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Clinical characteristics and long-term neurodevelopmental outcomes of leukomalacia in preterm infants and term infants: a cohort study
BackgroundLeukomalacia is a serious form of neonatal brain injury that often leads to neurodevelopmental impairment, and studies on neonatal...
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Increased PLAGL1 Gene Methylation in Cord Blood is Positively Correlated with Brain Injury in Chorioamniotic Preterm Infants
The study aims to explore the epigenetic mechanisms of neurodevelopmental impairment accompanied in chorioamniotic preterm infants. Our study...
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The role of time interval elimination on pain control of preterm infants by sucrose administration
PurposeThe 2-min time interval of sucrose administration given before minor painful procedures in preterm infants is based on a few limited studies....
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Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation
BackgroundProbiotic use in preterm infants can mitigate the impact of antibiotic exposure and reduce rates of certain illnesses; however, the benefit...
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Immunization of preterm infants: current evidence and future strategies to individualized approaches
Preterm infants are at particularly high risk for infectious diseases. As this vulnerability extends beyond the neonatal period into childhood and...
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Extremely Preterm Infants with a Near-total Absence of Cerebellum: Usefulness of Quantitative Magnetic Resonance in Predicting the Motor Outcome
This study aims to evaluate in extremely premature infants the severity of brain structural injury causing total absence or near-total absence of...
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The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe
BackgroundResearch indicates that preterm infants requiring prolonged mechanical ventilation often exhibit suboptimal neurodevelopment at follow-up,...
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TwinEDA: a sustainable deep-learning approach for limb-position estimation in preterm infants’ depth images
Early diagnosis of neurodevelopmental impairments in preterm infants is currently based on the visual analysis of newborns’ motion patterns by...
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Transcriptomic analysis delineates preterm prelabor rupture of membranes from preterm labor in preterm fetal membranes
BackgroundGlobally, preterm birth remains the leading cause of death in children younger than 5 years old. Spontaneous preterm birth is comprised of...
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Preterm Birth Alters the Regional Development and Structural Covariance of Cerebellum at Term-Equivalent Age
Preterm birth is associated with increased risk for a spectrum of neurodevelopmental disabilities. The cerebellum is implicated in a wide range of...
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Impact of early antibiotic exposure on the risk of colonization with potential pathogens in very preterm infants: a retrospective cohort analysis
BackgroundSepsis is one of the most important complications in preterm infants. For this reason, most preterm infants receive antibiotics during...
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Reading abilities in preterm children: a systematic review and meta-analysis
It is well recognized that children born preterm have specific learning difficulties. The objective of this study is to carry out a systematic review...
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Potential Role of Endoplasmic Reticulum Stress in Modulating Protein Homeostasis in Oligodendrocytes to Improve White Matter Injury in Preterm Infants
Preterm white matter injury (WMI) is a demyelinating disease with high incidence and mortality in premature infants. Oligodendrocyte cells (OLs) are...
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Chorioamnionitis accelerates granule cell and oligodendrocyte maturation in the cerebellum of preterm nonhuman primates
BackgroundPreterm birth is often associated with chorioamnionitis and leads to increased risk of neurodevelopmental disorders, such as autism....
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Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD program
BackgroundBronchopulmonary dysplasia (BPD) is a lung disease in premature infants caused by therapeutic oxygen supplemental and characterized by...
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Prediction of glomerular filtration rate maturation across preterm and term neonates and young infants using inulin as marker
Describing glomerular filtration rate (GFR) maturation across the heterogeneous population of preterm and term neonates and infants is important to...
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Prenatal risk factors and neonatal DNA methylation in very preterm infants
BackgroundPrenatal risk factors are related to poor health and developmental outcomes for infants, potentially via epigenetic mechanisms. We tested...
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Inoculation of mother’s own milk could personalize pasteurized donor human milk used for feeding preterm infants
BackgroundHuman milk is a vehicle for bioactive compounds and beneficial bacteria which promote the establishment of a healthy gut microbiome of...
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Administration of zinc to preterm infants with hypozincemia does not reduce serum copper concentrations in most cases: a single-center retrospective observational study
BackgroundZinc is an essential trace element involved in various physiological functions. In Japan, zinc acetate dihydrate is administered to...
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Longstanding Auditory Sensory and Semantic Differences in Preterm Born Children
More than 10% of births are preterm, and the long-term consequences on sensory and semantic processing of non-linguistic information remain poorly...
