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Genetically adjusted PSA levels for prostate cancer screening
Prostate-specific antigen (PSA) screening for prostate cancer remains controversial because it increases overdiagnosis and overtreatment of...
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Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter
Metastatic castration-resistant prostate cancer (mCRPC) is challenging to treat. Virus-like particles (VLPs), originating from JC polyomavirus...
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Optimizing anti-androgen treatment use among men with pathologic lymph-node positive prostate cancer treated with radical prostatectomy: the importance of postoperative PSA kinetics
BackgroundOptimal postsurgical management of prostate cancer (PCa) patients with nodal metastasis at the time of radical prostatectomy remains...
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15-year biochemical failure, metastasis, salvage therapy, and cancer-specific and overall survival rates in men treated with robotic radical prostatectomy for PSA-screen detected prostate cancer
BackgroundAn informed decision regarding a treatment option requires data on its long-term efficacy and side-effect profile. While the side-effects...
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Examination of prostate-specific antigen (PSA) screening in military and civilian men: analysis of the 2018 behavioral risk factor surveillance system
PurposeTo determine whether military men report different prostate-specific antigen (PSA) screening rates than civilian men and if shared...
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PSA response to antiandrogen withdrawal: a systematic review and meta-analysis
BackgroundAntiandrogen withdrawal (AAW) response is the paradoxical decrease in prostate-specific antigen (PSA) following the withdrawal of...
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Comparison of hypofractionation and standard fractionation for post-prostatectomy salvage radiotherapy in patients with persistent PSA: single institution experience
BackgroundHypofractionated post-prostatectomy radiotherapy is emerging practice, however with no randomized evidence so far to support it’s use....
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Microorganisms in Pathogenesis and Management of Psoriasis Arthritis (PsA)
Psoriatic arthritis is a chronic inflammatory disease with a destructive course that can lead to severe functional impairment. It is one of the...
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Detecting androgen receptor (AR), AR variant 7 (AR-V7), prostate-specific membrane antigen (PSMA), and prostate-specific antigen (PSA) gene expression in CTCs and plasma exosome-derived cfRNA in patients with metastatic castration-resistant prostate cancer (mCRPC) by integrating the VTX-1 CTC isolation system with the QIAGEN AdnaTest
BackgroundTherapies for metastatic castration-resistant prostate cancer (mCRPC) include targeting the androgen receptor (AR) with androgen receptor...
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Screening history and risk of death from prostate cancer: a nested case–control study within the screening arm of the Finnish Randomized Study of Screening for Prostate Cancer (FinRSPC)
PurposeWe assessed the risk of death from prostate cancer (PCa) in relation to men’s screening histories, i.e., screening attendance among men who...
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Oncological results and cancer control definition in focal therapy for Prostate Cancer: a systematic review
IntroductionFocal therapy (FT) is a promising alternative to whole-gland treatments for Localized Prostate Cancer. Ten different FT modalities have...
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The Physical Activity and Cancer Control (PACC) framework: update on the evidence, guidelines, and future research priorities
BackgroundWe proposed the Physical Activity and Cancer Control (PACC) framework in 2007 to help organise, focus, and stimulate research on physical...
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Dysbiosis of the Gut Microbiota in Patients with Psoriatic Arthritis is Closely Related to Lymphocyte Subsets and Cytokines
The purpose of this research was to characterize the microbiota of patients with psoriatic arthritis (PsA) and to compare the relationship between...
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High-intensity interval training versus moderate-intensity continuous training for localized prostate cancer under active surveillance: a systematic review and network meta-analysis
BackgroundHigh-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) have been increasingly adopted for localized...
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Challenges and opportunities in animal models of psoriatic arthritis
ObjectiveTo review the preparation, characteristics and research progress of different PsA animal models.
MethodsComputerized searches were...
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Beneficial effect of temporary methotrexate interruption on B and T cell responses upon SARS-CoV-2 vaccination in patients with rheumatoid arthritis or psoriatic arthritis
B and T cell responses were evaluated in patients with rheumatoid arthritis (RA) or psoriatic arthritis (PsA) after 1 or 2 weeks of methotrexate...
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Design of a tulobuterol patch with improved mechanical properties: effect of transdermal permeation enhancers on the release process of metal ligand-based acrylic pressure-sensitive adhesives
The aim of this study was to design a tulobuterol (TUL) patch with good penetration behavior and mechanical properties. Particular attention was paid...
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CD56 polysialylation promotes the tumorigenesis and progression via the Hedgehog and Wnt/β-catenin signaling pathways in clear cell renal cell carcinoma
BackgroundCD56 has been observed in malignant tumours exhibiting neuronal or neuroendocrine differentiation, such as breast cancer, small-cell lung...
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Epigenomics, Transcriptomics, and Translational Control in Prostate Cancer
Epigenetics refers to changes in gene expression that are not caused by changes in the underlying DNA sequence. It is now clear that epigenetic...