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Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
The Popeye domain containing (POPDC) genes encode sarcolemma-localized cAMP effector proteins. Mutations in blood vessel epicardial substance ( BVES )...
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Computational Fluid–Structure Interaction Study of a New Wave Membrane Blood Pump
PurposeWave membrane blood pumps (WMBP) are novel pump designs in which blood is propelled by means of wave propagation by an undulating membrane. In...
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Tree based models for classification of membrane and secreted proteins in heart
Computational differentiation of membrane and secreted proteins is one of the challenging and interesting topics in bioinformatics. It is a laborious...
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Membrane Mechanisms of Tremor
Tremor is one of the most common hyperkinetic movement disorders. Tremors can be of many different types, and the etiopathogenesis is very diverse...
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Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death
Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to other types of cell death. Elucidating additional...
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Membrane organization by tetraspanins and galectins shapes lymphocyte function
Immune receptors are not randomly distributed at the plasma membrane of lymphocytes but are segregated into specialized domains that function as...
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The Art of Viral Membrane Fusion and Penetration
As obligate pathogens, viruses have developed diverse mechanisms to deliver their genome across host cell membranes to sites of virus replication....
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FLIM-FRET Protein-Protein Interaction Assay
Fluorescence lifetime imaging performed under FRET conditions between two interacting molecules is a sensitive and robust way to quantify...
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Resting membrane state as an interplay of electrogenic transporters with various pumps
In this study, a new idea that electrogenic transporters determine cell resting state is presented. The previous assumption was that pumps,...
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An ESIPT-Based Fluorescent Probe for Wash-Free Cell Membrane Imaging
The cell membrane tracking is important for studying the membrane function and diagnosing membrane-related diseases, so the development of...
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Kinin B1 receptor and TLR4 interaction in inflammatory response
ObjectiveWe aimed to broaden our understanding of a potential interaction between B1R and TLR4, considering earlier studies suggesting that...
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Membrane potential dynamics of C5a-stimulated neutrophil granulocytes
Neutrophil granulocytes play a crucial role in host defense against invading pathogens and in inflammatory diseases. The aim of this study was to...
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Role of BCR and FNBP1 Proteins in Phagocytosis as a Model of Membrane Rearrangements with Chronic Myelogenous Leukemia
Chronic myelogenous leukemia (CML) is a myeloproliferative neoplasm resulting from the emergence of abnormal hematopoietic stem cells carrying a...
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A Comprehensive Review of Membrane Transporters and MicroRNA Regulation in Alzheimer’s Disease
Alzheimer’s disease (AD) is a distressing neurodegenerative condition characterized by the accumulation of amyloid-beta (Aβ) plaques and tau tangles...
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Targeting Outer Membrane to Tackle Multidrug-Resistant Bacterial Pathogens
Infections caused due to Gram-negative bacterial pathogens, under community as well as nosocomial settings, are increasing affecting healthcare...
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Controlling Cell Membrane Potential with Static Nonuniform Magnetic Fields
The coordinated activity of a myriad of ion channels in a cell is a spectacular biological and physical phenomenon. Understanding mechanisms...
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LAMC2 mitigates ER stress by enhancing ER-mitochondria interaction via binding to MYH9 and MYH10
Highly proliferative and metastatic tumors are constantly exposed to both intrinsic and extrinsic factors that induce adaptation to stressful...
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The Mechanisms of Interaction Between Extracellular Vesicles and Target Cells
The ability of extracellular vesicles (EVs) to transmit signals on the cell surface and/or transfer their contents from donor to recipient cells to...
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Extracellular high molecular weight α-synuclein oligomers induce cell death by disrupting the plasma membrane
α-Synuclein (αS), the causative protein of Parkinson’s disease and other α-synucleinopathies, aggregates from a low molecular weight form (LMW-αS) to...
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