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Lipid droplets in pathogen infection and host immunity
As the hub of cellular lipid metabolism, lipid droplets (LDs) have been linked to a variety of biological processes. During pathogen infection, the...
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Visualisation of Host–Pathogen Communication
The core of biomedical science is the use of laboratory techniques to support the diagnosis and treatment of disease in clinical settings. Despite...
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Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells
BackgroundThe action of mesenchymal stem cells (MSCs) is the subject of intense research in the field of regenerative medicine, including their...
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Clinical evaluation of metagenomic next-generation sequencing in unbiased pathogen diagnosis of urinary tract infection
BackgroundEarly availability of pathogen identification in urinary tract infections (UTIs) has critical importance in disease management. Metagenomic...
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Comparing automated surveillance systems for detection of pathogen-related clusters in healthcare settings
BackgroundDetection of pathogen-related clusters within a hospital is key to early intervention to prevent onward transmission. Various automated...
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Enhanced DNA and RNA pathogen detection via metagenomic sequencing in patients with pneumonia
BackgroundMetagenomic next-generation sequencing (mNGS) is an important supplement to conventional tests for pathogen detections of pneumonia....
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An integrated data analysis reveals distribution, hosts, and pathogen diversity of Haemaphysalis concinna
BackgroundHaemaphysalis concinna , carrying multiple pathogens, has attracted increasing attention because of its expanded geographical range and...
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Molecular pathogen screening of louse flies (Diptera: Hippoboscidae) from domestic and wild ruminants in Austria
BackgroundHippoboscid flies (Diptera: Hippoboscidae), also known as louse flies or keds, are obligate blood-sucking ectoparasites of animals, and...
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The Role of Host and Fungal Factors in the Commensal-to-Pathogen Transition of Candida albicans
Abstract Purpose of ReviewThe fungus Candida albicans has evolved to live in close association with warm-blooded hosts and is found frequently on...
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Contemporary exploitation of natural products for arthropod-borne pathogen transmission-blocking interventions
An integrated approach to innovatively counter the transmission of various arthropod-borne diseases to humans would benefit from strategies that...
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Host–pathogen associations revealed by genoty** of European strains of Anaplasma phagocytophilum to describe natural endemic cycles
BackgroundThe zoonotic intracellular alpha-proteobacterium Anaplasma phagocytophilum is a tick-transmitted pathogen. The associations between...
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Antibody indices of infectious pathogens from serum and cerebrospinal fluid in patients with schizophrenia spectrum disorders
IntroductionInfectious and immunological theories of schizophrenia have been discussed for over a century. Contradictory results for infectious...
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Review on infection control strategies to minimize outbreaks of the emerging pathogen Elizabethkingia anophelis
BackgroundElizabethkingia anophelis is a multi-drug resistant emerging opportunistic pathogen with a high mortality rate, causing...
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New insights into the impact of microbiome on horizontal and vertical transmission of a tick-borne pathogen
BackgroundThe impact of host skin microbiome on horizontal transmission of tick-borne pathogens , and of pathogen associated transstadial and...
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Phages are unrecognized players in the ecology of the oral pathogen Porphyromonas gingivalis
BackgroundPorphyromonas gingivalis (hereafter “ Pg ”) is an oral pathogen that has been hypothesized to act as a keystone driver of inflammation and...
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Comprehensive virome analysis of the viral spectrum in paediatric patients diagnosed with Mycoplasma pneumoniae pneumonia
BackgroundAmong hospitalized children suffering from community-acquired pneumonia, Mycoplasma pneumoniae (MP) is one of the most common pathogens....
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Induction of T-helper-17-cell-mediated anti-tumour immunity by pathogen-mimicking polymer nanoparticles
The effectivity of cancer immunotherapies is hindered by immunosuppressive tumour microenvironments that are poorly infiltrated by effector T cells...
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Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock
Most bacterial vaccines work for a subset of bacterial strains or require the modification of the antigen or isolation of the pathogen before vaccine...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and...
