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Showing 1-20 of 1,973 results

  1. Live attenuated pertussis vaccine for prevention and treatment of allergic airway inflammation in mice

    Live attenuated vaccines often have beneficial non-specific effects, protecting against heterologous infectious and non-infectious diseases. We have...

    Thomas Belcher, Saliha Ait-Yahia, ... Camille Locht in npj Vaccines
    Article Open access 23 June 2022

  3. Multivalent mRNA-DTP vaccines are immunogenic and provide protection from Bordetella pertussis challenge in mice

    Acellular multivalent vaccines for pertussis (DTaP and Tdap) prevent symptomatic disease and infant mortality, but immunity to Bordetella pertussis ...

    M. Allison Wolf, Joanne M. O’Hara, ... F. Heath Damron in npj Vaccines
    Article Open access 10 June 2024

  4. Evolution of Bordetella pertussis in the acellular vaccine era in Norway, 1996 to 2019

    We described the population structure of Bordetella pertussis ( B. pertussis ) in Norway from 1996 to 2019 and determined if there were evolutionary...

    Lin T. Brandal, Didrik F. Vestrheim, ... Ola B. Brynildsrud in European Journal of Clinical Microbiology & Infectious Diseases
    Article Open access 11 May 2022

  5. Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model

    Background

    The necessity of the tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine in adolescence and adults has been emphasized since...

    Kyu Ri Kang, Dong Ho Huh, ... ** Han Kang in BMC Immunology
    Article Open access 12 October 2021

  6. Bordetella pertussis whole cell immunization protects against Pseudomonas aeruginosa infections

    Whole cell vaccines are complex mixtures of antigens, immunogens, and sometimes adjuvants that can trigger potent and protective immune responses. In...

    Catherine B. Blackwood, Margalida Mateu-Borrás, ... Mariette Barbier in npj Vaccines
    Article Open access 10 November 2022

  7. High-resolution African HLA resource uncovers HLA-DRB1 expression effects underlying vaccine response

    How human genetic variation contributes to vaccine effectiveness in infants is unclear, and data are limited on these relationships in populations...

    Alexander J. Mentzer, Alexander T. Dilthey, ... Man**der S. Sandhu in Nature Medicine
    Article Open access 13 May 2024

  8. Molecular epidemiology of Bordetella pertussis and analysis of vaccine antigen genes from clinical isolates from Shenzhen, China

    Background

    Although pertussis cases globally have been controlled through the Expanded Programme on Immunization (EPI), the incidence of pertussis has...

    Shuang Wu, Qinghua Hu, ... **aolu Shi in Annals of Clinical Microbiology and Antimicrobials
    Article Open access 18 August 2021

  9. Effectiveness of experimental and commercial pertussis vaccines in the elimination of Bordetella pertussis isolates with different genetic profiles in murine model

    The aim of this study was to compare the elimination of Bordetella   pertussis clinical isolates, representing different genotypes in relation to...

    Marta Prygiel, Ewa Mosiej, ... Aleksandra Anna Zasada in Medical Microbiology and Immunology
    Article Open access 02 August 2021

  10. BCG-induced trained immunity enhances acellular pertussis vaccination responses in an explorative randomized clinical trial

    Acellular pertussis (aP) booster vaccines are central to pertussis immunization programs, although their effectiveness varies. The Bacille...

    Joshua Gillard, Bastiaan A. Blok, ... Dimitri A. Diavatopoulos in npj Vaccines
    Article Open access 17 February 2022

  11. A phase III randomized-controlled study of safety and immunogenicity of DTwP-HepB-IPV-Hib vaccine (HEXASIIL®) in infants

    A fully liquid hexavalent containing Diphtheria (D), Tetanus (T) toxoids, whole cell Pertussis (wP), Hepatitis B (Hep B), type 1, 2, 3 of inactivated...

    Hitt Sharma, Sameer Parekh, ... Sunil Gairola in npj Vaccines
    Article Open access 22 February 2024

  12. Quantitative Assay of B. pertussis Lipopolysaccharide

    We studied activity of Bordetella pertussis LPS in the LAL test. The mean activity of various series of LPS preparations obtained from B. pertussis ...

    M. R. Nazirov, A. V. Poddubikov, ... O. K. Parfenova in Bulletin of Experimental Biology and Medicine
    Article 01 April 2022

  13. Pertussis Vaccines

    The clinical characteristics of pertussis disease are highly dependent on the host’s basic immunity. Most if not all neonates and young infants...
    Ulrich Heininger in Pediatric Vaccines and Vaccinations
    Chapter 2021

  14. Vaccine Hesitancy and Refusal: History, Causes, Mitigation Strategies

    Vaccine hesitancyVaccine, hesitancy, referred to as the refusalVaccine, refusal or delayed uptake of vaccinationsVaccination despite their...
    Alessandro Siani in Integrated Science of Global Epidemics
    Chapter 2023

  16. Outer Membrane Vesicle Vaccine Platforms

    Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence...

    Francesca Micoli, Roberto Adamo, Usman Nakakana in BioDrugs
    Article Open access 05 October 2023

  17. Strategies of Vaccine Development

    The history of vaccines dates back to the fifteenth century, and since then, various vaccines have been discovered that have significantly reduced...
    Meenakshi Sachdeva, Sunil K. Arora in Biomedical Translational Research
    Chapter 2022

  18. Factors associated with malaria vaccine uptake in Nsanje district, Malawi

    Background

    Malaria remains a significant global health burden affecting millions of people, children under 5 years and pregnant women being most...

    Atusaye J. Simbeye, Save Kumwenda, ... Shehu S. Awandu in Malaria Journal
    Article Open access 17 April 2024

  19. Diphtheria: A Paradigmatic Vaccine-Preventable Toxigenic Disease with Changing Epidemiology

    Diphtheria is a paradigmatic example of a toxigenic infectious disease. It was Klebs who first identified Corynebacterium diphtheriae as the...
    Ivneet Kour, Lipika Singhal, Varsha Gupta in Recent Advances in Pharmaceutical Innovation and Research
    Chapter 2023

  20. Exploring the future adult vaccine landscape—crowded schedules and new dynamics

    Amidst the backdrop of the COVID-19 pandemic, vaccine innovation has garnered significant attention, but this field was already on the cusp of a...

    Charles H. Jones, Matthew P. Jenkins, ... Jane M. True in npj Vaccines
    Article Open access 09 February 2024
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