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Tree based models for classification of membrane and secreted proteins in heart
Computational differentiation of membrane and secreted proteins is one of the challenging and interesting topics in bioinformatics. It is a laborious...
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Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
The Popeye domain containing (POPDC) genes encode sarcolemma-localized cAMP effector proteins. Mutations in blood vessel epicardial substance ( BVES )...
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Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system
BackgroundHomozygous CD59-deficient patients manifest with recurrent peripheral neuropathy resembling Guillain-Barré syndrome (GBS), hemolytic anemia...
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The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy
Despite significant advances in our understanding of tumourigenesis and cancer therapeutics, cancer continues to account for 30% of worldwide deaths....
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Epitope vaccine design for Toxoplasma gondii based on a genome-wide database of membrane proteins
BackgroundThere is presently no effective and safe vaccine for Toxoplasma gondii for humans. The study described here was designed to search for a...
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Evaluating Cell Membrane Localization and Intracellular Transport of Proteins by Biotinylation
Protein translocation to the cell membrane and transport through intracellular compartments are dynamic processes frequently altered in cancer cells....
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Role of BCR and FNBP1 Proteins in Phagocytosis as a Model of Membrane Rearrangements with Chronic Myelogenous Leukemia
Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm resulting from the emergence of abnormal hematopoietic stem cells carrying a...
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Obtention of Dengue Virus Membrane Proteins and Role for Virus Assembly
The four serotypes of dengue virus (DENV), belonging to the genus Flavivirus in the family Flaviviridae, are the leading cause of arboviral diseases...
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The Amphipathic Helix in Visual Cycle Proteins: A Review
The visual cycle is a complex biological process that involves the sequential action of proteins in the retinal pigment epithelial (RPE) cells and...
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Microsporidia Have a Peculiar Outer Membrane with Exterior Cytoplasmic Proteins
PurposeMost eukaryotic cells have a plasma membrane with glycoproteins on the outer leaflet and cytoplasmic proteins on the inner leaflet. However,...
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Fluorescence Lifetime and Cross-correlation Spectroscopy for Observing Membrane Fusion of Liposome Models Containing Synaptic Proteins
Watching events of membrane fusionMembrane fusion in real time and distinguishing between intermediate steps of these events is useful for...
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Presynaptic Cytomatrix Proteins
The Cytomatrix Assembled at the active Zone (CAZ) of a presynaptic terminal displays electron-dense appearance and defines the center of the synaptic...
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The Art of Viral Membrane Fusion and Penetration
As obligate pathogens, viruses have developed diverse mechanisms to deliver their genome across host cell membranes to sites of virus replication....
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Membrane organization by tetraspanins and galectins shapes lymphocyte function
Immune receptors are not randomly distributed at the plasma membrane of lymphocytes but are segregated into specialized domains that function as...
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SNARE Proteins in Synaptic Vesicle Fusion
Neurotransmitters are stored in small membrane-bound vesicles at synapses; a subset of synaptic vesicles is docked at release sites. Fusion of docked...
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Western Blotting of Membrane-Bound Proteins in Yarrowia lipolytica
With the discovery of Western blotting as first described by Towbin et al. in 1979, the transfer and visualization of electrophoretically separated...
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Cycle-dependent sex differences in expression of membrane proteins involved in cerebrospinal fluid secretion at rat choroid plexus
BackgroundFemale sex is a known risk factor of brain disorders with raised intracranial pressure (ICP) and sex hormones have been suggested to alter...
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A Simple and Low-cost Preliminary Quantification of Target Membrane Protein in Single Cells
To study the heterogeneity of target membrane proteins in single cells with cellular integrity, we proposed a simple and low-cost method to obtain...
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Membrane Vesicles of Clostridioides difficile and Other Clostridial Species
Membrane vesicles are secreted by growing bacterial cells and are important components of the bacterial secretome, with a role in delivering effector...
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Transmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles
A transmembrane (TMEM) protein with an unknown function is a type of membrane-spanning protein expressed in the plasma membrane or the membranes of...
