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Efficacy of an oral formulation of afoxolaner and milbemycin oxime against Tunga penetrans in naturally infected dogs
BackgroundThe sand flea Tunga penetrans is one of the agents of tungiasis, an important parasitic skin disease affecting humans and several...
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Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) for the prevention of heartworm disease (Dirofilaria immitis) in client-owned dogs in the USA
BackgroundDirofilaria immitis, a globally distributed filarial parasite of dogs, is known to cause serious or fatal cardiopulmonary disease....
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Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) against natural flea and tick infestations on dogs presented as veterinary patients in Europe
BackgroundA pivotal randomised, blinded, positive-controlled, multicentre, European field study was conducted to evaluate the effectiveness and...
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Field study to investigate the effectiveness and safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) against natural intestinal nematode infections in dogs presented as veterinary patients in Europe
BackgroundA randomised, blinded, positive controlled, multicentre, Good Clinical Practice-compliant, pivotal field study was conducted to evaluate...
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Effectiveness of Credelio® Plus, a novel chewable tablet containing milbemycin oxime and lotilaner for the treatment of larval and immature adult stages of Toxocara canis in experimentally infected dogs
BackgroundThe ascarid, Toxocara canis, is a common and important zoonotic intestinal nematode parasite that infects dogs globally. An effective...
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Long-term and acute safety of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) in juvenile and adult dogs
BackgroundThe combination of milbemycin oxime (MO) and lotilaner (Credelio ® Plus) is a novel systemic endectocide that provides month-long...
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Effectiveness of a novel orally administered combination drug product containing milbemycin oxime and lotilaner (Credelio® Plus) for the treatment of larval and immature adult stages of Ancylostoma caninum in experimentally infected dogs
BackgroundThe hookworm, Ancylostoma caninum , is a common and important zoonotic intestinal nematode parasite that infects dogs globally. Both the...
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Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio®) in the treatment of sarcoptic mange caused by Sarcoptes scabiei mite infestations in dogs
BackgroundInfestation with Sarcoptes scabiei in dogs is a debilitating disease if left untreated and is transmissible to humans. Two field studies...
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Efficacy of milbemycin oxime/afoxolaner chewable tablets (NEXGARD SPECTRA®) against Capillaria aerophila and Capillaria boehmi in naturally infected dogs
BackgroundCapillaria aerophila and Capillaria boehmi parasitize the respiratory system of wild and domestic carnivores. Capillaria aerophila ...
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Gastrointestinal helminths in dogs: occurrence, risk factors, and multiple antiparasitic drug resistance
Helminth infections are detrimental to the overall health of dogs; therefore, this study aimed to identify antiparasitic-resistant helminths and...
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Preventive efficacy of six monthly oral doses of Simparica Trio®, Heartgard® Plus, and Interceptor® Plus against a macrocyclic lactone-resistant strain (ZoeLA) of heartworm (Dirofilaria immitis) in dogs
BackgroundAdministration of four to six consecutive monthly doses of 24 µg/kg moxidectin alone shows high effectiveness in preventing the maturation...
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Comparative preventive efficacy of ProHeart® 12, Heartgard® Plus and Interceptor® Plus against a macrocyclic lactone-resistant strain (JYD-34) of heartworm (Dirofilaria immitis) in dogs
BackgroundThe current studies compared ProHeart ® 12, Heartgard ® Plus and Interceptor ® Plus for preventive efficacy against JYD-34, a macrocyclic...
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A case of a dog refractory to different treatments for pulmonary capillariasis
Pulmonary capillariasis is a parasitic disease caused by the nematode Eucoleus aerophilus which affects wild and domestic carnivores. Currently,...
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Heartworm disease in domestic dogs in Estonia: indication of local circulation of the zoonotic parasite Dirofilaria immitis farther north than previously reported
BackgroundThe mosquito-borne zoonotic parasite Dirofilaria immitis continues to spread northwards in Europe. This parasite can cause potentially...
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Ophthalmic Thelazia callipaeda infections: first feline and new canine imported cases in Germany
The first case of feline ocular Thelazia callipaeda infection and two new canine imported infections in West Germany are here described. The three...
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Retrospective analyses of heartworm (Dirofilaria immitis) disease and ectoparasite preventive medication compliance in veterinary practices in the USA
BackgroundCompliance failure with administration of heartworm (HW) disease preventives has been reported as the main contributor to HW disease...
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Efficacy of a formulation of sarolaner/moxidectin/pyrantel (Simparica Trio®) for the prevention of Thelazia callipaeda canine eyeworm infection
BackgroundFor a long time known as the oriental eyeworm, Thelazia callipaeda is a zoonotic nematode that infects the eyes of a wide range of...
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Angiostrongylus vasorum in a Red Panda (Ailurus fulgens): Clinical Diagnostic Trial and Treatment Protocol
PurposeThe literature refers that Angiostrongylus vasorum should always be considered in the differential diagnosis of respiratory diseases in...
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Heartworm (Dirofilaria immitis) in carnivores kept in zoos in Texas, USA: risk perception, practices, and antigen detection
BackgroundDirofilaria immitis is the causative agent of heartworm disease in wild and domestic canids, felids, and mustelids. Recent studies...
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Anthelmintic efficacy of nitazoxanide in dogs naturally infected with Toxocara canis
Toxocara canis ( T. canis ) is a gastrointestinal nematode in dogs, and its larvae also infect humans, causing severe larval migratory disease....