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Whole-genome characterization of avian picornaviruses from diarrheic broiler chickens co-infected with multiple picornaviruses in Iran
Gastrointestinal symptoms in poultry are caused by several factors, such as infecting viruses. Several avian picornaviruses can cause diarrhea in...
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Picornaviruses
The family Picornaviridae is one of the largest families of viruses and includes a large number of very small (pico: measuring small; rna: RNA virus)...
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Virtual Screening of Natural Compounds Targeting Proteases of Coronaviruses and Picornaviruses
Viral protease plays an essential role in viral replication and maturation. Therefore, the enzyme active site is an attractive target for the...
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Insert Stability and In Vivo Testing of MicroRNA-Detargeted Oncolytic Picornaviruses
Although a variety of oncolytic viruses under clinical investigation have proven to be safe, the overall efficacy of oncolytic viruses as...
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Wastewater-based epidemiology applied at the building-level reveals distinct virome profiles based on the age of the contributing individuals
BackgroundHuman viruses released into the environment can be detected and characterized in wastewater. The study of wastewater virome offers a...
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A proposed division of the family Picornaviridae into subfamilies based on phylogenetic relationships and functional genomic organization
The highly diverse virus family Picornaviridae presently comprises 68 approved genera with 158 species plus many unassigned viruses. In order to...
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A First-Hand Account of the Progression of Flavivirus Molecular Biology Research
Although yellow fever virus was the first positive-strand RNA virus to be studied, the first virus shown to be transmitted to humans by a mosquito...
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Persistent Detection of Cosavirus and Saffold Cardiovirus in Riachuelo River, Argentina
Cosaviruses (CoSV) and Saffold cardiovirus (SAFV) are novel members of the Picornaviridae family. The Matanza-Riachuelo river basin covers a total...
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Structural Alterations in Non-enveloped Viruses During Disassembly
The capsid shells of non-enveloped virusesNon-enveloped viruses can be categorized as large macromolecules constituted from protein building blocks,...
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Prevalence and genetic diversity in bovine parechovirus infecting Japanese cattle
The first bovine parechovirus (Bo_ParV) was reported in 2021, and currently, only two nearly complete genome sequences of Bo_ParV are available. In...
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Pathogen–Host Interaction and Its Associated Molecular Mechanism in HFMD Pathology and Immunology
Hand, foot, and mouth disease (HFMD) is caused by the enterovirus family, which includes EV-A71 and more than 10 other members. The disease involves...
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The 3' end of the coding region of senecavirus A contains a highly conserved sequence that potentially forms a stem-loop structure required for virus rescue
Senecavirus A (SVA) can cause a vesicular disease in swine. It is a positive-strand RNA virus belonging to the genus Senecavirus in the family Picornaviridae...
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Identification and genome characterization of novel parechovirus sequences from Hipposideros armiger in China
BackgroundBats were identified as a natural reservoir of emerging and re-emerging infectious pathogens threatening human health and life.
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Duck hepatitis A virus type 1 mediates cell cycle arrest in the S phase
BackgroundDuck hepatitis A virus type 1 (DHAV-1) is one of the most serious pathogens endangering the duck industry. However, there are few studies...
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The full genome characterization of avian encephalomyelitis virus, Iran: a vertical transmission case
Avian encephalomyelitis (AE) is an important infectious poultry disease worldwide that is caused by avian encephalomyelitis virus (AEV). The...
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Novel picornavirus (family Picornaviridae) from freshwater fishes (Perca fluviatilis, Sander lucioperca, and Ameiurus melas) in Hungary
In this study, a novel picornavirus (perchPV/M9/2015/HUN, GenBank accession no. MW590713) was detected in eight (12.9%) out of 62 faecal samples...
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Expanding the range of the respiratory infectome in Australian feedlot cattle with and without respiratory disease using metatranscriptomics
BackgroundBovine respiratory disease (BRD) is one of the most common diseases in intensively managed cattle, often resulting in high morbidity and...
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Introduction to Viruses
The viruses are too small to be seen with a light microscope. Their small size allows them to pass through filters used to retain bacteria in...
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Laboratory Diagnosis of Viral Diseases
The clinical manifestations may be protean and nonspecific for many of the viral infections. However, they provide a clue in diagnosing viral...
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Cryo-EM Studies of Virus-Antibody Immune Complexes
Antibodies play critical roles in neutralizing viral infections and are increasingly used as therapeutic drugs and diagnostic tools. Structural...
