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QbD Based Formulation Development and Optimisation of Ozenoxacin Topical Nano-Emulgel and Efficacy Evaluation Using Impetigo Mice Model
To formulate and optimize Ozenoxacin nano-emulsion using Quality by Design (QbD) concept by means of Box–Behnken Design (BBD) and converting it to a...
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A novel chitosan-based doxepin nano-formulation for chemotherapy-induced oral mucositis: a randomized, double-blinded, placebo-controlled clinical trial
ObjectivesConsidering the prevalence of oral mucositis, we aimed to use the analgesic effects of doxepin with chitosan’s antimicrobial and...
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Unravelling therapeutic potential and nano formulation approaches of farnesol, a bioactive sesquiterpene
Historically natural compounds and their structural equivalents have significantly contributed to pharmacotherapy. Sesquiterpenes, the C15-terpenoids...
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Nano Drug Delivery Strategies for an Oral Bioenhanced Quercetin Formulation
Quercetin, a naturally occurring flavonoid, has been credited with a wide spectrum of therapeutic properties. However, the oral use of quercetin is...
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Curcumin-resveratrol nano-formulation counteracting hyperammonemia in rats
Malnutrition and low dietary protein intake could be risk factors for develo** peripheral and central hyperammonemia, especially in pediatrics....
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Development of a novel rapamycin loaded nano- into micro-formulation for treatment of lung inflammation
It has recently emerged that drugs such as the mTOR inhibitor rapamycin (Rapa) may play a key role in the treatment of airway inflammation associated...
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Photothermal Therapy Mediated Hybrid Membrane Derived Nano-formulation for Enhanced Cancer Therapy
Emodin is applied as an antitumor drug in many tumor therapies. However, its pharmacology performances are limited due to its low solubility. Herein,...
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Binary Nano-inhalant Formulation of Icariin Enhances Cognitive Function in Vascular Dementia via BDNF/TrkB Signaling and Anti-inflammatory Effects
Vascular dementia (VaD) has a serious impact on the patients’ quality of life. Icariin (Ica) possesses neuroprotective potential for treating VaD,...
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Potent anthelmintic activity of a colloidal nano-silver formulation (Silversol®) against the model worm Caenorhabditis elegans
ObjectiveIn the background of a very small number of effective anthelmintics available today with a narrow activity spectrum, and a rise in...
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Formulation and Characterization of Silibinin Entrapped Nano-Liquid Crystals for Activity against Aβ1-42 Neurotoxicity in In-Vivo Model
Silibinin (SIL) Encapsulated Nanoliquid Crystalline (SIL-NLCs) particles were prepared to study neuroprotective effect against amyloid beta (Aβ 1-42 )...
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Utility of Silver-nanoparticles for Nano-fluorimetric Determination of Vancomycin Hydrochloride in Pharmaceutical Formulation and Biological Fluids: Greenness Assessment
Vancomycin hydrochloride (VANH) is a glycopeptide antibiotic commonly employed in the prophylaxis and therapy of various gram-positive bacterial...
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A Full Factorial Design to Optimize Aminexil Nano Lipid Formulation to Improve Skin Permeation and Efficacy Against Alopecia
Aminexil (AMX) is considered to be one of the most widely used hair growth promoters. Nanostructured lipid carriers (NLC) are employed to increase...
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Development and in vitro/in vivo evaluation of a nanosponge formulation loaded with Boswellia carterii oil extracts for the enhanced anti-inflammatory activity for the management of respiratory allergies
PurposeIn several nations, it has been known that Boswellia carterii (BC) plants have a long history of usage as an anti-inflammatory medicine. Our...
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Routes of Nano-drug Administration and Nano-based Drug Delivery System and Toxicity
In recent years, nanotechnology has grown significantly with enormous potential in technology in research and medicine to improve tissue engineering,...
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Anti-diabetic Nano-formulation from Herbal Source
Diabetes is one amongst the chronic metabolic diseases affecting millions of people across the world. Apart from proper selection of drugs and doses,...
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Toxicity Issues of Nanoparticles in the Delivery of Phytoconstituents and Cosmeceuticals
Science of combining active pharmaceutical ingredients with the cosmetics for the purpose of therapeutic effects in addition to beautifying,...
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Pattern recognition receptors and their nano-adjuvants for cancer immunotherapy
BackgroundPattern recognition receptors (PRRs) are crucial immune modulators that orchestrate innate and adaptive immune systems for the regulation...
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Thymoquinone-loaded self-nano-emulsifying drug delivery system against ischemia/reperfusion injury
In the present study, a self-nano-emulsifying drug delivery system (SNEDDS) was developed to evaluate the efficiency of thymoquinone (TQ) in hepatic...
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Nano-composite system of traditional Chinese medicine for ocular applications: molecular docking and three-dimensional modeling insight for intelligent drug evaluation
The absorption of drugs was impeded in the posterior part of the eye due to the special structure. In addition, it was crucial to comprehend...
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Biotechnological Approaches in Infectious Diseases
Infectious conditions have a significant influence on the occurrence of illness and death worldwide. The management of human immunodeficiency virus...