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Corticospinal tract: a new hope for the treatment of post-stroke spasticity
Stroke is the third leading cause of death and disability worldwide. Post-stroke spasticity (PSS) is the most common complication of stroke but...
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Testing spasticity mechanisms in chronic stroke before and after intervention with contralesional motor cortex 1 Hz rTMS and physiotherapy
BackgroundPrevious studies showed that repetitive transcranial magnetic stimulation (rTMS) reduces spasticity after stroke. However, clinical...
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Effect of post-stroke spasticity on voluntary movement of the upper limb
BackgroundHemiparesis following stroke is often accompanied by spasticity. Spasticity is one factor among the multiple components of the upper motor...
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Impairments of the ipsilesional upper-extremity in the first 6-months post-stroke
BackgroundIpsilesional motor impairments of the arm are common after stroke. Previous studies have suggested that severity of contralesional arm...
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Spatial map** of posture-dependent resistance to passive displacement of the hypertonic arm post-stroke
BackgroundMuscles in the post-stroke arm commonly demonstrate abnormal reflexes that result in increased position- and velocity-dependent resistance...
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Role of Brain Derived Neurotrophic Factor and Related Therapeutic Strategies in Central Post-Stroke Pain
Brain-derived neurotrophic factor (BDNF) is vital for synaptic plasticity, cell persistence, and neuronal development in peripheral and central...
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Epidural stimulation of the cervical spinal cord for post-stroke upper-limb paresis
Cerebral strokes can disrupt descending commands from motor cortical areas to the spinal cord, which can result in permanent motor deficits of the...
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Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults
BackgroundGait training at fast speeds is recommended to reduce walking activity limitations post-stroke. Fast walking may also reduce gait kinematic...
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Technology-assisted assessment of spasticity: a systematic review
BackgroundSpasticity is defined as “a motor disorder characterised by a velocity dependent increase in tonic stretch reflexes (muscle tone) with...
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Reliability and diagnostic accuracy of corrected slack angle derived from 2D-SWE in quantitating muscle spasticity of stroke patients
BackgroundTo explore the feasibility of corrected slack angle acquired from two-dimensional shear wave elastography (2D-SWE) for quantitating the...
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Effect of transcutaneous spinal direct current stimulation on spasticity in upper motor neuron conditions: a systematic review and meta-analysis
Study designA systematic review and meta-analysis of clinical trials.
ObjectivesTo determine the effect of non-invasive transcutaneous spinal direct...
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Virtual reality—enhanced walking in people post-stroke: effect of optic flow speed and level of immersion on the gait biomechanics
BackgroundOptic flow—the apparent visual motion experienced while moving—is absent during treadmill walking. With virtual reality (VR), optic flow...
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Effects of Bilateral Assistance for Hemiparetic Gait Post-Stroke Using a Powered Hip Exoskeleton
Hemiparetic gait due to stroke is characterized by an asymmetric gait due to weakness in the paretic lower limb. These inter-limb asymmetries...
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Post-stroke hand gesture recognition via one-shot transfer learning using prototypical networks
BackgroundIn-home rehabilitation systems are a promising, potential alternative to conventional therapy for stroke survivors. Unfortunately,...
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Acceptability and impact on spasticity of a single session of upper extremity vibration in individuals with tetraplegia
Study designPre-post design; before and after vibration intervention.
ObjectivesTo explore effect of a focal, self-applied upper extremity (UE)...
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Botulinum Neurotoxins for Relief of Pain Associated with Spasticity
Spasticity is a common and disabling complication of stroke, multiple sclerosis, brain and spinal cord injury, neurogenetic disorders, and cerebral...
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Cerebellar deep brain stimulation for chronic post-stroke motor rehabilitation: a phase I trial
Upper-extremity impairment after stroke remains a major therapeutic challenge and a target of neuromodulation treatment efforts. In this open-label,...
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Quantitative measurement of resistance force and subsequent attenuation during passive isokinetic extension of the wrist in patients with mild to moderate spasticity after stroke
BackgroundSpasticity is evaluated by measuring the increased resistance to passive movement, primarily by manual methods. Few options are available...
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Peripheral magnetic theta burst stimulation to muscles can effectively reduce spasticity: a randomized controlled trial
BackgroundSpasticity is a common complication of many neurological diseases and despite contributing much disability; the available therapeutic...
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Movement kinematics and proprioception in post-stroke spasticity: assessment using the Kinarm robotic exoskeleton
BackgroundMotor impairment after stroke interferes with performance of everyday activities. Upper limb spasticity may further disrupt the movement...
