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Genus Mycobacterium and Mycobacterium tuberculosis
The genus Mycobacterium included in the family Mycobacteriaceae consists of non-motile, non-spore-forming and aerobic bacilli. They are slightly...
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Evolution and Molecular Characteristics of Mycobacterium tuberculosis and Mycobacterium bovis
In the last decade, a major genomicsGenomics revolution took place in life and health sciences that shed light on the biologyBiology and...
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Energy Pathways in Mycobacterium Tuberculosis
Mycobacterium tuberculosisMycobacterium tuberculosis (M. tb) is responsible for the infectious illness tuberculosis (TB), which has a very high...
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Mycobacterium leprae, Mycobacterium lepraemurium and Non-tuberculosis Mycobacteria
Mycobacterium leprae is the causative agent of leprosy, a chronic granulomatous disease primarily affecting the skin and peripheral nervous system....
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Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy
BackgroundThe pathogen responsible for tuberculosis is called Mycobacterium tuberculosis. Its interaction with macrophages has a significant impact...
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Important Targets and Inhibitors of Mycobacterium tuberculosis
Tuberculosis (TB) is a global health issue. Millions of TB-infected patients remain undiagnosed, untreated, or improperly treated, leading to...
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Photodynamic Inactivation of Mycobacterium tuberculosis Using Alluminium Phthalocyanine
In a series of in vitro experiments, the optimum regimes of laser treatment were determined for effective photodynamic inactivation of Mycobacterium...
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Exploring and exploiting the host cell autophagy during Mycobacterium tuberculosis infection
Tuberculosis, caused by Mycobacterium tuberculosis , is a fatal infectious disease that prevails to be the second leading cause of death from a single...
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Development of a multiplex droplet digital PCR method for detection and monitoring of Mycobacterium tuberculosis and drug-resistant tuberculosis
BackgroundThe prevalence of multidrug-resistant tuberculosis (MDR-TB) among Korean tuberculosis patients is about 4.1%, which is higher than the OECD...
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Infection of Fetal Membranes with Mycobacterium tuberculosis and Tissue Processing to Isolate RNA for Expression Analysis
This chapter outlines the methodology employed to infect the chorionic and amniotic membranes with Mycobacterium tuberculosis during pregnancy....
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The future of CRISPR in Mycobacterium tuberculosis infection
Clustered Regularly Interspaced Short Palindromic repeats (CRISPR)-Cas systems rapidly raised from a bacterial genetic curiosity to the most popular...
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Identification of Poly(ADP-ribose) Polymerase 9 (PARP9) as a Potent Suppressor for Mycobacterium tuberculosis Infection
ADP-ribosylation is a reversible and dynamic post-translational modification mediated by ADP-ribosyltransferases (ARTs). Poly(ADP-ribose) polymerases...
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P-Type ATPases: A Relevant Component in Mycobacterium tuberculosis Viability
Tuberculosis (TB) is an infectious diseaseDiseaseInfectious that represents an important cause of worldwide deathDeath. Despite the treatments used...
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Tyrosine inhibits the Mycobacterium tuberculosis protein tyrosine phosphatase MptpA
The catalytic action of the low-molecular weight protein tyrosine phosphatase (MptpA), expressed by Mycobacterium tuberculosis , is known to be...
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Prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation comparing tuberculin skin test and interferon-gamma release assay
The aim of this study was to evaluate the prevalence of latent Mycobacterium tuberculosis infection in hematopoietic stem cell transplantation...
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Tuberculosis
Tuberculosis is one of the major global health concerns associated with a high morbidity and mortality rate. Pulmonary tuberculosis may remain latent...
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Insidious transmission of Mycobacterium tuberculosis in Ordos, China: a molecular epidemiology study
BackgroundIn this study, we conducted this population-based study to evaluate the genetic diversity and clustering rate of Mycobacterium tuberculosis ...
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Abbott realtime MTB assay for detecting Mycobacterium tuberculosis complex in respiratory specimens: a cost-benefit analysis
PurposeMolecular screening for Mycobacterium tuberculosis (MTB) can lead to rapid empirical treatment inception and reduce hospitalization time and...
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Prevalence and genetic basis of Mycobacterium tuberculosis resistance to pretomanid in China
BackgroundPretomanid is a key component of new regimens for the treatment of drug-resistant tuberculosis (TB) which are being rolled out globally....
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Transition between Mycobacterium tuberculosis and nontuberculous mycobacteria in recurrent “tuberculosis” patients
Recurrence of tuberculosis (TB) is still a key issue in the control of tuberculosis. The presence of nontuberculous mycobacteria (NTM) complicates...
