled inflammation giving rise to excessive tissue inflammation can lead to chronic inflammation that enhances tissue destruction, amplifying...
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The Ratio of Omega-6/Omega-3 Fatty Acid: Implications and Application as a Marker to Diabetes
Omega-3 and omega-6 groups of polyunsaturated fatty acids (PUFA) are non-interconvertible and metabolically and functionally different, with key...
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Neuroimmune Interactions in Pain Mechanisms and Therapeutics
As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be...
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Inflammation Resolution Mediators: Future Prospects
Inflammation resolution is a complex system that involves a variety of lipid mediators, proteins, hormones, and gaseous mediators that act in a...
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COVID-19 and cancer: start the resolution!
Coronavirus disease 2019 (COVID-19) due to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been an ongoing pandemic...
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Population snapshot of the extended-spectrum β-lactamase-producing Escherichia coli invasive strains isolated from a Hungarian hospital
BackgroundThis study was carried out to determine the prevalence and the genetic background of extended-spectrum β-lactamase-producing Escherichia...
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Mechanistic Understanding of Inflammation Resolution Using the Atlas of Inflammation Resolution (AIR)
The Atlas of Inflammation Resolution (AIR) is a comprehensive web-based resource that provides a platform for studying inflammation and inflammation...
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Polyunsaturated Fatty Acid-Derived Lipid Mediators as Biomarkers in Critical Care
Inflammation is a necessary and beneficial process that protects against injury and infection. However, dysregulated and unrestrained inflammation...
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Analysis of the Involvement of Susceptibility Genes to Coronary Heart Disease in Implementation Signaling and Metabolic Pathways
AbstractCoronary heart disease (CHD) is a common pathology, and its development is mediated by a large number of genetic factors, environmental...
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Anti-inflammatory signaling through G protein-coupled receptors
G protein-coupled receptors (GPCRs) play important roles in human physiology. GPCRs are involved in immunoregulation including regulation of the...
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Circulating Polyunsaturated Fatty Acids (PUFAs) as Biological Indicators in Trauma
Dietary polyunsaturated fatty acids (PUFAs) play a vital role in cell growth, development, and function, especially in maternal and early child...
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Exercise and Diet in the Control of Inflammation and Pain
Lifestyle choices, such as exercise and diet, can play significant roles in mediating inflammation and consequently, pain. Functional medicine is an...
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Limitation and Termination of the Immune Response: Influences of Food Components on the Downregulation and Termination of the Immunological Defense Response
Immune reactions must occur in a spatially and temporally limited manner within the framework of physiological homeostasis. Specific functional food...
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Polyunsaturated Fatty Acid-Derived Lipid Mediators as Biomarkers in Critical Care
Inflammation is a necessary and beneficial process that protects against injury and infection. However, dysregulated and unrestrained inflammation...
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Impacts of Omega-3 Fatty Acids, Natural Elixirs for Neuronal Health, on Brain Development and Functions
Omega-3 fatty acids play a seminal role in maintaining the structural and functional integrity of the nervous system. These specialized molecules...
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Vagus nerve stimulation and inflammation: expanding the scope beyond cytokines
Approximately 20 years ago it was discovered that the vagus nerve regulates pro-inflammatory cytokine levels and inflammation. Subsequent research...
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Are Multi-Component Drugs Better in Resolving the Inflammation Compared to the Single-Component Drugs?
As the cost of develo** novel single-component drugs is always increasing, multi-component drugs could be seen as a solution. Diseases often affect...
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Circulating Polyunsaturated Fatty Acids (PUFAs) as Biological Indicators in Trauma
Dietary polyunsaturated fatty acids (PUFAs) play a vital role in cell growth, development, and function, especially in maternal and early child...