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A Low Omega-3 Index and High AA/EPA Ratio in American College Football Players are Both Improved Following 5 Weeks of DHA-Rich Algae Oil Supplementation
PurposeMany athletes are deficient in long chain omega-3 polyunsaturated fatty acids (LC n-3 PUFA). A consequent low Omega-3 Index (O3I) and high...
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Omega-3 Attenuates Disrupted Neurotransmission and Partially Protects Metabolic Dysfunction Caused by Obesity in Wistar Rats
Omega-3 (n3) is a polyunsaturated fatty acid well known for its anti-inflammatory and neuroprotective properties. Obesity is linked to chronic...
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The Ratio of Omega-6/Omega-3 Fatty Acid: Implications and Application as a Marker to Diabetes
Omega-3 and omega-6 groups of polyunsaturated fatty acids (PUFA) are non-interconvertible and metabolically and functionally different, with key... -
Omega-3 Effects on Ligature-Induced Periodontitis in Rats with Fructose-Induced Metabolic Syndrome
Both periodontal disease (PD) and metabolic syndrome (MS) represent disorders of concern worldwide. Current evidence indicates that PD and MS might...
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The Role of Omega-3 Fatty Acids in Alzheimer’s Disease Prevention and Therapy
Omega-3 fatty acids represent a group of fatty acids characterized by the double bond located at the third carbon atom from the terminal methyl end... -
Effect of Omega-3 fatty acids supplementation on serum level of C-reactive protein in patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
BackgroundOmega-3 may alleviate the severity of coronavirus disease 2019 (COVID-19) by reducing the C-reactive protein (CRP) level, a marker for...
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Impacts of Omega-3 Fatty Acids, Natural Elixirs for Neuronal Health, on Brain Development and Functions
Omega-3 fatty acids play a seminal role in maintaining the structural and functional integrity of the nervous system. These specialized molecules... -
Cognitive impact of multidomain intervention and omega 3 according to blood Aβ42/40 ratio: a subgroup analysis from the randomized MAPT trial
BackgroundIn MAPT (Multidomain Alzheimer Preventive Trial), a cognitive effect of multidomain intervention (MI) was showed in non-demented subjects...
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Evaluating the distinct pleiotropic effects of omega-3 fatty acids on type 2 diabetes mellitus: a mendelian randomization study
BackgroundObservational studies and conventional Mendelian randomization (MR) studies showed inconclusive evidence to support the association between...
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Omega-3 in the Subjective Betterment of Mood and Sleep Disturbances Induced by Hormone Therapy in Women with Breast Cancer: A Pilot, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial
BackgroundThis study was performed to investigate the effect of omega-3 administration on the treatment of mood and sleep problem induced by...
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Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS
We examined associations between lipidomic profiles and incident ischemic stroke in the REasons for Geographic and Racial Differences in Stroke...
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Fish oil omega-3 Fatty Acids Alleviate Postoperative delirium-like Behavior in aged mice by Attenuating Neuroinflammation and Oxidative Stress
Postoperative delirium (POD) is a common and serious neuropsychiatric syndrome among older patients, and lacks effective therapies. Omega-3 fatty...
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The Ratio of Omega-6/Omega-3 Fatty Acid: Implications and Application as a Marker to Diabetes
Omega-3 and omega-6 groups of polyunsaturated fatty acids (PUFA) are non-interconvertible and metabolically and functionally different, with key... -
Omega-3 Polyunsaturated Fatty Acids Protect Neurological Function After Traumatic Brain Injury by Suppressing Microglial Transformation to the Proinflammatory Phenotype and Activating Exosomal NGF/TrkA Signaling
The transformation of microglia to a pro-inflammatory phenotype at the site of traumatic brain injury (TBI) drives the progression of secondary...
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Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders
In adulthood, depressionDepression is the most common psychiatric disorder and is projected to become the highest cause of disease burden by 2030.... -
Omega-3 fatty acids attenuate cardiovascular effects of short-term exposure to ambient air pollution
BackgroundExposure to air pollution is associated with elevated cardiovascular risk. Evidence shows that omega-3 polyunsaturated fatty acids (omega-3...
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The effect of omega-3 fatty acid supplementation on clinical and biochemical parameters of critically ill patients with COVID-19: a randomized clinical trial
BackgroundOmega-3 polyunsaturated fatty acids (n3-PUFAs) may exert beneficial effects on the immune system of patients with viral infections. This...
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Omega-3 Polyunsaturated Fatty Acids and Cancer
Naturally occurring fatty acids can be classified into three categories based on the number of double bonds in side-chain. These are saturated fatty... -
DHA supplementation and pregnancy complications
Docosahexaenoic acid (DHA) supplementation is recommended for women during pregnancy because of its neurological, visual, and cognitive effects....