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Impact of age on central lymph nodes involvement in papillary thyroid cancer
BackgroundTotal thyroidectomy is the main line of treatment for papillary thyroid cancer. Central lymph node dissection (CLND) is still debatable. In...
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Sentinel lymph nodes in melanoma: necessary as ever for optimal treatment
Lymphatic metastasis is the dominant route of initial spread for most solid tumors. For many such malignancies, including melanomas, surgical...
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Cell shape sensing licenses dendritic cells for homeostatic migration to lymph nodes
Immune cells experience large cell shape changes during environmental patrolling because of the physical constraints that they encounter while...
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Advantages of contrast-enhanced ultrasound in the localization and diagnostics of sentinel lymph nodes in breast cancer
Sentinel lymph nodes (SLNs) are the first station of lymph nodes that extend from the breast tumor to the axillary lymphatic drainage. The...
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Acute stress transiently activates macrophages and chemokines in cervical lymph nodes
Acute restraint stress (RS) is routinely used to study the effects of psychological and/or physiological stress. We evaluated the impact of RS on...
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The presence of Mott cells in the lymph nodes of rats with experimental autoimmune encephalomyelitis
Mott cells are plasma cells that have multiple spherical Russell bodies packed in their cytoplasm. Russell bodies are dilated endoplasmic reticulum...
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Differentiation of benign and metastatic lymph nodes in soft tissue sarcoma
Lymph node metastasis (LNM) occurs in less than 5% of soft tissue sarcoma (STS) patients and indicates an aggressive course of disease. Suspicious...
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Modified staging system of positive lymph nodes based nomogram in intrahepatic cholangiocarcinoma
BackgroundIntrahepatic cholangiocarcinoma (iCCA) presents the similar trend and prevalence of lymph node metastasis to other biliary tract cancer....
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Clinical features and imaging examination assessment of cervical lymph nodes for thyroid carcinoma
BackgroundsThe purpose of this study is to investigate the relationship between clinical characteristics and cervical lymph node metastasis (LNM) in...
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Identification of Cancer-Associated Fibroblasts in Metastatic Lymph Nodes of Colorectal Carcinoma
Cancer-associated fibroblasts (CAF) are a heterogeneous group of tumor microenvironment cells that are barely studied in metastatic lymph nodes. The...
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Comparison of the distribution of lymph node metastases compared to healthy lymph nodes in breast cancer
BackgroundCurrent literature lacks a comparison of lymph node metastases and non-pathological lymph nodes distribution in breast cancer patients. The...
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Machine learning to predict occult metastatic lymph nodes along the recurrent laryngeal nerves in thoracic esophageal squamous cell carcinoma
PurposeEsophageal squamous cell carcinoma (ESCC) metastasizes in an unpredictable fashion to adjacent lymph nodes, including those along the...
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Refining gastric cancer staging: examining the interplay between number and anatomical location of metastatic lymph nodes - a retrospective multi-institutional study
BackgroundThe current gastric cancer staging system relies on the number of metastatic lymph nodes (MLNs) for nodal stage determination. However,...
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The use of longitudinal CT-based radiomics and clinicopathological features predicts the pathological complete response of metastasized axillary lymph nodes in breast cancer
BackgroundAccurate assessment of axillary status after neoadjuvant therapy for breast cancer patients with axillary lymph node metastasis is...
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Necessity of external iliac lymph nodes and inguinal nodes radiation in rectal cancer with anal canal involvement
Background and purposeWe aimed to explore the necessity of the external iliac lymph nodes (EIN) along with inguinal nodes (IN) region in clinical...
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Risk stratification of oesophageal squamous cell carcinoma using change in total lesion glycolysis and number of PET-positive lymph nodes
BackgroundThe efficacy of neoadjuvant chemotherapy (NACT) correlates with patient survival in oesophageal squamous cell carcinoma (OSCC), but optimal...
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Correlation of Cytokine Content in the Lymph with the Morphological Parameters of the Mesenteric Lymph Nodes in Adjuvant Therapy of Experimental Breast Cancer with the Use of Fragmented Human DNA
We studied the relationship between the level of cytokines in the lymph of the thoracic duct and the morphometric parameters of the mesenteric lymph...
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A Novel Fully Automated MRI-Based Deep-Learning Method for Segmentation of Nasopharyngeal Carcinoma Lymph Nodes
PurposeNasopharyngeal carcinoma (NPC) is epidemic in south China, especially in Guangdong province. Radiotherapy is the main treatment, with the...
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Size and number of lymph nodes were risk factors of recurrence in stage II colorectal cancer
BackgroundSize and number of lymph nodes (LNs) were reported to be associated with the prognosis of stage II colorectal cancer (CRC). The purpose of...