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Post-stroke Cognition is Associated with Stroke Survivor Quality of Life and Caregiver Outcomes: A Systematic Review and Meta-analysis
Disability arising from post-stroke cognitive impairment is a likely contributor to the poor quality of life (QoL) stroke survivors and their carers...
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Prediction of post-stroke cognitive impairment after acute ischemic stroke using machine learning
Background and objectivesPost-stroke cognitive impairment (PSCI) occurs in up to 50% of patients with acute ischemic stroke (AIS). Thus, the...
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DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
Post-stroke emotional disorders such as post-stroke anxiety and post-stroke depression are typical symptoms in patients with stroke. They are closely...
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CD13 facilitates immune cell migration and aggravates acute injury but promotes chronic post-stroke recovery
IntroductionAcute stroke leads to the activation of myeloid cells. These cells express adhesion molecules and transmigrate to the brain, thereby...
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Human-centered design of a novel soft exosuit for post-stroke gait rehabilitation
BackgroundStroke remains a major cause of long-term adult disability in the United States, necessitating the need for effective rehabilitation...
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Treadmill Exercise Enhances Post-Stroke Functional Recovery in Mice via the CX3CL1/CX3CR1 Signaling Pathway
To validate that treadmill exercise promotes neurofunctional recovery post ischemic stroke and to specifically explore the role of the CX3CL1/CX3CR1...
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Post-stroke aggressive behavior in patients wıth first-ever ischemic stroke: underlying clinical and imaging factors
BackgroundAggression is defined as a complex behavior consisting of a combination of sensory, emotional, cognitive and motor elements. We aimed to...
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Impairments of the ipsilesional upper-extremity in the first 6-months post-stroke
BackgroundIpsilesional motor impairments of the arm are common after stroke. Previous studies have suggested that severity of contralesional arm...
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Delayed plasma kallikrein inhibition fosters post-stroke recovery by reducing thrombo-inflammation
Activation of the kallikrein-kinin system promotes vascular leakage, inflammation, and neurodegeneration in ischemic stroke. Inhibition of plasma...
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Research Progress on the Mechanisms of Central Post-Stroke Pain: A Review
Central Post-Stroke Pain (CPSP) is a primary sequelae of stroke that can develop in the body part corresponding to the cerebrovascular lesion after...
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Corticospinal tract: a new hope for the treatment of post-stroke spasticity
Stroke is the third leading cause of death and disability worldwide. Post-stroke spasticity (PSS) is the most common complication of stroke but...
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Role of Brain Derived Neurotrophic Factor and Related Therapeutic Strategies in Central Post-Stroke Pain
Brain-derived neurotrophic factor (BDNF) is vital for synaptic plasticity, cell persistence, and neuronal development in peripheral and central...
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Ankle-targeted exosuit resistance increases paretic propulsion in people post-stroke
BackgroundIndividualized, targeted, and intense training is the hallmark of successful gait rehabilitation in people post-stroke. Specifically,...
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The IC87201 (a PSD95/nNOS Inhibitor) Attenuates Post- Stroke Injuries
N-methyl-D-aspartate receptor-dependent excitotoxicity is one of the most important mechanisms underlying stroke injury and the resulting neuronal...
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AMPA receptor modulation through sequential treatment with perampanel and aniracetam mitigates post-stroke damage in experimental model of ischemic stroke
The present study evaluates the effect of modulating α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor (AMPAR) by inhibiting them in the...
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Angiotensin II Type 2 Receptor Agonism Alleviates Progressive Post-stroke Cognitive Impairment in Aged Spontaneously Hypertensive Rats
Hypertension and aging are leading risk factors for stroke and vascular contributions to cognitive impairment and dementia (VCID). Most animal models...
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Time synchronization between parietal–frontocentral connectivity with MRCP and gait in post-stroke bipedal tasks
BackgroundIn post-stroke rehabilitation, functional connectivity (FC), motor-related cortical potential (MRCP), and gait activities are common...
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Transcranial direct current stimulation for post-stroke dysphagia: a meta-analysis
BackgroundStrokes may cause some swallowing difficulty or associated dysphagia in 25–80% of patients. This phenomenon has been linked to increased...
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Comparing the Symptomatology of Post-stroke Depression with Depression in the General Population: A Systematic Review
Previous research into the phenomenological differences of post-stroke depression (PSD) has typically focused on comparisons of symptom profiles...
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Real-Time Visual Kinematic Feedback During Overground Walking Improves Gait Biomechanics in Individuals Post-Stroke
Treadmill-based gait rehabilitation protocols have shown that real-time visual biofeedback can promote learning of improved gait biomechanics, but...