Search
Search Results
-
Coronavirus vaccine development: from SARS and MERS to COVID-19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which...
-
Successful implementation of ITN distribution through health facilities in Ghana
BackgroundGlobal efforts to reduce malaria burden include distribution of insecticide-treated mosquito nets through mass campaigns and routine...
-
Prophylactic strategies to control chikungunya virus infection
Chikungunya virus (CHIKV) is a (re)emerging arbovirus and the causative agent of chikungunya fever. In recent years, CHIKV was responsible for a...
-
Vaccines and Oncolytic Virus for the Treatment of Lung Cancer
Lung cancer is the most prevalent cause of cancer deaths in men and women, with a 5-year survival rate of fewer than 15% due to late-stage diagnosis...
-
Novel Cancer Treatment Using Oncolytic Virus Therapy
Oncolytic viruses are a unique group of viruses that – either naturally or through genetic modification – induce the destruction of cancer cells....
-
Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts
Memory B cells persist for a lifetime and rapidly differentiate into antibody-producing plasmablasts and plasma cells upon antigen re-encounter. The...
-
SARS-CoV-2 RNA polymerase as target for antiviral therapy
A new human coronavirus named SARS-CoV-2 was identified in several cases of acute respiratory syndrome in Wuhan, China in December 2019. On March 11...
-
Elevated expansion of follicular helper T cells in peripheral blood from children with acute measles infection
BackgroundMeasles outbreaks have threatened the global elimination and eradication of measles in recent years. Measles virus (MeV)-specific...
-
Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a...
-
Measles outbreak investigation in Artuma Fursi Woreda, Oromia Zone, Amhara Region, Ethiopia, 2018: a case control study
ObjectiveTo confirm the existence of Outbreak, describe cases in person, place and time, and identify determinants of the outbreak. Unmatched case...
-
Incomplete childhood vaccination and associated factors among children aged 12–23 months in Gondar city administration, Northwest, Ethiopia 2018
ObjectiveDespite the fact that immunization services are offered free of charge in Ethiopia but the coverage of complete vaccination is still low....
-
Physicochemical and Preclinical Evaluation of a Novel Buccal Measles Vaccine
The aim of this study is to develop an orally disintegrating film (ODF) containing a microparticulate measles vaccine formulation for buccal...
-
Transfer of maternal immunity and programming of the newborn immune system
As placental mammals, the pregnant women and the fetus have intense and prolonged interactions during gestation. There is increasing evidence that...
-
Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies
In today’s global economy and affordable vacation travel, it is increasingly important that visitors to another country and their physician be...
-
Fc Receptors as Adaptive Immunoreceptors
Most biological activities of antibodies depend on their ability to engage Receptors for the Fc portion of immunoglobulins (FcRs) on a variety of...
-
Immune Signatures and Systems Biology of Vaccines
Vaccines represent a strategic successful tool to prevent or contain diseases with high morbidity or mortality. However, despite the extensive and...
-
Oncolytic viral therapy of malignant glioma
Novel approaches to treatment of malignant glioma, the most frequently occurring primary brain tumor, have included the use of a wide range of...
-
Measles Virus-Induced Immunosuppression
Immunosuppression is the major cause of infant death associated with acute measles and therefore of substantial clinical importance. Major hallmarks...
-
Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability
Dendritic cells (DC) are potent antigen-presenting cells that play an important role in inducing primary antigen-specific immune responses. However,...
-
Measles infection of the central nervous system
Central nervous system (CNS) complications occuring early and late after acute measles are serious and often fatal. In spite of functional...