Search
Search Results
-
Public attitudes toward cloud computing and willingness to share personal health records (PHRs) and genome data for health care research in Japan
Japan’s government aims to promote the linkage of medical records, including medical genomic testing data and personal health records (PHRs), via...
-
Personal transcriptome variation is poorly explained by current genomic deep learning models
Genomic deep learning models can predict genome-wide epigenetic features and gene expression levels directly from DNA sequence. While current models...
-
Interference of the Human Genome with Nutrients
In this chapter, we will discuss the complex relation between our environment, diet and genome. Genes influence our response to diet, while...
-
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings
Deep learning methods have recently become the state of the art in a variety of regulatory genomic tasks
1 –6 , including the prediction of gene...
-
Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities
PurposeDue to the increasing application of genome analysis and interpretation in medical disciplines, professionals require adequate education....
-
Genome-Wide Principles of Gene Regulation
In this chapter, we will discuss about new principles of genome-wide gene regulation as obtained through data from Big Biology projects like ENCODE,...
-
The Human Genome Organisation (HUGO) and a vision for Ecogenomics: the Ecological Genome Project
BackgroundThe following outlines ethical reasons for widening the Human Genome Organisation’s (HUGO) mandate to include ecological genomics.
... -
The Human Genome and Its Variations
In this chapter, we will briefly describe the genetic adaption of anatomically modern humans due to migration from Africa to new geographic and...
-
Optical Genome Map**: A Machine-Based Platform in Cytogenomics
Optical genome map** (OGM) has generated excitement following decades of research and development. Now, commercially available technical platforms...
-
Survey of attitude to human genome modification in Nigeria
Gene editing and mitochondrial replacement therapy (MRT) are biotechnologies used to modify the host nuclear and mitochondrial DNA, respectively....
-
Genome-resolved metagenomics: a game changer for microbiome medicine
Recent substantial evidence implicating commensal bacteria in human diseases has given rise to a new domain in biomedical research: microbiome...
-
The interplay of ethics and genetic technologies in balancing the social valuation of the human genome in UNESCO declarations
This study investigates changes in the social valuation of the human genome over the more than 30 years since the establishment of the Human Genome...
-
Simulating the Genetics Clinic of the Future — whether undergoing whole-genome sequencing shapes professional attitudes
Whole-genome sequencing (WGS) can provide valuable health insight for research participants or patients. Opportunities to be sequenced are increasing...
-
-
Building cloud computing environments for genome analysis in Japan
This review article describes the current status of data archiving and computational infrastructure in the field of genomic medicine, focusing...
-
Cloud service checklist for academic communities and customization for genome medical research
In this paper, we present a cloud service checklist designed to help IT administrators or researchers in academic organizations select the most...
-
Whole Genome Sequencing of African Swine Fever
Next-generation sequencing (NGS) technologies have been powerfully applied in both research and clinical settings for the understanding and control...
-
A Guide to Genome-Wide Association Study Design for Diabetic Retinopathy
Diabetic retinopathy (DR) is the most common microvascular complication related to diabetes. There is evidence that genetics play an important role...
-
HLA Ty** and Mutation Calling from Normal and Tumor Whole Genome Sequencing Data with ALPHLARD-NT
HLA somatic mutations can alter the expression and function of HLA molecules, which in turn affect the ability of the immune system to recognize and...