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Immune-mediated cerebellitis following SARS-CoV-2 infection—a case report and review of the literature
The coronavirus disease 2019 (COVID-19) can be associated with a wide variety of neurological manifestations. Some of these manifestations might...
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Public Health Advocacy
Public health advocacy refers to gaining political commitment for particular health goals or programs. It targets decision-makers, policymakers, and...
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Measles outbreak investigation in Artuma Fursi Woreda, Oromia Zone, Amhara Region, Ethiopia, 2018: a case control study
ObjectiveTo confirm the existence of Outbreak, describe cases in person, place and time, and identify determinants of the outbreak. Unmatched case...
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Novel Cancer Treatment Using Oncolytic Virus Therapy
Oncolytic viruses are a unique group of viruses that – either naturally or through genetic modification – induce the destruction of cancer cells....
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Successful implementation of ITN distribution through health facilities in Ghana
BackgroundGlobal efforts to reduce malaria burden include distribution of insecticide-treated mosquito nets through mass campaigns and routine...
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Coronavirus vaccine development: from SARS and MERS to COVID-19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which...
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Prophylactic strategies to control chikungunya virus infection
Chikungunya virus (CHIKV) is a (re)emerging arbovirus and the causative agent of chikungunya fever. In recent years, CHIKV was responsible for a...
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Immune-mediated entities of (primary) focal segmental glomerulosclerosis
Focal segmental glomerulosclerosis (FSGS) represents a glomerular scar formation downstream of various different mechanisms leading to podocytopathy...
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Recent Developments on Therapeutic and Diagnostic Approaches for COVID-19
The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made a...
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Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients
BackgroundNew-generation cell-based assays have demonstrated a robust association of serum autoantibodies to full-length human myelin oligodendrocyte...
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Glycoproteins of HHV-6A and HHV-6B
Recently, human herpesvirus 6A and 6B (HHV-6A and HHV-6B) were classified into distinct species. Although these two viruses share many similarities,...
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Physicochemical and Preclinical Evaluation of a Novel Buccal Measles Vaccine
The aim of this study is to develop an orally disintegrating film (ODF) containing a microparticulate measles vaccine formulation for buccal...
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Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies
In today’s global economy and affordable vacation travel, it is increasingly important that visitors to another country and their physician be...
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A Non-Human Primate Model of Aneurismal Subarachnoid Hemorrhage (SAH)
Aneurismal subarachnoid hemorrhage (SAH) is relatively rare form of hemorrhagic stroke, which produces significant social and medical challenges. As...
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Etiology of Crohn’s disease: many roads lead to autophagy
Crohn’s disease is a complex multifactor diseases that occur in individuals with genetic predisposition in whom environmental and microbial triggers...
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Oncolytic viral therapy of malignant glioma
Novel approaches to treatment of malignant glioma, the most frequently occurring primary brain tumor, have included the use of a wide range of...
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Measles Virus-Induced Immunosuppression
Immunosuppression is the major cause of infant death associated with acute measles and therefore of substantial clinical importance. Major hallmarks...
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Divergent Roles for Tumor Necrosis Factor-α in the Brain
Proinflammatory cytokines and chemokines have been implicated in the pathogenesis of several neurological and neurodegenerative disorders. Prominent...
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Pathogenic Viruses: Smart Manipulators of the Interferon System
Vertebrate cells are equipped with specialized receptors that sense the presence of viral nucleic acids and other conserved molecular signatures of...
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Porcine reproductive and respiratory syndrome virus productively infects monocyte-derived dendritic cells and compromises their antigen-presenting ability
Dendritic cells (DC) are potent antigen-presenting cells that play an important role in inducing primary antigen-specific immune responses. However,...