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Malignant Glioma
This chapter provides a comprehensive overview of malignant gliomasMalignant glioma, the most common primary brain tumorPrimary brain tumor in...
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Expression of STAT3 and hypoxia markers in long-term surviving malignant glioma patients
BackgroundGlioblastoma is a malignant and aggressive type of central nevous system malignancy characterized by many distinct biological features...
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Focused ultrasound combined with miR-1208-equipped exosomes inhibits malignant progression of glioma
BackgroundExosomes (Exos) can safely and effectively deliver therapeutic substances to glioma cells; however, their blood–brain barrier (BBB)...
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GAS5 attenuates the malignant progression of glioma stem-like cells by promoting E-cadherin
It has been widely reported that glioma stem-like cells (GSCs) serve a crucial role in the malignant progression of glioma. In particular, recent...
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The promoting effect and mechanism of MAD2L2 on stemness maintenance and malignant progression in glioma
BackgroundGlioblastoma, the most common primary malignant tumor of the brain, is associated with poor prognosis. Glioblastoma cells exhibit high...
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Single-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression
Glioma is the most common primary central nervous system tumor in adults. Aquaporin-4, as a water channel protein encoded by AQP4 in the brain, is...
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Glioma
Most adult neurons have exited the cell cycle. Therefore, almost all primary brain cancers in the adult body are related to glial cells. There exists...
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Benign Glioma
BenignBenign gliomaGliomas broadly refers to a heterogeneousHeterogeneous group of slow-growing glial tumors with low proliferative rates and a more...
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Vimentin promotes glioma progression and maintains glioma cell resistance to oxidative phosphorylation inhibition
PurposeGlioma has been demonstrated as one of the most malignant intracranial tumors and currently there is no effective treatment. Based on our...
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CSF Biopsy in Glioma: A Brief Review
Glioma is the most common intracranial malignant tumor. Over the past several years, liquid biopsy in diagnosis and treatment of solid tumors have...
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ZDHHC15 promotes glioma malignancy and acts as a novel prognostic biomarker for patients with glioma
BackgroundGlioma is the most common and aggressive tumor in the adult brain. Recent studies have indicated that Zinc finger DHHC-type...
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Sevoflurane inhibits the malignant phenotypes of glioma through regulating miR-146b-5p/NFIB axis
PurposeSevoflurane is a common used inhaled anesthetic that was reported to regulate the progression of multiple cancers. Here, we aimed to...
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Circ_0001588 Upregulates ERBB4 to Promote Glioma Malignant Progression Through Sponging miR-1281
Circular RNA (circRNA) plays a crucial part in glioma progression. However, the function of circ_0001588 in glioma development is still unknown. The...
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Glioma hexokinase 3 positively correlates with malignancy and macrophage infiltration
BackgroundGlioma is the main subtype of primary central nervous system (CNS) tumor with high malignancy and poor prognosis under current therapeutic...
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A prognostic neural epigenetic signature in high-grade glioma
Neural–tumor interactions drive glioma growth as evidenced in preclinical models, but clinical validation is limited. We present an epigenetically...
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Radiosynthesis of a novel antisense imaging probe targeting LncRNA HOTAIR in malignant glioma
BackgroundLong non-coding RNA (LncRNA) HOTAIR was amplified and overexpressed in many human carcinomas, which could serve as a useful target for...
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From bench to bedside: the application of cannabidiol in glioma
Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to the intrinsic...
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Genes of the Ubiquitin Proteasome System Qualify as Differential Markers in Malignant Glioma of Astrocytic and Oligodendroglial Origin
We have mined public genomic datasets to identify genes coding for components of the ubiquitin proteasome system (UPS) that may qualify as potential...
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CD93 is Associated with Glioma-related Malignant Processes and Immunosuppressive Cell Infiltration as an Inspiring Biomarker of Survivance
Previous reports have confirmed the significance of CD93 in the progression of multiple tumors; however, there are few studies examining its immune...
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HK3 stimulates immune cell infiltration to promote glioma deterioration
BackgroundGlioma is the most common and lethal type of brain tumor, and it is characterized by unfavorable prognosis and high recurrence rates. The...
